It's incredible how expansion microscopy has advanced in the past few years. Check out @lydia-kisley.bsky.social ’s lab latest preprint showing their new device for this field! @prelights.bsky.social prelights.biologists.com/highlights/t...

The Tensile Expansion Microscopy (TExM) cell stretcher: an iris expansion device integrated with automated real-time autofocus and tracking to super-resolve cells - preLights

A new stretch-o-matic? Meet the tensile expansion microscopy device !

prelights.biologists.com

Issue 18 is complete Explore our Toc: journals.biologists.com/jcs/issue/13... Our cover image is an osteosarcoma cell visualised by structured illumination microscopy showing actin (magenta), paxillin (green) & myosin-X (cyan). See research by Popović et al. journals.biologists.com/jcs/article/...

Did you ever wonder how the leopard got its spots? Or how the zebra got its stripes? Wonder no more! In this #Short, @benswedlund.bsky.social talks about his #preprint describing reaction-diffusion architecture for engineering self-organised patterns in mammalian cells. 🎙️⬇️ youtu.be/_HMbr4KE1PI?...

spotLights Ep 23: Benjamin on programming self-organising cell patterns #syntheticbiology #biology

YouTube video by The Company of Biologists

youtu.be

Had a wonderful experience editing this one, thanks to the authors for sharing their comments and drafting answers together ! @lindithium.bsky.social @huanting-ong.bsky.social @jennyoung.bsky.social ng.bsky.social

preLights@prelights.bsky.social · last mo.

Two #preprints detail new & complementary ways to match mechanical readouts from tissues to OMICs. #preLight by @fadelvalle.bsky.social - includes a discussion with the author teams @lindithium.bsky.social @huanting-ong.bsky.social @jennyoung.bsky.social ⬇️ prelights.biologists.com/highlights/m...

Happy to see my latest preLight featured in this great issue 😬

Development@dev-journal.bsky.social · 2mo ago

Also in #DevSIextracellular: ▪️Editorial ▪️2 interviews with our Guest Editors ▪️Spotlight on apical extracellular matrix development ▪️Primer on mechanics ▪️4 Reviews ▪️22 Research Articles and Reports ▪️2 Techniques and Resources ▪️1 Preprint highlight Full table of contents: tinyurl.com/bdr4ymvr

The clock under pressure 🕰️ Chun-Yen Sung & colleagues demonstrate how presomitic mesoderm cells sense physical rigidity to control developmental timing. #preprint #preLight by @fadelvalle.bsky.social ⬇️ prelights.biologists.com/highlights/m...

Matrix Rigidity Governs Switch-Like Oscillatory State Transitions of the Segmentation Clock in Isolated Presomitic Mesoderm Cells - preLights

The clock under pressure: How presomitic mesoderm cells sense physical rigidity to control developmental timing

prelights.biologists.com

Hämälistö, @fadelvalle.bsky.social, Yuseff, and @mattilalab.bsky.social review how #BCells have adopted specialized ways to use endolysosomal vesicles to promote adaptive immune responses. rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...

From cells to amino acids: 1000ExM pushes expansion microscopy even further 🔬 #microscopy @fadelvalle.bsky.social covers an impactful #preprint from the labs of @bergerlab.bsky.social, @alishaib.bsky.social, Silvio Rizzoli & @eboyden3.bsky.social #preLight⬇️ prelights.biologists.com/highlights/t...

Thousandfold Expansion Microscopy - preLights

From cells to amino acids: 1000ExM pushes expansion microscopy beyond 1000×, potentially resolving individual protein residues on standard microscopes. Bigger volume expansion opens a new frontier for...

prelights.biologists.com

🚨 First preprint from the lab! @pdaphd.bsky.social summarises the findings in this thread. Congrats to @rhyslivingstone.bsky.social and @pdaphd.bsky.social for all the hard work I’ve witnessed 🎉🥳

Paul Donlin-Asp@pdaphd.bsky.social · 7mo ago

Extremely excited to share the first preprint from the lab, led by postdoc @rhyslivingstone.bsky.social www.biorxiv.org/content/10.6... What has he found? 1/7

Thanks to @jcb.org for featuring my PhD work ! So many interesting articles in this collection 🔥

Journal of Cell Biology@jcb.org · 7mo ago

B cell mechanotransduction via ATAT1 coordinates #actin & lysosomal dynamics at the immune synapse. From Pablo Aceitón, Isidora Riobó, @fadelvalle.bsky.social, María Isabel Yuseff et al. rupress.org/jcb/article/... 📕 From JCB Immune Cell Biology collection 👉 rupress.org/jcb/collecti... #AAI2026

The 2025 ASAPbio Fellows examined how large language models (LLMs) handle, interpret, and communicate information from preprints compared to peer-reviewed journal articles. The new blog post discussed their findings👇️ buff.ly/SSglQZG

Interim Findings From An Investigation Into LLM Responses About Preprints: A 2025 ASAPbio Fellows Project – ASAPbio

Contributors: Felipe Del Valle Batalla, Barakat Bakhit, Akanksha Gupta, Kendra Parson, Emiliya Taskova

asapbio.org

Happy FluoFriday Y'all !

Best comment and summary of the whole situation

Alex Merz@merz.bsky.social · 10mo ago

I prefer scientists like our colleague Doug Zonkger, who are willing to put in the work.

"AI tools are democratizing Coding" My dude, R and Python are free and open-source

It's been a while , but back in the bluest of skies :) ! here's some late #microscopymonday pic

Happy fluorescence Friday ! First one of the year :)

Mid-Week Microscopy !

In a short time, we’ll have fake AI scientists fabricating fake AI results reviewed by fake AI reviewers. This data will then be text-mined by AI and ultimately delivered to mindless AI consumers.

Pedro Beltrao@pedrobeltrao.bsky.social · 12mo ago

Finally the scary example. The image of a western blot with a time course experiment, staining a protein of interest, showing the increase of protein over time and a second staining with a control antibody that does not change over time

I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange). Also the membrane dynamics are lovely. It's been a while, but here we are for a late #fluorescencefriday with some #microscopy #scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬

www.nmccarty.com/p/30-essays?... Great picks ! (also an amazing substack)

30 Great Essays About Biology

If you read one a day, you may just fall in love.

nmccarty.com

#FluorescenceFriday once again <3

Not all colormaps are created equal. Notice the nonlinear brightness scaling in two very popular ImageJ LUTs! (Glow & GFB)

This is what I actually signed up for ❤️ gloomy scientific vibes 🏴󠁧󠁢󠁳󠁣󠁴󠁿

😍

🥳

Seema Grewal@seemagrewal.bsky.social · last yr.

Happy birthday @biologists.bsky.social! 🥳 Here’s to another century of supporting biologists and inspiring biology!

Falkirk for the day ❤️

As per usual: NEVER. Enough. L U T S

Kevin Terretaz@kwolbachia.bsky.social · last yr.

I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager! I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...

Happy October 1st! A good time to share another #CellBio #preprint reading list put together by a team of preLighters: @sristi.bsky.social, Matthew Davies, @vibhasingh.bsky.social, @fadelvalle.bsky.social & Barbora Knotkova. Check out their picks ⬇️👀 prelights.biologists.com/prelists/sep...

September in preprints – Cell biology edition - preLights

prelights.biologists.com

Could run forever with these views 🏴󠁧󠁢󠁳󠁣󠁴󠁿

Fiji is just: