Cette carte est gravissime. Mais elle n'a pas fait la une de l'actualité. Pour moi, l'été 2026 marque un tournant. Après celui de 2022, il devient difficile de ne plus parler de "rupture écologique" ou de "point de non retour" pour une partie des milieux aquatiques français. 1/18

Le cocktail explosif. La 3ème canicule arrive. Et cette fois-ci, sécheresse (historique) et feux se combinent à la chaleur. La canicule va frapper l’Europe de l’Ouest alors que nous ne sommes qu’en début d’été. Et les nouvelles ne sont pas bonnes. Un Thread :

Congrats to my labmates for their beautiful work! They describe a new two-component system modulator, SamT, involved in enterobacterial acid stress response. Make sure to check out the awesome double-hybrid experiment!

Microbial Gene Expression - EGM - CNRS UMR8261 - IBPC@egmresearch.bsky.social · 5mo ago

🚨 Preprint Alert 🚨 New preprint from our research department, in Maude Guillier's team. Congrats to first author Jade Mathis de Fromont and co-authors! To find out about SamT, a modulator of a two-component system in enterobacteriacea, follow the link : doi.org/10.64898/202...

A polymerase ribozyme?! Welcome to the RNA world!

Phil Holliger@philholliger.bsky.social · 7mo ago

New paper from my group in @science.org : "A small polymerase ribozyme that can synthesise itself and its complementary strand" www.science.org/doi/10.1126/... Outstanding work by @edogia.bsky.social

Biochemist/molecular biologist Joan Steitz was born #OTD in 1941. She (& team) figured out how our cells read/use genetic instructions to make proteins. A key person who helped crack the code on RNA—the molecule that acts like a messenger between DNA & and the proteins our bodies need. #WomenInSTEM

Our latest paper on protein expression and mRNA stability is out! academic.oup.com/nar/article/... Check out how to increase your protein output with a simple trick. Congratulations to first author @Anna Lipońska, it was a great collaboration with the Aalberts group. #RNAsky #ribosome #EGM

Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli

Abstract. Protein synthesis efficiency is highly dependent on the messenger RNA (mRNA) coding sequence. Furthermore, there is extensive evidence of a corre

academic.oup.com

🫳 Metastable folding of Bacillus subtilis glmS ribozyme modulates turnover by RNase J1: www.sciencedirect.com/science/arti... #subtiwiki

Metastable folding of Bacillus subtilis glmS ribozyme modulates turnover by RNase J1

Rapid turnover of glmS mRNA in Bacillus subtilis by 5′-3’ exoribonuclease RNase J is essential for feedback regulation of glucosamine-6-phosphate (Glc…

sciencedirect.com

In this study, we highlight the importance of the base composition of the first codons for protein expression. An increased abundance of adenine (A) and a decrease in guanine (G) enhance expression and improve mRNA stability. The mediator of this effect is the ribosome.

Boël Lab@boellab.bsky.social · 8mo ago

Our latest paper on protein expression and mRNA stability is out! academic.oup.com/nar/article/... Check out how to increase your protein output with a simple trick. Congratulations to first author @Anna Lipońska, it was a great collaboration with the Aalberts group. #RNAsky #ribosome #EGM

Are authors fairly judged by assessing the #journals in which their work is published? @bihutchins.bsky.social &co reveal that most influential papers are published in lower tier journals, and more authors would be better recognized with #ArticleLevelMetrics #ALMs @plosbiology.org 🧪 plos.io/4oV58Ed

DusB links tRNA modification with oxydative stress response in V. cholerae! Congrats to @zeynepbaharoglu.bsky.social and colleagues!

Zeynep Baharoglu@zeynepbaharoglu.bsky.social · 9mo ago

Our new paper on DusB’s role in redox metabolism in V. cholerae is now out in @narjournal.bsky.social linking tRNAmodif enzymes and metabolic adaptation. Beyond RNA modification: a tRNA-modifying enzyme shaping oxidative stress resilience and metabolism in V. cholerae #rnasky #rnabiology 😊🦠💫

RNA–RNA interactome approaches provide in vivo evidence for a critical role of the Hfq rim face in sRNA–mRNA pairing url: academic.oup.com/nar/article/...

RNA–RNA interactome approaches provide in vivo evidence for a critical role of the Hfq rim face in sRNA–mRNA pairing

Abstract. Most bacterial small regulatory RNAs (sRNAs) modulate gene expression by forming complementary base pairs with target messenger RNAs (mRNAs), dep

academic.oup.com

An rRNA modification to adapt translation to anaerobic conditions!

Molecular Cell @cp-molcell.bsky.social · 9mo ago

Online Now: Hypoxia-induced ribosomal RNA modifications in the peptidyl-transferase center contribute to anaerobic growth of bacteria Online now:

The EMBO Gold Medal 2025 was awarded to Tanmay Bharat and David Bikard: https://www.embo.org/press-releases/embo-gold-medal-2025-awarded-to-tanmay-bharat-and-david-bikard/ 🧪 At #CellBio2025, the EMBO Gold Medal was handed over to David Bikard in recognition of his pioneering work on #GeneEditing.

Exametabolomics!

Snorre Sulheim@sulheim.bsky.social · 9mo ago

Do you think transporters in E. coli contribute to metabolite release? No? Explore the effect of 66 different transporter knockout mutations on the exometabolome dynamics of ~300 metabolites yourself: keio.unil.ch Teaser: Increased proline in ΔputP #microsky #MEvoSky

Today, Minister-President Markus Söder awarded @jorg-vogel-lab.bsky.social the Bavarian Maximilian Order. Presented every two years, the award recognizes outstanding accomplishments in science & the arts and is regarded as one of the state’s highest honors. Congrats on the “Bavarian Nobel Prize”! 👏🎉

Very cool paper, studying mechanisms (and a toxin) targeting the ribosome, translation initiation and the use of Shine-Dalgarno motifs!

SFM Microbial Pathogenesis@sfmpathogenesis.bsky.social · 10mo ago

Two M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals. A big leap in understanding TB’s survival tricks and new angles for therapies. 📖 shorturl.at/Z8MVX ✍️ @genevauxpierre.bsky.social & coll. #MicroSky

BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:

Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Docto...

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

Communiqué de presse : financement de la recherche publique : la communauté scientifique alerte sur un système à bout de souffle. #veilleESR, @info.gouv.fr @agencerecherche.bsky.social @cnrs.fr @franceuniversites.bsky.social @inserm.fr @inrae-france.bsky.social @enseignementsup-recherche.gouv.fr

Congrats to @mlejars.bsky.social for this really cool publication! Tired of your somewhat easy life doing genetics in E.coli? Make it even way easier with Maxence's method!!

Maxence Lejars@mlejars.bsky.social · 12mo ago

Happy to share the published version of our genetic toolbox, EASY-edit, for simple, flexible and efficient targeted editing in E. coli! Feel free to to try it, we can send strains and plasmids! academic.oup.com/nar/article/...

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters

Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.

science.org

Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!

Many congrats to Ninon Christol from our Microbial Gene Expression research unit, IBPC CNRS, as well as to @maximiliankohl.bsky.social from IBMC at Univ. Strasbourg, for their amazing poster prizes!

Happy to have presented my work at the #microbialRNAs meeting today, with a very active discussion and a beautiful session! Looking forward to more science in the next few days in Strasbourg.

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Beautiful paper on translation start sites and extented SD motifs in Staph. aureus. www.biorxiv.org/content/10.1... Congrats to colleagues in Strasburg univ.!

Extended Shine-Dalgarno motifs govern translation initiation in Staphylococcus aureus

Regulation of translation initiation is central to bacterial adaptation, but species-specific mechanisms remain poorly understood. We present high-resolution mapping of translation start sites in S. a...

biorxiv.org

What a fantastic achievement! Carine Tisné is rewarded the CNRS Silver medal for her structural studies of tRNA modification. We are very proud of her, at the Microbial Gene Expression research department, IBPC! www.insb.cnrs.fr/fr/personne/...

Carine Tisné

insb.cnrs.fr