Frog immunology! This is frog-tastic.

The Journal of Immunology@jimmunol.bsky.social · 3mo ago

According to new data, frog mast cells are distinct from neutrophils and share many features associated with mammalian mast cells, such as degranulation and the release of immune proteins and lipid mediators. Read these evolutionary insights in The JI: https://ow.ly/eccV50YNBbO.

According to new data, frog mast cells are distinct from neutrophils and share many features associated with mammalian mast cells, such as degranulation and the release of immune proteins and lipid mediators. Read these evolutionary insights in The JI: https://ow.ly/eccV50YNBbO.

Are you interested in immunology and have a background in bioinformatics? Come work with my incredible collaborator, Dr. Kristen Pauken, at MD Anderson Cancer Center! See this linkedin post for more details or feel free to reach out! www.linkedin.com/feed/update/...

Postdoctoral Fellow - Immunology at MD Anderson | Kristen Pauken

The Pauken Lab is hiring! In the open postdoctoral fellow position, the Pauken laboratory is specifically recruiting applicants with extensive computational expertise to drive single cell transcripto...

linkedin.com

Thrilled to be honored as one of the 2026 Young Physician Scientist Awards from the @the-asci.org! Looking forward to being back in my old stomping grounds in Chicago!!! @mdanderson.bsky.social

With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.

Fantastic new paper looking at the extrinsic effects of PD-1 loss! Check it out.

Journal of Experimental Medicine@jem.org · last yr.

@kepauken.bsky.social, Markson, Sharpe et al. @harvardmed.bsky.social show that when PD-1–expressing and PD-1 knockout CD8+ T cells are within the same tumor microenvironment, both cell types exhibit similarly enhanced functions. rupress.org/jem/article/...

Congratulations to the 2025 Sabin Family Fellowship recipients, 10 early career researchers recognized for their bold, high-impact cancer research. Thank you to the Sabin Family Fellowship for supporting the next generation of innovators. http://spr.ly/633254IbgR #EndCancer

MD Anderson announces 10th cohort of Andrew Sabin Family Fellows

The University of Texas MD Anderson Cancer Center today announced its 10th cohort of Andrew Sabin Family Fellows, comprised of 10 early career cancer researchers. Created to provide a dedicated source of funding for emerging clinician and scientist leaders, the Sabin Family Fellowship supports groundbreaking research that fuels MD Anderson’s mission to end cancer.

spr.ly

I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer. www.biorxiv.org/content/10.1...

BRAFV600E-Driven Lung Tumorigenesis Requires Ligand-Mediated Activation of ERBB Receptor Signaling

Secretion of ligands of the human epidermal growth factor (EGFR) family of receptors or erythroblastic leukemia viral oncogene family (ERBB1-4) is a feature common to many cancer cells. However, our u...

biorxiv.org

Kicking off our journey on BlueSky! We're excited to share updates and connect with you. Follow us and help us get the word out! For more information about the Center for Immunology, go to our website: immunology.umn.edu

Excited to share this preprint: In trial led by @michaelpelusomd.bsky.social and Steve Deeks, combination immunotherapy=>high rate of HIV control (low VL) after ART pause. @demisandel.bsky.social in our lab found control associated with robust CD8+ T cell proliferation early in response to rebound.

Waggoner Lab@labwaggoner.bsky.social · last yr.

Combination immunotherapy induces post-intervention control of HIV www.researchsquare.com/article/rs-6...

Different injection routes and fluorophores affect anti-CD45.2 antibody leukocyte labeling @jmschenkel.bsky.social @jimmunol.bsky.social @thenatcat.bsky.social doi.org/10.1093/jimm...

I am pleased to announce that our newest story is officially out at @jimmunol.bsky.social ! academic.oup.com/jimmunol/adv... This is an immediate follow up to the lab’s first paper from last year. We again thank @jimmunol.bsky.social for a smooth, efficient, and wonderfully fair review process. 1/n

Our newest article is online @naturecancer.bsky.social A new antibody drug conjugate that doesn’t kill tumor cells but rely on immune system to eradicate cancer. @bettykimmdphd.bsky.social @mdanderson.bsky.social

An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy

Nature Cancer - Schrank et al. report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.

nature.com

My last editorial in @ImmunoHorizons the little @immunologyaai.bsky.social journal that could. In this commentary I discuss some of the challenges facing academia. academic.oup.com/immunohorizo...

Give the grant-writing monkeys another banana

You’re probably familiar with the concept that if you had a million monkeys typing on a million computers for a million years, you would eventually get Sha

academic.oup.com

Super excited to announce that the Joag Lab will officially open at @UW, @SCRI in March 2025! We will study the interplay between memory T cells and stromal, humoral, and innate immunity in mucosal tissues. researcherprofiles.seattlechildrens.org/Vineet.Joag. Hiring a technician and a postdoc!

39 rotations around the sun! And what a year it's been. The lab has doubled in size. We had our first (3!!!) graduate students and post docs join the lab. We had both our first and second lab papers EVER accepted - the first is out in print... so check it out -(journals.aai.org/jimmunol/art...).

Longitudinal Intravascular Antibody Labeling Identified Regulatory T Cell Recruitment as a Therapeutic Target in a Mouse Model of Lung Cancer

Key Points. IV anti-CD45.2 label lasts for 3 days and tracks leukocyte migration to tissue.There is continuous innate and adaptive leukocyte migration in a

journals.aai.org

Attention physician scientists! Are you interested in applying for a K08? Of course you are! I will be part of a NIH broadcasted information session featuring myself and another K08 awardee, as well as a reviewer from a K08 study section in January. See the attached flyer! And please repost!

Best #Nikolaus 🎅! Our paper on how the 🫁 microenvironment can shape #innate immunity against #viruses is out @sciimmunology.bsky.social This was a herculean effort brilliantly led by @pauljbaker.bsky.social who singlehandedly established the model in the lab during the pandemic. 🧪 #Immunosky 1/9

www.nature.com/articles/s41... Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang

Next-generation combination approaches for immune checkpoint therapy - Nature Immunology

In this Review, Sharma and colleagues describe the current landscape of combination therapies and discuss requirements for the development of effective combination strategies.

nature.com