Nik Georgopoulos
@drnikg.bsky.social
Associate Professor in Cell Biology & Transforming Lives Fellow at Sheffield Hallam University. My group is interested in Epithelial Cell Biology, Cell Death, Cancer Biology and Immunology. "There is only one good, knowledge, and one evil, ignorance".
Hinley et al.: Connexin 32 sustains urothelial quiescence and limits TGFβ-driven remodelling, revealing a luminal MIBC split. @biologyatyork.bsky.social @ybri-uoy.bsky.social @jennybaker.bsky.social @drsimonbaker.bsky.social @asmasonomics.bsky.social www.life-science-alliance.org/content/9/5/...
An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/63321Aqwbc Douglas Hanahan @cp-cell.bsky.social
What happens between Manuscript submission date & Manuscript acceptance date
Fully funded PhD opportunity! And there is still time to apply. Email me if you're interested.
Mari Herigstad@herigstad.bsky.social · 10mo agoCome do a PhD with us. We have an exciting multidisciplinary project available, joint between Sheffield Hallam and University of Sheffield, to determine the metabolic impact of air pollutant carbon monoxide. Ad here: www.findaphd.com/phds/project... Please share!
New paper out! This is the basis of our nanoformulation product for delivery with scalp cooling. A step closer to dramatic improvement in efficacy and prevention of hair loss during chemotherapy. @scalpcooling.bsky.social @hallam-biosci-chem.bsky.social www.sciencedirect.com/science/arti...
Formulation and characterisation of resveratrol-loaded nanostructured lipid carriers for use in combination with scalp cooling therapy to mitigate chemotherapy-induced follicular cytotoxicity and hair...
Hair loss represents a highly traumatic side-effect of chemotherapy treatment, it significantly affects psychological well-being, self-esteem and qual…
sciencedirect.com
If Labour are willing to bin their manifesto pledges on tax rises, why not on Brexit? That would win them far, far more votes than raising taxes ever will. Indeed, tax rises are likely to crater their weak support even further. What's so magical about Brexit that it must remain untouchable?
To be part of the largest UK trade delegation ever sent to India was an incredible honour. This is devolution in action. Mayors working with the government to secure the jobs and investment that will put more money in people’s pockets back home.
⚠️ Half of commercial antibodies miss their target! So how do you pick the right one for your experiment? Here’s the solution 👉 Antibody characterization data (all tested in KO cells) are now available at: 🔗 onlygoodantibodies.co.uk Tested by @ycharos.bsky.social & @oga-community.bsky.social
OGA - Only Good Antibodies Community
onlygoodantibodies.co.uk
Cheap airlines means "do not expect decent service" @easyjethelpline.bsky.social @easyjettime.bsky.social. Flight EZY2060 on 03/08/2025 from ATH to MAN: I respect the reasons for the emergency stop in France but 3 flights to MAN was a joke!
Wow an amazing paper by @natureportfolio.nature.com and after so many years it is brilliant to reach a better understanding of why the 'natural' CD40 ligand signal is better and more effective! www.nature.com/articles/s41...
Nanomechanical binding mechanism of ligands drives agonistic activity - Nature Communications
Monoclonal antibodies and ligands targeting CD40 exhibit diverse agonistic and antitumor activities that are influenced by their design. Here, the authors identify mechanistic differences between clin...
nature.com
Cooling caps protect hair during chemo – but only at the right temperature. Antioxidants may help when cooling falls short.
Cooling and antioxidants could help prevent hair loss during chemotherapy – new research
Cooling caps protect hair during chemo – but only at the right temperature. Antioxidants may help when cooling falls short.
tcnv.link
Dr Nik Georgopoulos’s (@drnikg.bsky.social) newly published research has shown for the first time that scalp cooling to an exact temperature combined with topical antioxidants can help to prevent chemotherapy-induced hair loss. Read the full piece below👇
The Conversation UK@uk.theconversation.com · last yr.Cooling caps protect hair during chemo – but only at the right temperature. Antioxidants may help when cooling falls short.
Our milestone publication on scalp cooling research is finally out. Thank you to our amazing industry partner @scalpcooling.bsky.social for funding this research. @hallam-biosci-chem.bsky.social www.frontiersin.org/journals/pha...
Frontiers | Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte cytotoxicity
BackgroundChemotherapy-induced alopecia (CIA) is a distressing side-effect of cancer treatment. Scalp cooling remains the only available method to mitigate C...
frontiersin.org
A brilliant and informative meeting! Congratulations to everyone involved in organising.
Insigneo Institute for Healthcare Technology@insigneoinstitute.bsky.social · last yr.We've had a fantastic day at our Yorkshire MedTech EPSRC #PBIAA Industry Day. We were thrilled to welcome Abtisam Mohammed, MP for Central Sheffield, who joined us for our session on innovation assets in #SouthYorkshire.
Scientists discover that ‘toxic’ Alzheimer’s protein is essential for baby brain development.
Babies have more of this Alzheimer’s-linked protein than dementia patients – study raises hope for future treatments
Scientists discover that ‘toxic’ Alzheimer’s protein is essential for baby brain development.
tcnv.link
This is how you 'encourage' your colleagues to attend a meeting! Chocolate and other snacks! Thank you @herigstad.bsky.social 😊
Michelle and I are thinking of the entire Biden family. Nobody has done more to find breakthrough treatments for cancer in all its forms than Joe, and I am certain he will fight this challenge with his trademark resolve and grace. We pray for a fast and full recovery.
As if the 'Trump administration' has not behaved with complete disregard to humanity already, let's create a reality TV show to insult more human beings. How more abhorrent can you really be...? news.sky.com/story/tv-sho...
Trump officials considerTV show where immigrants compete for US citizenship
The proposed TV show would see immigrants compete in tasks across different states and include trivia and "civic" challenges, according to the producer who pitched it.
news.sky.com
And we did it! Award winners for "Partnership with Academia" and wonderful recognition of such a brilliant collaboration! Well done to both the @hallam-biosci-chem.bsky.social and @scalpcooling.bsky.social teams!
Nik Georgopoulos@drnikg.bsky.social · last yr.We are delighted to have been shortlisted with @scalpcooling.bsky.social for a "Partnership with Academia" award. Wish us luck! medilink.co.uk/the-medilink...
We are delighted to have been shortlisted with @scalpcooling.bsky.social for a "Partnership with Academia" award. Wish us luck! medilink.co.uk/the-medilink...
The Medilink Healthcare Business Awards 2025 - Medilink
The Medilink Healthcare Business Awards has seen some of the industry’s highly commendable innovations receive the recognition they deserve.
medilink.co.uk
...and here we are! 🎉 ECDO has officially joined the Bsky community! Here, we will share the latest news, events, and publications from the ECDO network. 🧬✨ Stay tuned !!!! #ECDO #CellDeathResearch #BLSK #ScientificCollaboration #CellBiology #TranslationalResearch #NewBeginnings
a colorful painting of a cell with a blue nucleus
ALT: a colorful painting of a cell with a blue nucleus
media.tenor.com
Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website: journals.biologists.com/jcs/pages/re...
They screened B cell responses (antibody ) and found a really good contender in NA representing a promising target for broader protection ie potential for a universal vax = fewer vaccines needed maybe in the future 🤞
Identification of a seasonal influenza vaccine–induced broadly protective neuraminidase antibody | Journal of Experimental Medicine | Rockefeller University Press
Madsen et al. identify a neuraminidase-targeting human monoclonal antibody (mAb-297) induced by seasonal influenza vaccination that broadly protects agains
rupress.org
I've already 34 requests for peer review this year, and it is exhausting. I've done a third of them, but the current system is simply not sustainable. It's insane to keep asking people to work for free while multibillion pound corporations pocket the rewards free labour
Matthew Freeman@mjafreeman.bsky.social · last yr.Really interesting experiment by @danielgorelick.bsky.social @biologyopen.bsky.social @biologists.bsky.social Paying peer reviewers to get a super-fast turnaround...
I am grateful to @cancerresearchuk.org for choosing to support our work aiming to understand the links between distorted embryonic development and neuroblastoma initiation using our human pluripotent stem cell differentiation model: www.sheffield.ac.uk/biosciences/...
Understanding the genetic roots of aggressive childhood cancer: Research aims to improve Neuroblastoma treatment
Scientists have secured £1.5 million from Cancer Research UK (CRUK) to investigate the genetic secrets behind neuroblastoma - aiming to improve treatments for this aggressive childhood cancer.
sheffield.ac.uk
This is awful. I know some brilliant hardworking people whose grants were cancelled. The loss of their research puts U.S. lives at risk, hurts our economy, + gives EU & Chinese science & biotech a BIG a leg up on us. We in USA will need to buy foreign drugs & vaccines. www.nature.com/articles/d41...
Exclusive: NIH to cut grants for COVID research, documents reveal
Studies on climate change and South Africa are also on the latest list of grants to be terminated, according to updated documents obtained by Nature.
nature.com
