🥲

C&EN (Chemical & Engineering News)@cenmag.bsky.social · 13h ago

On Tuesday, the American Chemical Society @acs.org displayed a new brand—one that reflects the organization’s evolution, growing global impact, and vision for a world built on science. #chemsky 🧪

By sequencing the genome and through comparative genomics, we found that it doesn't have significant gene family expansions in developmental / information processing genes (e.g. Transcription Factors, signalling pathways). However its large genome (>3Gb) is ~75% transposons. 3/

Man, this stuff is amazing! Check out DABEST2.0 for multi-group comparisons. I was just struggling with how to best account for the block-type set up of my microplate growth experiments and here it is! Sorry, for the censored data. #microsky 🧪

Sangyu Xu@xusangyu.com · 5d ago

DABEST2.0 paper is live! #statistics #reproduciblescience #estimation www.nature.com/articles/s41...

DABEST2.0 paper is live! #statistics #reproduciblescience #estimation www.nature.com/articles/s41...

Getting over ANOVA: estimation graphics for multi-group comparisons - Nature Methods

Nature Methods - Getting over ANOVA: estimation graphics for multi-group comparisons

nature.com

🚨 Faculty Cluster Hire in Crop Design/Synthetic Biology at @universityofga.bsky.social! 🌱 We're hiring 3 open-rank faculty for the Institute of Crop Design. Work in AI, synthetic biology, genome engineering, quantitative genetics, or crop design? Come join us! 🔗 tinylink.net/l48Ms

If you are in any way interested in metabolic engineering, synthetic biology, chemical catalysis or biomanufacturing go and follow: @carboncare-project.eu 🧪

CarboNcare@carboncare-project.eu · last wk.

Hello! We are a new @scienceinnovation.ec.europa.eu project building bacteria that only grow by making methanol-based chemicals instead of releasing CO2. 🌬️🦠 📈 Follow our journey and learn more at carboncare-project.eu Eight partners, six countries, one goal: Fermentation 2.0. #microsky 🧪

Hello! We are a new @scienceinnovation.ec.europa.eu project building bacteria that only grow by making methanol-based chemicals instead of releasing CO2. 🌬️🦠 📈 Follow our journey and learn more at carboncare-project.eu Eight partners, six countries, one goal: Fermentation 2.0. #microsky 🧪

The American mind can’t comprehend

The winning design. 🇪🇺💶

New Preprint 🥳 Here we wondered how phages that have been extensively studied in laboratory E. coli strains actually behave when they encounter a real pathogen such as O157:H7 strain...one with a far more complex cell surface & one of the most consequential foodborne pathogens in the United States.

Animated E. coli Bacteria Drawing

Alt: Animated E. coli Bacteria Drawing

static.klipy.com

The euro banknotes seem to get a new look, and the @ecb.europa.eu has hosted a survey, asking which desing is the preferred one. I really like the stork on the 50€ banknote. surveys.ecb.europa.eu/10b/banknote...

Please share! 🌱🤖 Permanent W2 Professorship in crop & plant sciences @ PhenoRob, University of Bonn. Especially encouraged: crop genome engineering, sustainable pest control, or sustainable disease control. Expertise in one area is enough. Apply by Sept. 30, 2026. www.uni-bonn.de/en/universit...

honestly this is not an unpopular opinion. Many scientists are sympathetic to the position that scientific peers are too conservative or too critical or too dogmatic or just don't get it. But, the alternative is much worse. We should aim to make the scientific process more democratic. Not less.

(1/16) Nearly two-thirds of ocean carbon fixation flows through a diverse organelle: the pyrenoid. Our new paper maps its 3D architecture in the alga Chlorella and identifies new proteins — expanding the toolkit to engineer this CO2-concentrating machine into crops🧵 #Pyrenoid #CCM #Photosynthesis

Career opportunity at the Institut Pasteur in Paris, France They are looking for an experienced researcher with a strong background in synthetic chemistry, medicinal chemistry, chemical biology, and who can take a leadership role in chemistry applied to the life sciences and health

Ariane Briegel@arianebriegel.bsky.social · 3w ago

research.pasteur.fr/en/call/mid-...

After four years, several updates and a handful of CRAN releases, 𝗹𝘁𝗰 𝗰𝗼𝗹𝗼𝗿 𝗽𝗮𝗹𝗲𝘁𝘁𝗲 𝗥-𝗽𝗮𝗰𝗸𝗮𝗴𝗲, reached a version I feel genuinely good about sharing with the community. github.com/loukesio/ltc...

De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging | Science www.science.org/doi/10.1126/...

De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging

Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...

science.org

To put science in Spain into context, the median project is 50k per year. That's basically doing guerilla science 🧪

Jose A. Esteban@jaestebancbm.bsky.social · 3w ago

Muchos ya habréis visto la resolución provisional de los proyectos #PID2025 de la @ageinves.bsky.social Aquí va la distribución. La financiación media por proyecto se ha quedado como el año pasado. Y seguimos con 2/3 de los proyectos con <50 k€ por año. ☹️ www.aei.gob.es/convocatoria...

This one is for everyone interested in bacterial respiration: Zymomonas mobilis is weird. 🧪 It can respirate , but doesn't get any benefits (better growth) from it. This has been know for a while, but here we finally got proper fo and f1 knockouts to further investigate this. 1/13

Investigating the role of FOF1 ATPase in Zymomonas mobilis through deletion of its FO and F1 subcomplexes - Microbial Cell Factories

Zymomonas mobilis has a typical FOF1 ATPase, yet does not exhibit oxidative phosphorylation. In order to investigate the function of the ATPase we sought to delete the FO and the F1 subcomplexes, respectively. Clean mutants could be obtained after selection under aerobic conditions. Growth analysis of the mutants showed that they strictly require oxygen for growth and that the oxygen supply is a factor determining maximal growth rate. This is contrary to the wild type, which grows fastest under anaerobic conditions. In the mutant strains, ethanol remains the main catabolic product; however glucose consumption rates are reduced, and the mutants show a higher sensitivity to low medium pH. Compared to the wild type, the mutants show an increased biomass yield. Our data support the previously proposed regulatory role of the FOF1 ATPase in controlling glycolytic flux, and indicate that the FOF1 ATPase plays an important role in expelling protons from the cytoplasm. In the mutants, this function is taken over by the electron transport chain in the presence of oxygen.

doi.org

🧬 Even Earth's most abundant enzyme makes mistakes. Rubisco fixes CO₂ for nearly all life but wastes ~20% of potential crop yield on a 3-billion-year-old side reaction. We built a microbial sensor that finally makes it visible & tinkerable in living cells. www.biorxiv.org/content/10.6...

Preprints don’t change much after peer review — and are rarely retracted. go.nature.com/4pebHmM

Think preprints are unreliable? Analysis of 70,000 studies might change your mind

Preprints don’t change much after peer review — and are rarely retracted.

go.nature.com

Does Taboo know who Marie Curie was? How am I allowed to say “French scientist who won two Nobel prizes for radiation”?

Professorship Plant Biochemistry. Bielefeld, Germany. #plantscijobs #plantscijob #plantsciencejob www.uni-bielefeld.de/uni/karriere...

Today I confronted myself with a little trauma an visited the site of the former Carlsberg brewery in Copenhagen, my workplace of a student internship back in the days. People were proud of their workplace back then, and the sponsorhip to art and science of their company 1/x

Exploiting #hydrogenase and ribflavin, "indirect" interspecies electron transfer - as a means of quorum sensing - shapes communities of syntrophic bacteria and hydrogenotrophic methanogens. 🧪🍃 Very interesting take on systems biology from Ang Li et al.‼️ doi.org/10.1016/j.wa...

@breakliquid.bsky.social and I are delighted to say our OpenEVO preprint is finally live! An open source hand-made turbidostat that's modular, affordable, and made to be customized. Designed with love for the research community. Enjoy!!!💚 www.biorxiv.org/content/10.6...

OpenEvo: An Open-Source Platform for Automated Evolution and Analysis

Here we introduce OpenEvo, a fully open-source, low-cost turbidostat platform for automated continuous culture and directed evolution experiments. Existing tools are expensive, complex, or lack open-s...

biorxiv.org

Interested in RNA and proteins? Perfect! 😀 We seek to fill a fully funded 3+ years PhD position for a project on pre-mRNA splicing regulation using structural biochemistry in combination with cell biology and bioinformatics. Find more information on our lab's homepage and get in contact via e-mail!

Application deadline this Friday! Hurry up if you want to be my successor. W 3 Professorship for Plant Biotechnology. Freiburg, Germany. #plantscijobs #plantscijob #plantsciencejob uni-freiburg.de/en/job/00005...

We have a funded 4-year wet/dry PhD position (UK applicants) available to work with me at Strathclyde, and Ashleigh Holmes and Sonia Humphris at the James Hutton Institute. Closing date: 3rd August 2026 🧵 www.findaphd.com/phds/project... www.ibioic.com/skills-train... 1/5

PectoCAZy: mining plant pathogens for industrially-relevant enzyme mixtures at University of Strathclyde on FindAPhD.com

PhD Project - PectoCAZy: mining plant pathogens for industrially-relevant enzyme mixtures at University of Strathclyde, listed on FindAPhD.com

findaphd.com

Yes. I had many friends with kids who essentially had to work around their kid's school schedule. And they were very successful. www.nature.com/articles/d41...

Can you actually do a nine-to-five PhD? Nature readers weigh in

Nature readers share their PhD time-management woes.

nature.com