Where biology, chemistry, and physics meet! 🧬🧪⚛️ Explore our Bachelor's and Master's programmes in Nano-Science at the University of Tübingen and shape the future of science. 🔗 Learn more: www.nano-science.uni-tuebingen.de #NanoScience #UniTuebingen #StudyScience #Interdisciplinary #Biophysics

Now in @jxbotany.bsky.social ! Check out our opinion piece on Atomic Force Microscopy #afm in Plant Biomechanic Research: A powerful tool that needs careful handling, interpretation & more research! @Klaus Harter, @moscabiomeclab.bsky.social at @zmbp-tuebingen.bsky.social doi.org/10.1093/jxb/...

Thrilled to share our collab led by Grace Hibshman with the Shipman lab! Type IX retron-Kva2 structure reveals phage detection via an HTH fold, not a primary sequence. We computationally designed triggers that program bacteria cell death, pointing toward designer antimicrobials.

🔬 #JobAlert Interested in doing a PhD with us in #SyntheticBiology on the Reconstitution of Oscillatory Microtubule-Motor Systems? Check shorturl.at/wis5P (note the eligibility criteria) or/and get in touch with us shorturl.at/WmgOD. Deadline: 31 July 2026 #WeAreHiring #AcademicJobs #ScienceJobs

3year funded PhD position is available in my lab starting in October 2026. Please share #phragmoplast,#plant,#cell division,@FAU.de,#biology,

In www.biorxiv.org/content/10.6... Yean Ming Chew & I show that mutating the interPF interface in human MTs can allow them to assemble in GDP. We propose that tubulin molecules are captured indiscriminately at MT tips but then retained only if they can bind stably to a lateral nearest-neighbour.

Now online as an "accepted manuscript" @jxbotany.bsky.social : Our attempt on summarising our current biophysical knowledge of plant kinesins - including look-up tables for all published motor parameters and where to find them academic.oup.com/jxb/advance-...

Plant kinesins: a bottom-up approach – from single molecules to function

Abstract. During land colonisation, plants evolved new microtubule structures that have no functional analogues in opisthokonts, namely animals and fungi.

academic.oup.com

New paper! 🚀 A high-affinity anti- #mNeonGreen #nanobody turns #mNG into a #multifunctional Tag. @nanotag.bsky.social decided to openly share the #nanobody for research use. Not common, but we strongly believe well-defined reagents are key for reproducible science. We hope you find it useful! 💚

A High-Affinity Nanobody Recognizing mNeonGreen Enables Versatile Biochemical, Cellular, and in vivo Applications. by Steffen Frey and team: www.biorxiv.org/content/10.6...

With a motivating push from @christlet.bsky.social I made a new Fiji plugin, CurveMorph. The idea was to create a tool for kymograph generation along the dynamic (bending/shaking) filament shapes (microtubules, cilia, neurites, etc). The logo was made using the plugin. github.com/UU-cellbiolo...

Our latest review is out. We take a deep dive into the human mutations in microtubule motors that drive devastating neurodevelopmental and neurodegenerative diseases. Taking in motor protein biophysics, animal models of disease as well as patient phenotypes. onlinelibrary.wiley.com/doi/full/10....

Happy to share our newest preprint. We developed guidelines and analysis workflows for FLIM Imaging in plants. Multiplexing with spectrally overlapping fluorophores in plants is now possible. Have a look. Any feedback is more than welcome. www.biorxiv.org/content/10.6...

Wormholes do exist....👽

Saishree S. Iyer and Anna Akhmanova @utrechtuniversity.bsky.social review the mechanisms controlling plus-end elongation of centriolar and ciliary #microtubules, revealing shared principles. rupress.org/jcb/article/... #Centrioles #Cilia #Cytoskeleton

Thrilled to see this work published. Thanks to helpful reviewer suggestions, there are some exciting new insights that were not in the preprint (particularly in Figure 4). www.nature.com/articles/s41...

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 3mo ago

The hidden rules behind mRNA transport. A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs. Read more: mrclmb.ac.uk/news-events/... #LMBNews @cellbiol-mrclmb.bsky.social 🧪

👩‍🔬Calling all researchers! Are you interested in working on a project at Physics of Life? 🔬Our new Visitors Program will allow scientists to visit PoL for up to 6 months to pursue an interdisciplinary project, with their travel and accommodation covered. Learn more here and apply: tud.link/nasaw5

Rob Cross @mechanochemistry.org shares his insights on kinesin and microtubule nanomechanics at #DynamicCellVI Rob is the recipient of the @biochemsoc.bsky.social Award for Sustained Excellence 2025. Congratulations!

Come and join us at B CUBE (TU Dresden) as group leader - great environment, lots of Molecular Bioengineering from biochemistry to biophysics around and looking forward to support you in setting up your own research team. Details 👇 datashare.tu-dresden.de/s/XtAFtSy25H.... Deadline 21 May 2026.

B_CUBE_GL_Ad.pdf

Datashare - Provided by ZIH

datashare.tu-dresden.de

Attention #MICROTUBULE fans!! A new TECHNIQUES AND PROCEDURES paper is out at #CYTOSKELETON. Visualizing Specific #Tubulin Isotypes and #Pathogenic Variants in #Cellular Microtubule Arrays. Check out the paper here: onlinelibrary.wiley.com/doi/10.1002/...

Our ExM Atlas of eukaryotes is moving along with more and more images coming in - some featured in nature last month! Culture we’re provided by @ccapoban.bsky.social & Julius Lukeš during visits last year www.nature.com/immersive/d4...

See the intricate worlds of parasites and algae — March’s best science images

The month’s sharpest science shots, selected by Nature’s photo team.

nature.com

I just published: TSL Alumnus wins Biochemical Society Award Mauricio Contreras has been recognised as an exceptional Early Career Researcher by the Biochemical Society. #CelebratingAlumni medium.com/p/tsl-alumnu...

TSL Alumnus wins Biochemical Society Award

FIRST PUBLISHED: 14.04.26 | THE SAINSBURY LABORATORY

medium.com

Make your own PDMS+micromirror device for single-objective light-sheet SMLM: www.biorxiv.org/content/10.6...

"Why is publishing so expensive?" It's a question I hear all the time, so we at @biologists.bsky.social thought we'd try to dispel some of the myths around publishing economics & provide transparency around our costs. Today, we publish editorials in all 5 of our journals - links in the thread below.

Registration deadline for our motors and filaments meeting is tomorrow - not a 1st April joke! Thanks to our generous sponsors supporting sustainable scientific conference organisation @embo.org @biologists.bsky.social we also offer registration for a free livestream, supported by bsky discussions!

A unique opportunity to lead the most wonderful company in scientific publishing (I might be slightly biased here). The Company of Biologists are searching for a CEO. www.inspiredselection.com/jobs/jo00000...

Chief Executive Officer | Inspired Selection

inspiredselection.com

#Neurons rely on molecular motors to deliver proteins to precise locations. Jiang, Ichinose, Hirokawa et al. show that #kinesin-2 motors form heterogeneous assemblies with distinct cargo preferences: A KIF3B-enriched assembly preferentially associates with TRIM46 rupress.org/jcb/article/...

Join us for the next DGZ Focus Workshop, next week Tuesday, organized by Franziska Lautenschläger & Anne Straube, featuring topics around #cytoskeleton and #molecularmotors. Talks by @lilianpaty.bsky.social , Rhoda Hawkins, Roman Podhajecky & Kanako Iwasaki

Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...

Cryo-EM structure of yeast telomerase

YouTube video by MRC Laboratory of Molecular Biology

youtube.com

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 4mo ago

Led by Investigator Scientist @hongmiaohu.bsky.social, @kellythd-nguyen.bsky.social’s group in the LMB’s Structural Studies Division have produced the first ever structure of telomerase from yeast. Read more here: mrclmb.ac.uk/news-events/... #LMBResearch #cryoEM 🧪

Deutschland beteiligt sich an "Open Research Europe" #ORE. Über die Plattform können Wissenschaftler*innen aller deutschen Forschungseinrichtungen ihre Ergebnisse künftig kostenfrei veröffentlichen u. im offenen Verfahren begutachten lassen. Die DFG ist mit der Durchführung beauftragt: sohub.io/rqll

#ServiceNotification SiR-DNA completely blocks Anaphase of hTERT-RPE1 cells during time lapse recordings (every 3min) for mitotic progression analyses at concentrations >/= 5nM (@1h preincubation). No DNA staining with 1nM. Visible staining AND progression beyond Anaphase with 3nM SiR-DNA only.