I vote for the normalization of the term "in vitreo" for cryoEM structures to sooth the brains of cell biologists that insist the cryoEM structure is not the native structure. (It is as close as we can get). This should both satisfy their thirst and aggravate them bc it looks like "in vitro"

Archer's Iconic 'Uh, Phrasing?' Moment

ALT: Archer's Iconic 'Uh, Phrasing?' Moment

static.klipy.com

Come join us! 🔬🐣 The Piacentino Lab at Johns Hopkins @hopkinsmedicine.bsky.social is recruiting a postdoc to study membrane lipids, cell migration, and invasion in neural crest and embryonic models! @socdevbio.bsky.social @ascbiology.bsky.social #devbiol #cellbio #lipids

It’s time for the World Cup final with one of the greatest footballers that may be playing his last cup So time for a short thread on a link between Messi and an intrinsically disordered protein. 1/n

Holy COW. Text analysis of comments on the OMB rule: overwhelming opposition, overwhelmingly not form letters. (But 9 in 10 comments supporting the rule ARE form responses, LOL) Whatever happens next, folks have stepped up.

Karen R. Lips@karenrlips.bsky.social · 3w ago

techpolicy.press/the-public-r...

Biophysics used to be the field of applying mathematical principles of physics to biology, but biology has largely fallen in line with this. Biophysics today is more about bridging fields and scrutinizing methods across disciplines. Bio(Ph)ysics it's what's for breakfast!

Wow. I love papers like this where you start off thinking “what? Sounds fishy” and then the data are so convincing and the paper so well written that is all so clear that you are blown away. Cells have a little aerial to allow them to move toward the anode!!! Galvanin! #PureScience #biophysics

Galvanin (TMEM154) is an electric-field sensor for directed cell migration: Cell www.cell.com/cell/fulltex...

🏆 Introducing the inaugural Suzanne Eaton Awards for Physics of Life! We're thrilled to announce the 2026 recipients: L. Mahadevan @harvard.edu and Anna Erzberger @embl.org. 👨‍🔬Both scientists will give award lectures on 20. November, more info to follow ➡️Read our announcement here: tud.link/cjm8t2

Come join the new Novo Nordisk Foundation Center for Protein Design as a group leader Cool science in a great scientific environment in wonderful and very family friendly Copenhagen There are two positions that can either be at TT assistant or associate prof level employment.ku.dk/tenure-track...

Tenure-track Assistant Professor or Associate Professor of De novo Protein Design

The Novo Nordisk Foundation Center for Protein Design at the University of Copenhagen seeks to appoint two new group leaders in de novo protein design from 1 February 2027 or as soon as possible thereafter. These positions will be at the Assistant or Associate Professor level and associated with the Department of Biology (Faculty of Science) or the Department of Drug Design and Pharmacology (Faculty of Health and Medical Sciences).

employment.ku.dk

📣 Hear! Hear! 🦋 Behold this Bluetorial on a cool paper written with my PhD student Nathaniel Wesnak 🧪 If you want to dive into the rabbit hole of lipid flop-flop and its description as a stochastic process—here’s your TEASER TRAILER on some flippin’ awesome work: doi.org/10.1063/5.03... 1/26

Stochastic process description of lipid flip-flop

Since lipid bilayers are self-assembled macroscopic aggregates, their constituent lipid molecules can spontaneously transition between the two leaflets. This so

doi.org

Welcome to the official Bluesky account of the Weizmann Institute of Science. Here we share scientific discoveries, research news, and stories from our scientists.

Any1 is a #phospholipid scramblase involved in #endosome biogenesis. From Jieqiong Gao, Christian Ungermann and colleagues: rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...

Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P2. From Jing Ze Wu, Sergio Grinstein, Spencer Freeman @spencerfreeman.bsky.social and colleagues: rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...

What a trove! Brief, factual one paragraph summaries of science news and one-liners for actual articles with links. No opinions, or 'discussion' just quick snippets of news, article links and general happenings in science, all with sources and direct links. #science #nature #academics #world

Mike Shanahan@mikeshanahan.bsky.social · 2mo ago

Just published: The new edition of my newsletter for journalists (and anyone else) interested in biodiversity, the ecological crisis and nature-based solutions to climate change. 🌏🧪 thenaturebeat.substack.com/p/nature-bea...

This looks like a very useful tool for everyone who regularly simulates complex Martini membranes! Thanks to @fabiololicato.com and his team for spearheading this effort!

Fabio Lolicato@fabiololicato.com · 2mo ago

As part of @sfb1638.bsky.social in 𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞 𝐑𝐞𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠, we are committed to developing computational tools that make complex membrane simulations more accessible, reproducible, and scalable for the scientific community. Today, we are happy to share the public release of 𝐎𝐩𝐞𝐧𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐁𝐮𝐢𝐥𝐝𝐞𝐫 v1.2.1

🧪⚛️ Our paper is finally published in Phys Rev Research! doi.org/10.1103/cnfz... Can cells make decisions using equilibrium physical principles, without resorting to irreversible, energy-consuming signaling cascades? We say yes, with the help of self-assembling membrane proteins! 🧵(1/7)

I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇

Seeking a post-doc for the LaJoie lab at the Human Technopole, Milan, Italy! We are looking for candidates from the fields of biochemistry, cell biology, and proteomics, who are interested in studying protein interactions of the nucleus 🤓 lnkd.in/dTG2CgXF

New PhD opportunity in my lab📣! The PhD studentship* will be embedded in a broader project looking at glioblastoma from a mechanobiological angle, funded by a recently granted Springboard award from the @acmedsci.bsky.social 🙏. *only home student fees covered 👉 www.findaphd.com/phds/project...

Leveraging mechanobiology for the dissection of stem-like properties and therapeutic resistance potential in glioblastoma cells at University of Strathclyde on FindAPhD.com

PhD Project - Leveraging mechanobiology for the dissection of stem-like properties and therapeutic resistance potential in glioblastoma cells at University of Strathclyde, listed on FindAPhD.com

findaphd.com

The struggle is real

Pretty cool!! pubs.acs.org/doi/10.1021/... Last year, we showed that membranes can be asymmetric in an unexpected way: more phospholipids on one side than the other, balanced by cholesterol asymmetry. Here, Bogdanov et al show similar in EColi, with DAG doing cholesterol's flippy-buffering job

Dark Side of Escherichia coli Biogenic Inner Membrane: Overabundance of Three Main Phospholipids on Cytoplasmic Leaflet

Transmembrane (TM) asymmetry of glycerophospholipids in the plasma membrane is well established, yet still a complex and evolving area of study regarding the exact mechanisms, magnitude, and compositi...

pubs.acs.org

Scientifically, a raven has 17 primary wing feathers, the big ones at the end of the wing. They are called pinion feathers. A crow has 16. So, the difference between a raven and a crow is only a matter of a pinion.

Black Bird's Flowing Walk

ALT: Black Bird's Flowing Walk

static.klipy.com

Agree with this long thread on (mostly) strengths and (very few) weaknesses of present NIH grant peer review process

Christos Constantinidis@cconstan.bsky.social · 2mo ago

I just completed my service in my NIH study section. Some thoughts - with the disclaimer that these are personal, subjective impressions and do not reflect the opinion of any official body. Other than the one attached to my head. (1/10)

#Academia #PostdocLife #Science #HPS #BioSky How do you deal with complete lack of motivation and writers block?

Doing a linear stretch on these images shows how dramatic the "edits" were, revealing the deception in clear terms. This should be a complete scandal for Thermo Fisher and more people in the biosciences should be talking about it.

Reese Richardson@reeserichardson.bsky.social · 2mo ago

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

Wow. I always suspected those blots (and the antibodies behind them) were crap, but this is far beyond the pail

Reese Richardson@reeserichardson.bsky.social · 2mo ago

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

Scientific Streisand Effect

Michael D. Green, PhD@michaeldgreen.phd · 2mo ago

If the goal was to not let them share reprints of an editorial, maybe having the police escort them out was not the best choice 😭😭 @altmetric.com www.altmetric.com/details/1954...

I just learned that OMB is required to respond to every comment on the anti-peer-review rule. So that means our comments really matter, at the very least by gumming up the gears. Send your comment today.

@bowprow.bsky.social · 2mo ago

PLEASE submit a public comment opposing this rule change during the comment period. Do not let this go unchallenged. Urge your friends and associates to do the same. www.npr.org/2026/06/03/n...

Literally, life giving you lemons. Its free fruit! So much lemonade and great pasta dishes to be made!

Binfire Era@binfire.bsky.social · 2mo ago

LET WOMEN HAVE HOBBIES

Soooo annoying!! Did they do this on purpose?!?

Philip Ball@philipcball.bsky.social · 2mo ago

Anyone else finding that PubMed just gets stuck in endless rounds of Captcha demands these days?

NIH's Stadtman Investigator Program is back in 2026! As a Stadtman tenure-tracker myself, I cannot emphasize how important this program has been to the establishment of our lab in the intramural world. Take a look, ask me any questions you may have, and apply!