Dr. Krissy Lyon
@krissylyon.bsky.social
Neuroscientist & astrocyte enthusiast | Postdoc in the Allen lab @SalkInstitute.bsky.social | NINDS K99 |@lclark.bsky.social and Harvard PiN alum | she/her
We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/
My paper is finally out in @natcomms.nature.com ! 🐟🐭🧠 Thankful to the contributors and @annamolofskylab.bsky.social for the support! How does the developing brain clear millions of dying neurons? Read below, if interested. #zebrafish #neuroscience #microglia #devbio @zebrafishrock.bsky.social 1/5
The Orange Cat Brain Atlas is here. 🧠🐈 Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."
Incredibly proud of this paper led by @ossamaghenissa.bsky.social and @mathiasgua.bsky.social titled Basolateral 'Amygdala Astrocytes Encode Anxiety States'. www.cell.com/neuron/fullt... 🧵 below
Basolateral amygdala astrocytes encode anxiety states
Ghenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g...
cell.com
Super stoked to share that I’m starting my lab at UHN @dkjei-uhn.bsky.social / @kbi-uhn.bsky.social and the University of Toronto! If you’re interested in neuron-myelin interactions in circuit maturation and cognition, please reach out - we are hiring! www.oligodendrocyte.org 1/
Xin Lab
Welcome! We study the cellular interactions between neurons and oligodendrocytes, which produce myelin in the central nervous system. Myelination - the process by which oligodendrocytes ensheath neuro...
oligodendrocyte.org
Excited to share that I joined the Institute of Psychiatry and Neuroscience of Paris @ipnp.bsky.social as a group leader! Thank you to FRM and BBRF for the support! My team will study how dedicated neural circuits decode seasonal changes, and drive adaptive behaviors. 🧠 ☀️ ❄️
Very excited to share our new manuscript – published today! Why are PIEZO1 and PIEZO2 are tuned to transduce different types of mechanical force? I was lucky to work with some extraordinary colleagues to begin to figure out why. www.nature.com/articles/s41... An overview of the results below ⬇️ ⬇️
The molecular basis of force selectivity by PIEZO2 - Nature
PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.
nature.com
PIEZO2—unlike PIEZO1—is tethered to the actin cytoskeleton, enabling sensory neurons to detect localized mechanical forces such as light touch. Findings reported in @nature.com by @ericmulhall.bsky.social from @ardemp.bskyverified.social's lab link nanometer-scale imaging to sensory function.
A new clue to how the body detects physical force
scripps.edu
New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function. www.nature.com/articles/s41...
The molecular basis of force selectivity by PIEZO2
Nature - PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.
nature.com
I am SO incredibly excited to announce the launch of a global list of Inspiring Black Scientists. You can use this list to nominate and connect with researchers. Please share and join us in highlighting these outstanding scientists for #BlackHistoryMonth and beyond! www.wiley.com/en-us/resear...
Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers. Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
US science after a year of Trump: what has been lost and what remains
A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.
nature.com
If you are submitting an NIH grant in February, you will be required to use SciENcv to prepare you biosketch. IT IS MUCH WORSE THAN YOU CAN POSSIBLY IMAGINE. Set aside *at least* 4 hours just to transfer an existing an biosketch into SciENcv.
Astrocytes put the brakes on brain plasticity in mice by secreting the protein CCN1 to stabilize existing circuitry, a Nature study shows. By Holly Barker #neuroskyence www.thetransmitter.org/astrocytes/a...
Astrocytes stabilize circuits in adult mouse brain
The glial cells secrete a protein that suppresses plasticity post-development.
thetransmitter.org
Our story on mechanosensation in baroreceptor cells of the kidney is finally out! Well worth the wait on this project we began in 2020 that turned into a massive collaborative effort within the kidney field. 🫘 www.sciencedirect.com:5037/science/arti...
sciencedirect.com
If you missed our Minisymposium at #SfN2025, you can still catch up with some of the topics by reading our new review: www.jneurosci.org/content/45/4... Also, got the printed version of this paper (and many more)🤩 @sfn.org
We are definitely going to sell out of laser cut brain earrings early in the conference!!! Warning! #SfN25
WOW! 372 "astrocyte" presentations this year at #SfN2023 @SfNTweets Not enough talks - let's work on this for 2024. Full roundup below. I am SURE I have missed some, so please reply with more! Daily session roundups to come for each session. See you all soon. #SocietyForGlia
#SfN25 is here!!! I am looking forward to giving a talk in the ‘Astrocytes in neuronal function and dysfunction’ nanosymposium on Monday afternoon, come by!
So happy to share that many of my NINDS colleagues will be attending SfN!! Learn more and find them here www.ninds.nih.gov/news-events/...
ninds.nih.gov
If you are viewing our social media, seeing our new Webpage, looking at our great partners, the work we do together, please consider telling a friend or a philanthropist org. Here's why what we do is so important, not only for the Indigenous, but now everyone's data www.youtube.com/watch?v=eebH...
The Native BioData Consortium: A Beginning
YouTube video by Native BioData Consortium
youtube.com
If you will be at #SfN25 next week, please join us for a professional development workshop ‘Navigating your career roadmap in a changing landscape’ on Monday from 12-2. Led by THE Dr. Michelle Jones-London. Please share with your lab and anyone you think would benefit!
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!
Edward Kravitz, a Harvard biochemist who proved GABA's inhibitory power, passed away last month. He will "be remembered for his humanity, for his social conscience and his desire to help those less fortunate than he,” says Ronald Harris-Warrick. By @claudia-lopez.bsky.social bit.ly/479Ggmo
Remembering GABA pioneer Edward Kravitz
The biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is inhibitory.
bit.ly
It is based on a word cloud from the titles of the 197 MOSAIC grantee projects. I had it made if I have testify in the grant delay trial but it was perfect for this occasion. Who needs PowerPoint?
Theresa Kim, PhD, MS@tyk314.net · 10mo agoI love the tie you wore.
Lab’s 1st preprint! Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate. @cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation. He is on the job market!
Çağrı Çevrim@cagricevrim.bsky.social · 10mo agoI’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵
A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails. Not an easy job under the best of circumstances and right now it's the pits. Thank you!
