Big news in the Long COVID world: "In pre-specified subgroup analyses...patients with greater baseline burden on one or more symptoms (approximately 78% of trial participants) demonstrated statistically significant improvements on multiple clinically coherent endpoints."

BioVie Announces Topline Results from Phase 2 ADDRESS‑LC Trial Evaluating Bezisterim for the Treatment of Neurological Symptoms Associated with Long COVID

Statistically significant benefits observed in bezisterim-treated Long COVID patients in pre-specified subgroups with high baseline fatigue, cognitive impairment, and/or post‑exertional malaise Bezist...

investors.bioviepharma.com

Ezra S@ezra.zone · 15h ago

Looking forward to participating in this event! investors.bioviepharma.com/news/news-de...

Master post of each talk re: the Stanford #MECFS Community Symposium: 🧪 Talk 1: bsky.app/profile/exce...

It's ME(Jaime)@exceedhergrasp1.bsky.social · 4d ago

Todd Davenport from Uni of the Pacific is up first!

I'm featured alongside colleagues from UCSF in this overview of Long COVID research and reasons for hope for the future: www.smithsonianmag.com/innovation/m... There's an audio version on apple news (behind a paywall unfortunately): apple.news/AxJhSAYZ3Sze...

Three cheers for the incredible @julialmv.bsky.social 👏🏻🥳 And to the wonderful UCSF team featured as well! @michaelpelusomd.bsky.social Gratitude to these Long Covid researchers & to @smithsonianmag.bsky.social for covering them 🙏

Eric Topol@erictopol.bsky.social · 2w ago

On #LongCovid and profiling my colleague @julialmv.bsky.social @smithsonianmag.bsky.social www.smithsonianmag.com/innovation/m...

This Smithsonian magazine piece featuring my friend @julialmv.bsky.social is one of the best popular accounts I’ve read of Long Covid and the current state of science. Highly recommend.

For Many Americans, Covid Is Still a Chronic, Disabling Disease. These Scientists Are Working Tirelessly to Bring Them Relief

Long Covid saps the strength and vitality of patients, who have little recourse to fight it. A team of specialists—including an afflicted researcher working mostly from her bed—is looking for answers

smithsonianmag.com

On #LongCovid and profiling my colleague @julialmv.bsky.social @smithsonianmag.bsky.social www.smithsonianmag.com/innovation/m...

For Many Americans, Covid Is Still a Chronic, Disabling Disease. These Scientists Are Working Tirelessly to Bring Them Relief

Long Covid saps the strength and vitality of patients, who have little recourse to fight it. A team of specialists—including an afflicted researcher working mostly from her bed—is looking for answers

smithsonianmag.com

Self-directed antibodies are found in people with #LongCovid. A key source of these was identified, and these autoantibodies and cell origin are also seen in lupus. @cp-immunity.bsky.social www.cell.com/immunity/ful...

To help us grow our newsletter, we’re trying out a referral program. We think this will make it easier for readers like you to share the newsletter with other community members. But we need your help to test it out!

PLRC member @julialmv.bsky.social published a piece in @thelancetinfdis.bsky.social highlighting how quickly her team completed recruitment for the LoCITT-T clinical trial. They recruited 1,000 people in less than two months — a feat many other trialists doubted was possible. 1/

“A direct-to-participant, siteless infrastructure can … reach severely affected participants who are routinely excluded by site-based designs.” #LongCovid

Julia MV@julialmv.bsky.social · 3w ago

New preprint from LoCITT-T describing our protocol and lessons learned. www.medrxiv.org/content/10.6... Thank you to all LoCITT-T participants for their efforts and engagement, and to all caregivers who supported their participation. 1/8

What's so cool about this to me (disclaimer: I have a small, compensated role on this project) is that it shows how trials don't just need to test innovative treatments – they need to have innovative operations to fully represent the spectrum of people affected.

Julia MV@julialmv.bsky.social · 3w ago

New preprint from LoCITT-T describing our protocol and lessons learned. www.medrxiv.org/content/10.6... Thank you to all LoCITT-T participants for their efforts and engagement, and to all caregivers who supported their participation. 1/8

New preprint from LoCITT-T describing our protocol and lessons learned. www.medrxiv.org/content/10.6... Thank you to all LoCITT-T participants for their efforts and engagement, and to all caregivers who supported their participation. 1/8

Insights from a double-blind, randomized, direct-to-participant intervention trial for Long COVID

Background. Long COVID affects an estimated 400 million people worldwide, and is associated with low quality of life. Nearly all completed Long COVID clinical trials reported no benefit, and most requ...

medrxiv.org

Wow. Just skimming this paper & it’s extremely validating. All the ways we’re pressured & shamed into hiding our reality & apt emotions due to affective injustice. I feel it in almost every interaction I have with anyone who doesn’t have ME. It’s that omnipresent. link.springer.com/article/10.1...

ME/CFS and the emotional toll of persistent disbelief: from epistemic to affective injustice - Medicine, Health Care and Philosophy

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating chronic illness whose sufferers are frequently met with disbelief, stigmatization, and psychologization in both clinical a...

link.springer.com

Good review on Postural Orthostatic Tachycardia Syndrome (POTS) today @jama.com jamanetwork.com/journals/jam...

This description of living with severe ME is so spot on: "All you can do is hope to outlast the storm without going under."

Miles W. Griffis@mileswgriffis.bsky.social · 4w ago

“ME is like being in a raging storm while caught in the open ocean. You can’t think, you can’t breathe, and you are constantly thrown about by circumstances out of your control.” thesicktimes.org/2026/08/21/h...

Just like all previous summers since the pandemic began, COVID-19 cases are ticking up again, even while other health threats make more headlines. n.pr/45oln5k

Is there a summer COVID-19 surge this year? Yep, it's ramping up again

Just like all previous summers since the pandemic began, COVID-19 cases are ticking up again, even while other health threats make more headlines.

n.pr

On the consequences of de-funding ongoing clinical trials (gift link): www.nytimes.com/2026/08/10/o... "Stopping a study midway doesn’t make the question disappear. It means we may never get the answer, even after taxpayers have paid millions toward finding it."

Opinion | Medical Breakthroughs Are a Thrill. Then Comes the Hard Part. (Gift Article)

The Trump administration has dismantled the agency that ensures that research makes its way into medical practice.

nytimes.com

Severe Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...

Virus reactivation in acute and long COVID-19 - Nature

Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...

nature.com

"The idea that exercise is the best medicine for all people with POTS still lingers. As Davenport noted, “We need to interrogate who has the fear here. We can’t be afraid of not exercising.” @sweetsciencewriter.bsky.social's write up on the DI conference for TST 🫀 thesicktimes.org/2026/07/28/d...

Dysautonomia conference centers biomarkers and post-exertional malaise - The Sick Times

The 14th annual Dysautonomia International conference outside Houston included presentations on the role of autoimmunity in dysautonomia and a biobank initiative for POTS research.

thesicktimes.org

I submitted an ER story - and was glad to know that Jamie and the @meactnet.bsky.social team will put the experience to good use. I encourage others with ME and LC to share ER their stories here: surveys.mayoclinic.org/jfe/form/SV_...

It's ME(Jaime)@exceedhergrasp1.bsky.social · 2mo ago

The survey has 100+ unique emergency room narrative responses already! But we're aiming for 150 before we close. If you have a diagnosis of #MECFS or #LongCOVID and have been to the emergency room in the past 10 yrs for your symptoms, I hope you'll take the survey. And if you don't, please share!

Hats off to @julialmv.bsky.social and the entire LoCITT-T team for making the impossible possible. www.thelancet.com/journals/lan...

Rapid recruitment for a remote long COVID clinical trial

There have been few long COVID clinical trials relative to the burden of disease,1 and even fewer have been accessible to people with more severe illness.2 As a person who has had moderate-to-severe l...

thelancet.com

The story of rapid recruitment for our tirzepatide trial is now published in Lancet ID: www.thelancet.com/journals/lan... "Although the large-scale interest in LoCITT-T met my expectations, I had not anticipated the influx of kind words about the trial from the [Long COVID] patient community." ❤️

Rapid recruitment for a remote long COVID clinical trial

There have been few long COVID clinical trials relative to the burden of disease,1 and even fewer have been accessible to people with more severe illness.2 As a person who has had moderate-to-severe l...

thelancet.com

Hey folks, I'm a researcher with ME/CFS & I am sharing an opportunity to participate in a research study. The study is open to people with ME/CFS, medical or healthcare providers, and researchers who have had at least one patient/person with ME/CFS. Visit restandmecfs.com for more!

Going on a trip? Don’t let COVID-19 crash your summer plans. Wearing an N95 mask protects you from respiratory viruses like COVID-19. Consider wearing a mask in indoor and crowded places like airports and planes. Learn more: go.cdph.ca.gov/respiratory-viruses

Looking to speak with any Black folks in New Mexico, Arizona, Missouri, Maryland, Arkansas, Kansas, Oklahoma, Tennessee, Washington, Florida, Georgia, Alabama, or Colorado (whew) who have had their Medicaid or SNAP benefits abruptly canceled! (I’m writing about how AI systems are denying benefits)

"Like Mari, many disabled people rely on others to meet their most basic survival needs. When adequate support from governments and medical systems is not available, this level of dependency places disabled people at high risk of neglect, exploitation, and abuse." 1/3

The Sick Times@thesicktimes.org · 2mo ago

Many disabled people rely on others to meet their most basic survival needs. When adequate support from governments and medical systems is not available, this level of dependency places disabled people at high risk of neglect, exploitation, and abuse. thesicktimes.org/2026/07/20/a...

Are you someone with myalgic encephalomyelitis/chronic fatigue syndrome #MECFS or #LongCOVID who’s been to the emergency room at least once over the past 10 years for your symptoms? Clinical care needs your voice! Take the Emergency Department research survey: surveys.mayoclinic.org/jfe/form/SV_...

This is a delay from estimates shared earlier in the year -- at the January RECOVER-TLC webinar, speakers said that the LDN and GLP-1 trials would potentially start this summer. thesicktimes.org/2026/01/23/n...

New RECOVER-TLC trials won’t enroll until summer. Nearly two years after the program’s launch. - The Sick Times

The RECOVER-Treating Long COVID initiative is set to begin enrolling participants in new clinical trials this summer, which will mark nearly two years after the National of Institutes of Health (NIH) ...

thesicktimes.org

📣 I’m writing a story with The Sick Times focusing on why there are no clinical guidelines for treating children with #LongCOVID and how this affects families. If you're a family affected by Long COVID, feel free to get in touch - felicity.nelson@frogsandstars.com.

Today’s the final day of our summer sustainability fundraiser and we could really use your help! Sign up to become a monthly donor at any amount, and keep our Long COVID journalism going.

The Sick Times@thesicktimes.org · 2mo ago

🚨🙀‼️: Our summer fundraiser ends tomorrow at midnight and we need your help to cross the finish line! We’re aiming to gain 88 more Supporters. Monthly donors, even at $1 a month, help us in our mission in becoming a more sustainable newsroom.