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Daniel McManus, PhD

@danmcmanus123.bsky.social

Immunologist, Postdoctoral Fellow, Satpathy Lab, Stanford

7 Posts82 Follower112 Folgt
Open Box Science @openboxscience.bsky.social · 2mo ago

OBS Immunology Seminar| Young Investigator Highlight 'Decoding T Cell Exhaustion: An Epigenetic Roadmap to Enhance Cancer Immunotherapy' Hazem E. Ghoneim, PhD Assoc. Prof. The Ohio State University Thurs, June 11th, 2026 11am ET | 10am CT | 8am PT Zoom below

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Open Box Science @openboxscience.bsky.social · 3mo ago

OBS Immunology Seminar| Young Investigator Highlight 'Comprehensive genetic manipulation of human immune cells' Theodore L. Roth, MD PhD Asst. Prof. of Pathology Stanford 🎙️@danmcmanus123.bsky.social Thurs, May 14th, 2026 1pm ET | 12pm CT | 10am PT Zoom below

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Open Box Science @openboxscience.bsky.social · 8mo ago

Don't miss the Nature Reviews Immunology webinar on new T cell nomenclature guidelines! Monday, Dec 8, 2025 09:00 PST | 12:00 EST | 17:00 GMT | 18:00 CET Register here: t.co/pe6GYY4AsS

https://z.umn.edu/Tcellnomenclature

t.co

Nature Reviews Immunology@natrevimmunol.nature.com · 8mo ago

See the new consensus statement on 'Guidelines for T cell nomenclature': www.nature.com/articles/s41... Register to join our webcast on Monday 8th December www.workcast.com/register?cpa...

Daniel McManus, PhD@danmcmanus123.bsky.social · 11mo ago

Great new work from Will Hudson’s lab at @bcmhouston.bsky.social on the role of CD7 during CD8 T cell exhaustion! tinyurl.com/3c5mdyzr hudsonlaboratory.com @cp-cellreports.bsky.social

CD7 regulates the persistence of terminally exhausted CD8+ T cells during chronic infection

Hyslop et al. identify CD7 as a tissue-specific receptor essential for maintaining terminally exhausted CD8+ T cells during chronic infection. CD7 is highly expressed on a CD101+Tim3low liver-resident...

tinyurl.com

Daniel L. Barber, PhD@danbarberphd.bsky.social · 11mo ago

We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!

Yannick Alexandre@yannick-alexandre.bsky.social · last yr.

I’m pleased to share my latest work, published in Science Advances. In this study, we investigated how fibroblastic reticular cells (FRCs) that populate the white pulp of the spleen regulate immune responses to viral infections. #immunology #immunosky www.science.org/doi/10.1126/...

Splenic fibroblastic reticular cells orchestrate dendritic cell maturation and facilitate CD8+ T cell priming and protective memory

Fibroblastic reticular cells of the spleen coordinate inflammation for optimal antiviral T cell responses and protective memory.

science.org

Prof. Shane Crotty@profshanecrotty.bsky.social · last yr.

One of our obsessions in the Crotty lab is to better understand B-cell immunology in the context of vaccines. Rare B cells can have antibody specificities particularly important for protection against some diseases. In our most recent paper… @cp-immunity.bsky.social www.cell.com/immunity/ful...

Diverse priming outcomes under conditions of very rare precursor B cells

B cells that give rise to neutralizing antibody responses can be extremely rare in the naive B cell repertoire. Madden et al. show that delivery strategy and adjuvant selection affect the recruitment ...

cell.com

Joanna Groom@groomlab.bsky.social · last yr.

Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” @wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social Thread below.

Journal of Experimental Medicine@jem.org · last yr.

@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...

Nik Joshi@joshilabyale.bsky.social · last yr.

My wife and I were postbac IRTAs 25 years ago. Neither would have pursued a career in research if not for this program We have PhD students in Yale Immunobiology now who also came from this NIH program including (one amazing student in my lab) This is a valuable program and has been for decades.

Kathleen Bachynski@bachynski.bsky.social · last yr.

One of the many, many “pauses” and cancellations devastating our next generation of researchers. “The NIH Intramural Program has paused the recruitment of IRTAs, CRTAs, and Visiting Fellows in all training programs pending guidance from Health and Human Services. Check back daily for updates.”