Tessera

Happy to have contributed to this very interesting work ked/driven by Raid Nisr, Alison McNeilly and Graham Rena (University of Dundee). doi.org/10.1111/apha...

Eric Topol @erictopol.bsky.social · last yr.

Special day for our group @cbmr.science as we celebrate the successful defense of our (first) freshly minted PhD, Dr. Conchita Bringas 🥳 Her thesis was based on characterizing novel #AMPK inhibitors. Special thanks to the great committee @rbdamgaard.bsky.social ,Dave Carling & Lykke Sylow.

The surprising result for a GLP-1 pill (orforglipron) is the magnitude of weight loss in a Phase 3 trial of participants with Type 2 diabetes. For still unexplained reasons, people with diabetes lose much less weight on GLP-1 drugs than those with obesity, w/o diabetes.

Nature@nature.com · last yr.

Th most-cited research papers of all time. A 1951 publication by US biochemist Oliver Lowry in the Journal of Biological Chemistry describing an assay to determine the amount of protein in a solution has been cited more than 350,000 times.

What are the most-cited research papers of all time? https://go.nature.com/3Y4OMOD

Eli Lilly announced positive results from a large clinical trial of its once-daily pill orforglipron in people with type 2 diabetes, while Pfizer announced last week it was halting development of its candidate after signs of liver injury in a trial participant.

Trends in Biochemical Sciences@cp-trendsbiochem.bsky.social · last yr.

Joan was a visionary and inspirational leader, researcher and generous mentor and friend. His legacy will stay forever. @irbbarcelona.org

Online now - a tribute to the memory of Prof. Joan J. Guinovart from Jordi Duran and Matthew Gentry. Prof. Guinovart was a renowned biochemist in the field of glycogen metabolism and known for his leadership in science. (1/4)

Mark Cuban @mcuban.bsky.social · last yr.

President Donald Trump has nominated Susan Monarez, an infectious disease researcher and current acting director of the Centers for Disease Control and Prevention, to become the agency’s permanent leader. scim.ag/425J0xs

Trump’s new CDC pick ‘has her work cut out for her’

Susan Monarez, an expert in biosecurity and infectious disease, strikes some as a sensible choice to head the health agency—but some staffers there have raised concerns

scim.ag

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

BrunetLab @brunetlab.bsky.social · last yr.

Interested in aging? Super excited about this upcoming Keystone meeting!! 🧪🌲🌲 Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨ Joint meeting with the Keystone Innate Immunity meeting! #aging #immunity @keystonesymposia.bsky.social www.keystonesymposia.org/conferences/...

Aging: Immune Function and Organ Health | Keystone Symposia

Join us at the Keystone Symposia on Aging: Immune Function and Organ Health, March 2026, in Banff, with field leaders!

keystonesymposia.org

Anna Krook @annakrook.bsky.social · last yr.

The Strategic Research Programme in Diabetes at Karolinska Institutet and Umeå Univeristy is seeking a Programme Manager (based in Stockholm). More information about the programme is here ki.se/en/srp-diabe... and the link to the position is here ki.varbi.com/en/what:job/... Please repost!

IRB Barcelona@irbbarcelona.org · last yr.

Thank you very much for this initiative and providing us with the opportunity to share our memories and stories. His legacy will stay forever. Visionary and inspirational leader, researcher and generous mentor and friend.

Honoring Dr. Joan Guinovart—a visionary in science and an inspiration to many. Share your memories, stories, and gratitude to celebrate his remarkable legacy. Let’s keep his spirit alive: ➡️ www.irbbarcelona.org/en/guinovart

Eric Topol @erictopol.bsky.social · last yr.

More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention. www.science.org/doi/10.1126/...

Daniel Drucker @danieljdrucker.bsky.social · last yr.

A partner for Petrelintide #obesity www.globenewswire.com/news-release...

Zealand Pharma and Roche enter collaboration and license agreement to co-develop and co-commercialize petrelintide as a future foundational therapy for people with overweight and obesity

Company announcement – No. 4 / 2025 Zealand Pharma and Roche enter collaboration and license agreement to co-develop and co-commercialize petrelintide as...

globenewswire.com

Nature Metabolism@natmetabolism.nature.com · last yr.

"Glycogen drives tumour initiation and progression in lung adenocarcinoma"

Strong presence of the @labsakamoto.bsky.social group members at the Metabolism Day #MD25 @cbmr.science Posters were presented by postdocs Joy & Jordana and by PhD students Maria, Hongling, Conchita & Costanza. #AMPK #TFEB #SIK

A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Learn more: scim.ag/3R59fPe (THREAD 🧵)

Science Advances’ special issue on women’s health highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Articles cover a range of studies from the interplay between menopause and Alzheimer’s risk to the menstrual cycle’s influence on the brain-heart connection. It also describes the opportunities pregnancy provides to research aspects of both physical and mental health. By prioritizing women’s unique physiological and psychological experiences, research can expand the frontiers of knowledge in ways that benefit everyone.

Our group @cbmr.science is now driven by an all women workforce (barring Kei), & we are incredibly fortunate to have these (multi)talented, hard working & generous women who support & elevate each other every day! Happy International Women's Day! #WomensDay2025 #LatePost

Currently, NIH's Center for Scientific Review reviews 66,000 grant applications a year, with panels run by NIH’s separate institutes reviewing the rest. Under a new plan, the institute-run panels will be eliminated, and many of the scientists overseeing them will be laid off. scim.ag/3QP0FUG

NIH will eliminate many peer review panels and lay off some scientists overseeing them

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"The academic structure … makes planning for a family feel like an impossible luxury." In this #ScienceWorkingLife, two postdocs share how, as women in academia, having children can feel impossible—and how talking about it makes them feel less alone. scim.ag/3F60VMt #InternationalWomensDay

As women in academia, having children can feel impossible. Talking about it makes us feel less alone

The struggle is “balancing their careers not just with motherhood, but with what comes before: relationships and planning for a family,” these postdocs write

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Sakamoto Lab@labsakamoto.bsky.social · last yr.

Pleased to share our new preprint describing mechanistic insights and cellular selectivity of the AMPK inhibitor.

New pre-print from the lab @cbmr.science spearheaded by PhD student, Conchita Bringas & in collaboration with @zeqiraj.bsky.social @universityofleeds.bsky.social; providing structure-based molecular insights & cellular actions of the recently identified potent #AMPK inhibitor, BAY-3827.