Filopodia on N1E cells (F-actin-labelling) #FluorescenceFriday

Can small extracellular vesicles guide growing axons?🧪 Our new preprint provides evidence that small extracellular vesicle (sEV) secretion regulates axon guidance at a key ventral midline choice point during spinal cord development. www.biorxiv.org/content/10.6... #neuroscience #EVs #axon

Dynamic control of cell state transitions during tissue morphogenesis Elias Barriga et al @eliasbarrigalab.bsky.social review how gene expression, chromatin modifications & microenvironmental biophysical factors contribute to robust coordination of morphogenesis link.springer.com/article/10.1...

Hi! I’m @vitoryang.bsky.social, a PhD candidate studying how cells migrate collectively during development. My work focuses on cytoskeleton dynamics and Rho GTPase signalling, using Drosophila border cells as a genetically tractable in vivo model.

Ever wonder what "information" really means? Here's our new paper, led by @frosas.bsky.social, that lays out the multiple ways the term is used in natural science. rdcu.be/fCDGv

Fernando Rosas@frosas.bsky.social · last mo.

What is information, really? Instead of arguing for a single valid interpretation, we propose a pluralistic view where rigorous alternatives coexist — each with affordances and limits Finally published: “Four faces of information in natural systems” 🧵

I always find it amazing how much review figures or graphical abstracts change over time and with more understanding of the subject. If one slow-cooks instead of AI-generates figures that is.. 🧪🎨

Joachim Fuchs@joachimfuchs.bsky.social · last mo.

How do molecular features of protein complexes allow cells to behave collectively? And what can we learn from collective cell migration in epithelial and mesenchymal cells to understand brain development? These questions motivated our recent review: doi.org/10.1515/hsz-... 🧪🔬🧠 1/10

Only 5 days left to get the amazing Scientific Illustration Inkscape Masterclass at a reduced price. From zero to illustration hero in no time. Check it out myablefy.com/s/biovoxxel/...

Scientific Illustration – Inkscape Masterclass for Life Scientists

Learn to create professional scientific illustrations using Inkscape. This BioVoxxel masterclass covers vector graphics, color theory, and 3D effects for life scientists.

myablefy.com

I've made a video about Fig_Space, the next version of FigureJ. It has nice new features, I hope you like it. youtu.be/bTKcXN4p-JM

FigSpace Fiji plugin demo

YouTube video by jerome mutterer

youtu.be

How do molecular features of protein complexes allow cells to behave collectively? And what can we learn from collective cell migration in epithelial and mesenchymal cells to understand brain development? These questions motivated our recent review: doi.org/10.1515/hsz-... 🧪🔬🧠 1/10

Calling the hive mind: Has anyone encountered an unusually high number of rDNA-associated reads in a 10x v4 scRNA-seq library? We have millions of reads mapping to Drosophila rDNA, multimapping/low MAPQ, with strong enrichment at specific rDNA regions. Curious if others have seen something similar!

How do molecular features of protein complexes allow cells to behave collectively? And what can we learn from collective cell migration in epithelial and mesenchymal cells to understand brain development? These questions motivated our recent review: doi.org/10.1515/hsz-... 🧪🔬🧠 1/10

Doing a Master or PhD and interested in Developmental Biology? Join the free Institut Curie developmental biology course in beautiful Paris this fall! Great speaker lineup, check: training.institut-curie.org/courses/deve... Registration deadline Sept. 18 2026.

New paper 🧵 What if the "landscape" that guides cell differentiation isn't fixed, but is sculpted, in real time, by the very cells moving through it? We call this a 'sandscape' : grains of sand that carve dunes as they move, while the dunes' shape simultaneously steers where the grains go next.

You might have heard about our GitHub repository on #OpenMicroscopy. I finally vibecoded a page that (a) allows to search all entries and (b) generates a new database as soon as items are added on GitHub: hohlbeinlab.github.io/OpenMicrosco... Check it out and comments welcome!

😎 to have this out! --> stay tuned, this is a series about 📊#dataviz for #science 🧪

Nature Methods@natmethods.nature.com · 4mo ago

We are very excited to bring back our popular Points of View column, written by @helenajambor.bsky.social! Check out her first column in our July issue about the usage of color scales in scientific figures. www.nature.com/articles/s41...

Just a couple more days to get your application in! www.biologie.hu-berlin.de/en/groupsite...

Andrew Plested@andrewplested.bsky.social · 5mo ago

Very pleased to announce the 3rd Berlin Single Molecule Biophysics Course, this September 14th-18th. We now include more single molecule microscopy, with @ewerslab.bsky.social and Maximillian Ulbrich joining Jelena Baranovic and Claudio Grosman as tutors. Apply @ bsmbc@icloud.com by 12th June!

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

tl;dr: There never was a paradox of the organism. It was just a mistake about genes. But genetic conflicts do occur and are fascinating. This is also an invitation: if you like the selfish-gene idea, I'd love to hear why. What biological reality does the metaphor capture?

Philip Ball@philipcball.bsky.social · 4mo ago

I have read and enjoyed The Paradox of the Organism by @arvidagren.bsky.social and Manus Patten. I had a lot of thoughts about it, and about selfish genes. Here they are, in a long blog post. homunculusmusic.wordpress.com/2026/05/30/i...

I'm quite tempted! Plasmid cloning in the terminal. Amazing concept and execution from @atinygreencell.bsky.social Love it.... "A live spinner and poll counter prove the search is really running, and Cancel actually stops it." 😂 github.com/Binomica-Lab... #Python #bioinformatics

Sebastian S. Cocioba@atinygreencell.bsky.social · 4mo ago

SPLICECRAFT v1.0 IS LIVE!!!!!!!!!!!! Open your terminal and type in "pipx install splicecraft" if you want to try it out, then spam "splicecraft update" often as I push updates frequently. A labor of love for the community I adore. Enjoy! 💚

Exciting to see this out in its final form! Wonderful work led by @probablycarmen.bsky.social. Want to know why protrusions are better at initiating immune signaling in #Tcells? Look no further. Link to Carmen’s 🧵 on the preprint bsky.app/profile/prob...

The EMBO Journal@embojournal.org · 5mo ago

Revised role for actin-rich protrusions in T-cell activation: @franbottanelli.bsky.social @probablycarmen.bsky.social et al reframe them as sites of enhanced receptor activation by exclusion & clustering dynamics, rather than pre-enrichment of signaling components link.springer.com/article/10.1...

Félix Simon's paper is out in its final form 😍 When we got into (extreme) detail in the temporal and spatial patterning of neuroblasts, Félix asked a simple question "sure, but how does this translate into neuronal cell fate?". www.nature.com/articles/s41...

Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the Drosophila optic lobe - Nature Neuroscience

The authors characterized the spatial origin of Drosophila medulla neurons, completing their previous characterization of the temporal and Notch origins of these neurons and allowing them to correlate...

nature.com

New Hiesinger Lab paper! Melinda Kehribar et al. show how Flies preserve the spatial organization of visual input through axonal projections into the brain. A temporal gradient and two adhesive forces ensure a retinotopic map without a target-derived mechanism. #neurosky #neuroskyence #Drosophila

Target-independent retinotopy in Drosophila / Curr. Biol., Feb. 3, 2026 (Vol. 36, Issue 5)

YouTube video by Cell Press

youtube.com

On the publication bias discourse, I regret that metascience has become a source of decontextualized, low-res, bean-counting-focused `science is in crisis' narratives. It is largely uncurious abt science, desperately lacking in theory & measurement. I'll quote a few takes I liked & add my thoughts🧵

How do cells orchestrate themselves to achieve a directional movement as a group? Hi, I’m @sayukihirano.bsky.social. In this thread, I’ll highlight key mechanisms of how cells communicate with each other to perform directional collective migration.

To all lipid-curious cell biologists: check out this comprehensive overview of lipid-based methods by @gerryhammond.bsky.social and colleagues in @jcb.org — a school of Babel fish for #lipidtime: rupress.org/jcb/article/...

“adoption of AI in science presents what seems to be a paradox: an expansion of individual scientists’ impact but a contraction in collective science’s reach, as AI-augmented work moves collectively towards areas richest in data...

Richard Sever@richardsever.bsky.social · 9mo ago

One of my concerns with AI-assisted research in biology is that we're already looking only in the lamplight and AI incentivizes us to narrow the beam. Seems like it's happening... www.nature.com/articles/s41...

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

bioRxivpreprint@biorxivpreprint.bsky.social · 9mo ago

Evolutionary dynamics of temporal transcription factor series in the insect optic lobe https://www.biorxiv.org/content/10.64898/2026.01.08.698497v1

Won best thesis award with this video! 4 years of research and play in 3 minutes :') youtu.be/so0fPlK1-LM

Smart microscopy, computer vision, and controlling cells with light -- my PhD thesis in 3 minutes

YouTube video by Pertz Lab

youtu.be

📢 Join us, the Haberkern lab, @uni-wuerzburg.de for a postdoc studying neural circuit mechanisms of navigation. You’ll spearheading neurophysiology experiments on our brand new 2P! ⏳ Apply by 28th February 2026 Details: www.haberkernlab.de/docs/ENPostd... #neuroscience #academicjobs #postdoc

We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following: