I sure hope this is fake news! economictimes.indiatimes.com/nri/study/uk...

UK research councils pause applications for major research grants - The Economic Times

Three major UK research councils have temporarily halted applications for several funding programmes, sparking concerns among scientists about potential research spending cuts. The Medical Research Co...

economictimes.indiatimes.com

Every year, I inch further and further towards the southwest of this graph.

Simon Kuestenmacher@simongerman600.bsky.social · 8mo ago

A good family Christmas features all four main characters to maximize drama.

From Sendai to Kyoto: the HFSP Science Summit Japan 2025 connected outstanding scientists and young researchers in a week of collaboration and discovery. 📖 Read the full story → zurl.co/5eYb5 🧪 #sts #HFSPSummitJapan

From an accidental discovery of hidden biology to a new framework to understanding and diagnosing rare disease. Thrilled to share the most recent work from our lab and the amazing Jimmy Ly. wi.mit.edu/news/alterna...

Alternate proteins from the same gene contribute differently to health and rare disease | Whitehead Institute

Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients thro...

wi.mit.edu

Two back-to-back stories on mitosis led by my incredible postdoc @krunovuk.bsky.social at @institutrb.bsky.social, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in @natcomms.nature.com doi.org/10.1038/s414... doi.org/10.1038/s414...

Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵 www.anthropic.com/news/claude-...

Claude for Life Sciences

Discover how Claude accelerates life sciences research with new scientific connectors, skills, and improved performance for drug discovery and clinical work.

anthropic.com

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

Just over one week until this opportunity closes! If you’re an ambitious computational scientist looking for a Postdoc position, apply now

Alexis Barr@alexisbarr.bsky.social · 11mo ago

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

We are looking for our next PhD student to join us 🤩 www.mcclellandlab.com to understand cancer radiation therapy's impact on DNA damage repair and chromosomal instability. Prestigious funding from CRUK RadNet. Please contact me informally - deadline 5th Nov! crukradnet.colcc.ac.uk/phd-students...

Investigating the interplay between DNA damage repair mechanisms, genomic instability and radiotherapy resistance - CRUK RadNet

Investigating the interplay between DNA damage repair mechanisms, genomic instability and radiotherapy resistance Primary supervisor: Sarah McClelland, Queen Mary University of London Secondary superv...

crukradnet.colcc.ac.uk

CRUK Radiation Research City of London Centre @cruk-rrc-col.bsky.social · 10mo ago

Interested in carrying out research in cancer Radiotherapy and Radiobiology? Applications are open now for our PhD programme for 2026 intake! @kingscollegelondon.bsky.social @qmbci.bsky.social @crick.ac.uk @ucl.ac.uk crukradnet.colcc.ac.uk/phd-students...

Fantastic meeting with an excellent line up of speakers. Come join us for the Australian Cell Cycle meeting in Melbourne.

Andrew Deans@genomestability.bsky.social · 10mo ago

Australian Cell Cycle, DNA repair and Telomere meeting draft schedule is now online! Join us with 5 plenary speakers, 16 invited national speakers, 22 selected speakers, 61 poster presenters and lots and lots of fun science. Less than one month to go. australiancellcycle.org/draft-schedu...

@currentbiology.bsky.social has always been one of my favorite journals but I think they have now outdone themselves www.cell.com/current-biol.... And picked up by the @nytimes.com as well! www.nytimes.com/2025/08/18/s...

Periodic excretion patterns of seabirds in flight

Uesaka and Sato report on the excretion patterns of seabirds in the open ocean determined using a rear-facing video logger.

cell.com

As students come back to campus in the UK, 8% of female students are likely to experience rape during their undergraduate years, especially in the first months of their studies. revoltsexualassault.com/wp-content/u...

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

imperial.ac.uk

We're hiring ! Specifically....we are seeking to appoint a creative and motivated Postdoctoral Training Fellow to study how drug resistance emerges in homologous recombination defective (HRD) breast cancers and how this could be targeted. jobs.icr.ac.uk/vacancies/13...

PDTF - Homologous Recombination Defective Cancers ( Profs Chris Lord and Andrew Tutt) in Chelsea | The Institute of Cancer Research

View details and apply for this PDTF - Homologous Recombination Defective Cancers ( Profs Chris Lord and Andrew Tutt) vacancy in Chelsea . Salary: Dependent on relevant Postdoctoral exp...

jobs.icr.ac.uk

Thanks for sharing our work @bladoux.bsky.social (you just made the lead author @marcoenriquez18.bsky.social very happy 😊)

Benoit Ladoux@bladoux.bsky.social · 11mo ago

Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensions | Science Advances www.science.org/doi/10.1126/...

Research is never a solo effort. It takes teamwork. It takes belief. It takes collaboration across disciplines, institutions, and communities. We know what it takes to beat blood cancer. #BloodCancerAwarenessMonth @bloodcanceruk.bsky.social @sussexbcr.bsky.social @sussexcancer.org 🩸

Checkout our latest research in @natcomms.nature.com rdcu.be/eBqBI A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells. A collaboration with Mike Boemo’s team

A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells

Nature Communications - Determining how replication forks move across the human genome is critical for the effective use of agents that target replication stress. Here, the authors present...

rdcu.be

I’m excited to highlight our latest paper, just published in Cell 🎉 We report the existence of a previously uncharacterized signaling pathway that is responsible for activating cell death upon loss of gene expression. 1/n 🧪 www.cell.com/cell/fulltex...

RNA Pol II inhibition activates cell death independently from the loss of transcription

When RNA polymerase II (RNA Pol II) is inhibited, the inhibition is sensed and signaled to mitochondria, leading to programmed cell death independently of the loss of RNA Pol II transcription activity...

cell.com

... and this one too! Again, quite amazing microscopy. Major congrats to Maria + colleagues for getting this story online.

Genome Damage and Stability Centre (GDSC)@gdsc-sussex.bsky.social · 11mo ago

#NEW_PAPER In this study, the Chan Lab uncover the molecular mechanisms by which human cells safeguard centromeric chromatin during mitosis, via tight dynamic control of the Bloom Syndrome complex (BTRR). rdcu.be/eCGxF

Excited to share our new @NatureComms paper! We developed C-604, a selective inhibitor of Greatwall kinase, and discovered that cancer cells' sensitivity to it depends on a simple ratio: B55α/Greatwall expression levels. www.nature.com/articles/s41...

We are pleased to annouce that a 3.5-year PhD position is available in the GDSC, for a project jointly supervised by Prof. Hochegger and Dr. Oliver. For additional details, inc. candidate eligibility, and how to apply: www.sussex.ac.uk/study/fees-f...

Tony Oliver’s and my lab have a joint phd position available to investigate mitotic entry control mechanisms Please forward to prospective students! Thank you url.uk.m.mimecastprotect.com/s/ukMTCoy6DT...

PhD Studentship: Understanding and Targeting Cell Cycle Control in Cancer at University of Sussex

At jobs.ac.uk, you can apply for a PhD Studentship: Understanding and Targeting Cell Cycle Control in Cancer. Explore our diverse range of PhD opportunities today.

url.uk.m.mimecastprotect.com

Delighted to share a chemical-genetic system we developed to rapidly inhibit a serine/threonine phosphatase complex (within secs). This will make it much easier to study #phosphatases. The system is also applicable to other “undruggable” enzymes. www.nature.com/articles/s41...

A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores - Nature Communications

Phosphatase enzymes are challenging to study due to a lack of specific inhibitors. Here, authors develop a chemical-genetic system to inhibit and characterize a major Ser/Thr phosphatase complex, and ...

nature.com

Lovely retrospective for Dan Dennett.

Philosophy Talk@philtalkradio.bsky.social · last yr.

The late Daniel Dennett was born on this date in 1942. After his passing last spring, we put together a special retrospective episode with his friend and admirer, Jenann Ismael from @jhuartssciences.bsky.social: www.philosophytalk.org/shows/daniel... #PhilSky #philosophy

Thanks to the @simplyoncology.bsky.social guys for this opportunity to talk about everything high grade glioma!

John McGrane@jmcgrane.bsky.social · 2y ago

🎙️Out tomorrow on The Simply Oncology Podcast🎙️ We discuss High Grade Gliomas with the superb Professor Anthony Chalmers 🎙️ 🚨Part 1 of 2 and we discuss implications of new molecular profiling on prognosis and treatment options. @simplyoncology.bsky.social @profajchalmers.bsky.social

Interesting 🧵 about publishing in Math. tl;dr: All papers in Math are preprinted. When publishers ask big $ for subscriptions or OA, mathematicians simply say "No thanks, we read these papers already on arXiv." Publishers then force unis to buy Math journals by bundling them with Bio journals.

Pause @ Real Scientists DE@realscientists.de · 2y ago

Mathematik ist ein kleines Feld und hat oft eigene Lösungen, die besser sind als was gemeinhin passiert. Heute zum Abschluss will ich das am Beispiel von #OpenAccess vorführen. Die ganze OA Verschiebung hat der Mathe im wesentlichen Verschlechterungen gebracht. Warum? 🧵

Here is my deep dive into Life, the Universe and Everything with Lex Fridman. Discussions include Astrobiology, Technosignatures, the Physics of Life, Quantum Mechanics and the Philosophy of Science. Big fun 3 hr + conversation. www.youtube.com/watch?v=yhZA...

Adam Frank: Alien Civilizations and the Search for Extraterrestrial Life | Lex Fridman Podcast #455

YouTube video by Lex Fridman

youtube.com

Christmas dumplings.

Book of the year for me!

Announcing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...

Chromosome Segregation and Aneuploidy

Aneuploidy is a hallmark of cancer and developmental disorders such as Down syndrome. Understanding how cells accomplish faithful chromosome segregation and how chromosomal instability (CIN) impacts …

meetings.embo.org