🚨NEW PAPER 🚨 "Deconstructing empirical fitness seascapes across scales of granularity" published in #G3 (@genetics-gsa.bsky.social) 1/2 The fitness landscape has been among the most influential instruments in evolutionary theory for nearly a century. But we often treat them as fixed and static.

MEEHubs2026 is underway! We had a great start in the first two sessions with Zurich and Manchester hosting some excellent talks! It's not too late to join us virtually via last-minute registration: meehubs.org #MEEHubs2026

What makes human guts and coral reefs similar? Here is a blog post with some thoughts on ecosystem stability, stress, and microbiome, following a fresh pre-print by Marko Terzin et al: merenlab.org/blog/coral-r...

From coral reefs to human guts: stress is stress

Reefs and colons share no taxa, no host, no timescale, but they report stress the same way, which tells us where NOT to look for solutions.

merenlab.org

🚨publication alert: Collateral effects of antibiotic resistance in Campylobacter jejuni - academic.oup.com/femsle/artic...

Collateral effects of antibiotic resistance in Campylobacter jejuni

Collateral effects in antibiotic sensitivity related to antibiotic resistance in Campylobacter jejuni.

academic.oup.com

2. If you've seen this before, a single brain metastasis with an unknown primary, we want your instinct. Assume we haven't heard of what you're about to suggest. 3. Introductions. Doctors, researchers, labs, clinical trials, anyone working on cancer of unknown primary.

Beautiful work (Petrungaro, Bollenbach lab) on evo trajectories toward abx resistance (E. coli). Goes beyond many other studies in its attention to the experimental setup (identical selective pressure across all lines). I strongly recommend reading the entire paper! www.nature.com/articles/s41...

Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance - Nature Communications

Antibiotic resistance can evolve through the combination of factors but the predictability of this is unclear. Here, the authors used high-throughput evolution experiments to reveal that antibiotic re...

nature.com

Lavendelvloer, toch anders dan een pindakaasvloer.

Andy Nishimoto from the Rosch lab at St. Jude led this massive project to evolve Spn in mice across 10 antibiotics and 3 immune states. Shockingly, classic resistance almost never evolved because it was too costly for fitness in the face of host immunity. www.sciencedirect.com/science/arti...

Een maandje geleden werd Nyke Slawik vd Grüne nog met extreem rechts gelach onthaald toen ze vroeg om meer bescherming van Queer mensen. Na de aanslag gisteren in Berlijn is heel rechts ineens Altijd voorvechter van lhbtq rechten. 🤮 In NL zelfde laken een pak! Met hun aanvallen op woke. #Pride

Grüne im Bundestag@gruene-bundestag.de · last mo.

Die zunehmende Gewalt gegen queere Menschen ist ein Problem für die ganze Gesellschaft. Sie trifft den demokratischen Zusammenhalt. Anstatt Streichorgien bei Bundesprogrammen, die Demokratie & queeres Leben schützen, fordern wir eine aktive Rolle der Bundesregierung gegen Gewalt an queeren Menschen!

Mooi stuk! Lees dit artikel op de Volkskrant www.volkskrant.nl/wetenschap/w...

Waarom Nederlandse boeren de wereld jaloers maken met hun antibioticabeleid

Het gebruik van antibiotica in de veeteelt is in Nederland sinds 2009 met driekwart gedaald. Hoe is dat gelukt? Door samenwerking tussen overheid, veehouders en dierenartsen, vertelt hoogleraar Jaap W...

volkskrant.nl

Holiday in the climate emergency. No that’s not AI or edited, just a snapshot I just took with my phone on Lacanau beach in France. What future will this boy grow up in? It is in our hands, but time is running out.

🚨New Pre-print Really excited to see this manuscript out. While short, this was a lot of work with troubleshooting and optimisation at all stages and will, hopefully, be the start out groups major focus. Microbial evolution studies..(1/7) #MicroSky #UTISky www.biorxiv.org/content/10.6...

In vitro evolution of uropathogenic Escherichia coli to fosfomycin resistance in a 3D cultured human bladder microtissue model

In vitro studies of antimicrobial resistance (AMR) using laboratory growth media produce important, fundamental information. However, their inability to more closely replicate the in vivo environment ...

biorxiv.org

Glad to have contributed to this project on something often overlooked in toxicology: combination effects. Gut bacteria face many compounds at once. We found >100 interactions between sweeteners and co-consumed compounds, with consequences in bacteria physiology and genetic targets. Check it out:

Sonja Blasche@sonjablasche.bsky.social · 3w ago

Our article "Common xenobiotics modulate gut microbial responses to low‑calorie sweeteners in vitro" is out! link.springer.com/article/10.1... With @kiranrpatil.bsky.social, @indraroux.bsky.social, @rbradley.bsky.social, @skamrad.bsky.social, @simonemozzachiodi.bsky.social, @itsbinir.bsky.social.

Je kunt wopkes uit #shell halen maar shell niet uit de wopkes.

Omnicrisis@sybren.bsky.social · 3w ago

Heel Europa gewikkeld in een extreme hittegolf, extreme droogte in Nederland, een van de belangrijkste beleidsinstrumenten voor verduurzaming wordt afgezwakt en dan is dit de kop van de @nieuws.nos.nl We hebben journalistiek nodig die de macht controleert, ipv kopieert.

Another holiday period, another flooding of the lab. 😫

This is brilliant . The Peel Sessions playlist . Over 2000 different sessions youtube.com/playlist?lis...

John Peel Sessions - YouTube

youtube.com

Huh. Dovetails nicely with the point that "AI" is a labor issue, actually.

Benjamín Schultz-Figueroa@benjaminschultzfig.bsky.social · 3w ago

A really interesting piece on reducing AI cheating in the classroom from a Professor of English and former Dean of Humanities at University of Utah. The solutions? Smaller classes, lower teaching loads for faculty, and in-person classes.

Is inderdaad wel even een dingetje zo'n brug die vervangen moet worden. Uitzonderlijk? Mweh. Sinds 2015(!!) ligt immers de brug tussen Groningen en Leer eruit. Just saying... www.nu.nl/binnenland/6...

Bijna jaar geen treinen tussen Alphen aan den Rijn en Bodegraven: 'Uitzonderlijk'

Het treinverkeer tussen Alphen aan den Rijn en Bodegraven ligt vanaf oktober negen maanden stil. Dat heeft te maken met de vervanging van de spoorbrug over de rivier de Gouwe.

nu.nl

Very proud of this preprint out of my lab, our first (of hopefully many) host-microbe spatial transcriptomics paper. www.biorxiv.org/content/10.6... Amazing insights into P. aeruginosa biology and chronic airway disease @cysticfibrosis.org.uk @sangerinstitute.bsky.social @asthmaandlung.org.uk

Herinnert me aan het koffie-olie-onderzoek waarvoor ik (jaaaaren geleden) proefpersoon was. Naast dat het enorm ranzig was, bleek het ongezond... www.nu.nl/gezondheid/6...

Veel mensen die cafeïnesupplementen gebruiken ervaren klachten

Bijna 70 procent van de gebruikers van pure cafeïnesupplementen ervaart klachten als trillen, hoofdpijn, misselijkheid, slapeloosheid en duizeligheid. Dat blijkt uit onderzoek van toezichthouder NVWA.

nu.nl

Misschien 'onderzoeken' ook gewoon tussen aanhalingstekens plaatsen. Peer reviewed observationeel onderzoek liet zien dat het virus zich via de lucht verspreide niet Maurice zijn bij elkaar gegooglende portfolio.

NRC@nrc.nl · 4w ago

Maurice de Hond werd met zijn onderzoeken voortdurend ‘genegeerd’ door OMT en kabinet

Intrahost mutational dynamics parallel long-term #genomeEvolution in #endosymbionts by @symboevo.bsky.social & Younghwan Kwak doi.org/10.1093/molb... #SymbioSky

Intrahost mutational dynamics parallel long-term genome evolution in endosymbionts

Abstract. Obligate endosymbionts of insects undergo extreme genome evolution, marked by accelerated molecular evolution, severe base-pair compositional bia

doi.org

“The catheterized urinary tract represents a novel ecosystem that is resilient to disruption by catheter changes but susceptible to antibiotic perturbation.” Longitudinal loveliness! New preprint from @chelsamicro.bsky.social lab - nice work Chelsie & team! #UTISky #IDSky #UTI #CAUTI

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 4w ago

Optimized Urine Metagenomic Methods Reveal Longitudinal Microbial Community Dynamics and Predictors of Transition from Asymptomatic Colonization to CAUTI https://www.biorxiv.org/content/10.64898/2026.07.06.736792v1

[🚨] Publication alert! Years of hard work is now published in @pnas.org - www.pnas.org/doi/full/10.... It's not everyday that a novel biosynthetic intermediate is identified in bacteria, so this warrants a short summary below [👇] 1/7

Optimized Urine Metagenomic Methods Reveal Longitudinal Microbial Community Dynamics and Predictors of Transition from Asymptomatic Colonization to CAUTI https://www.biorxiv.org/content/10.64898/2026.07.06.736792v1

Happy to announce that a new opinion paper of our group just came out: A conceptual framework to dissect emergent functions in microbial communities with @swagatika.bsky.social @sharvari27.bsky.social @anjanaprasad.bsky.social @palshubharthi.bsky.social www.sciencedirect.com/science/arti...

A conceptual framework to dissect emergent functions in microbial communities

Microbial communities play vital roles in diverse ecosystems and are key drivers of numerous industrial or health-related applications. In many cases,…

sciencedirect.com

Of Groningen! In de winter was die 5 graden kouder niet optimaal, maar deze zomer voelt dat heerlijk. www.nu.nl/binnenland/6...

Vakantie zonder extreme hitte? Overweeg de Alpen of de Noord-Duitse kust

Meer vakantiegangers zoeken naar plekken waar de hitte meevalt nu populaire vakantiegebieden als Frankrijk en Spanje steeds vaker te maken hebben met extreme temperaturen. Nederlanders gaan nu vaker n...

nu.nl

This is possibly the best thing I have read on Bluesky since I joined a few years ago. It is that on-point. What we are observing isn't "polarization", it's "radicalization". This can be applied not just to politics, but also many other things in the public discourse - COVID being one close to me.

Petter Törnberg@pettertornberg.com · 4w ago

‘Polarization’ has become the master concept for diagnosing our current democratic crisis. But this is not polarization. It is the radicalization of the political right. By misdiagnosing it, we risk becoming complicit in the crisis. 🧵 Just out in Perspectives on Politics doi.org/10.1017/S153...

How do #bacteria evolve resistance to antibiotics ? This Essay by @craigmaclean.bskyb.social &co argues that the evolution of #AntibioticResistance is catalyzed by ‘resistance potentiators’ that accelerate evolution in a trait-specific manner. 🧪 #AcademicSky @biology.ox.ac.uk plos.io/4flYKnF

WAAROM moet een bezoekerscentrum van staatsbosbeheer rEnDaBeL zijn? Kap met stomme bedrijven maken van dingen die geen stomme bedrijven zijn.

Staatsbosbeheer wil alle bezoekerscentra sluiten: 'Prioriteit bij natuurbeheer'

De zeven buitencentra ontvangen jaarlijks zo'n 1,3 miljoen bezoekers, maar zijn niet rendabel.

nos.nl