Welcome to the kidney! R Ariel Gomez & team examine the role of renin cells in renal neurovascular morphogenesis & remodeling. The video: mouse kidney cortex with renin cells (magenta), the renal arterial tree (green), nerve fibers (yellow): doi.org/10.1172/jci.... @the-asci.org

Clinical-academic training is under strain. To understand why, we followed-up all UCL MBPhD graduates 131 graduates published >5,800 papers with citations 3x the field norm We identified barriers to training, relevant for all physician-scientists, to inform change www.medrxiv.org/content/10.6...

Integrated MB-PhD training is a long-term investment in the clinician-scientist workforce

Background: Clinician-scientists translate clinical observation into discovery, trials, and policy, yet this workforce is shrinking across health systems worldwide. Integrated MB-PhD training, pausing...

medrxiv.org

Integrated MB-PhD training is a long-term investment in the clinician-scientist workforce https://www.medrxiv.org/content/10.64898/2026.08.26.26361003v1

Angiopoietin-1 RNA therapy slows the progression of WT1 glomerular disease in a preclinical mouse model @ucl.ac.uk www.science.org/doi/10.1126/...

Cambridge → Boston → Cambridge again: I’m thrilled to return to Cambridge(UK) to open my lab at the Gurdon Institute, University of Cambridge!🥳 (mzhulab.com) We study how dev timing shapes and being shaped by plasticity, evolution & ageing. 🚩Hiring at all levels: pls email me if interested!📩

Meng Zhu Lab

We study how development measures time and how timing matters in development, evolution and ageing.

mzhulab.com

Please check out our job post @biologists.bsky.social! We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens! bit.ly/3La9idq

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

Kidney transplant rejection linked to changes in lymphatic vessels Researchers found that when a kidney transplant is rejected, the lymphatic vessels around the transplanted kidney undergo changes, making it easier for the immune system to attack the new organ. www.ucl.ac.uk/news/2025/se...

Kidney transplant rejection linked to changes in lymphatic vessels

A link between kidney transplant rejection and changes in the body’s lymphatic vessels has been discovered in a UCL-led study.

ucl.ac.uk

Take a peek: This issue’s cover features 3D imaging and single-cell genomics by David A. Long @daniyaljafree.bsky.social & team, revealing lymphatic rewiring in kidney tissue with chronic transplant rejection: buff.ly/BZEw4az

Study pinpoints reason why transplanted kidneys can be rejected. Research by Prof David Long, @daniyaljafree.bsky.social (@uclchildhealth.bsky.social) and colleagues @greatormondst.bsky.social, Wellcome Sanger and University of Cambridge. bit.ly/47NIU1V @uclpophealthsci.bsky.social

Study pinpoints reason why transplanted kidneys can be rejected, scientists say

Experts used new imaging techniques to look at the organ’s ‘plumbing system’ to understand what these vessels do during transplantation.

independent.co.uk

An in-depth look at lymphatic reorganization! This issue’s cover features 3D imaging and single-cell genomics by David A. Long, @daniyaljafree.bsky.social & team, revealing lymphatic rewiring in kidney tissue with chronic transplant rejection: buff.ly/BZEw4az

🚨 New paper in @jclinical-invest.bsky.social! Kidney lymphatics are a promising target in transplant rejection 🗺️ In rejection, lymphatics expand and adversely remodel ⚡️ Although they have an anti-inflammatory profile, they are attacked by the immune system www.jci.org/articles/vie... 1/4

First of its kind study for children with arthritis reveals possible new disease targets. Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently. Read: www.ucl.ac.uk/news/2025/ju...

First of its kind study for children with arthritis reveals possible new disease targets

Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently.

ucl.ac.uk

I'll soon be advertising for a 3 year postdoc to join our lab at @edinuni-irr.bsky.social exploring #macrophages in salivary gland #development. Candidates should have a strong background in immunology/macrophage biology and/or developmental biology & key skills as below. Informal enquiries welcome!

Excited to share our new collaborative preprint between @uclnews.bsky.social and @sickkidsto.bsky.social 🥳 We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney www.biorxiv.org/content/10.1... (1/4)

Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphatics

The lymphatic vasculature is essential for fluid homeostasis, immune regulation and possesses diverse organ-specific functions. During development, lymphatic endothelial cells (LEC) arise from multipl...

biorxiv.org

🧪 Job alert 🔊 we are hiring a Research Assistant - join the Simões Group at DPAG-IDRM @ox.ac.uk supporting #cardiovascular development and regeneration research, working with #zebrafish and #human stem cell systems: my.corehr.com/pls/uoxrecru... @oxforddpag.bsky.social @idrm.ox.ac.uk (1/4)

PhD position available in our team @dublincityuni.bsky.social from September. Please share/ contact me for informal enquiries.

For #FluorescenceFriday I'm sharing the fantastic work of postdoc Sarah McLarnon! A follow up to our '23 Development paper where we asked: Does precise vascular patterning matter for function and what happens after ischemic injury? The results were surprising! journals.physiology.org/doi/full/10....

Thrilled to share our new work in Nature Communications! We discovered how methionine → SAM → METTL3 → RNA methylation axis guides kidney development, especially nephron progenitor differentiation. #Nephrology #Epitranscriptomics Here’s a quick breakdown www.nature.com/articles/s41...

An RNA transmethylation pathway governs kidney nephrogenic potential - Nature Communications

The mechanisms governing kidney nephrogenic capacity are incompletely understood. Here, the authors reveal that METTL3-dependent RNA transmethylation is both necessary and sufficient to promote nephro...

nature.com

Delighted to be a Accelerator Award recipient @wellcometrust.bsky.social 🥳 I’ll work at @uclnews.bsky.social + @sangerinstitute.bsky.social, diving into how lymphatic vessels regulate immunity, whilst building clinical experience at @greatormondst.bsky.social wellcome.org/grant-fundin... (1/4)

Thrilled to share a new paper from my PhD in David Long’s lab at UCL, published in the Disease Models & Mechanisms journal! doi.org/10.1242/dmm.... We studied kidney microvasculature in polycystic kidney disease (PKD), the most common genetic cause of kidney failure (1/5)