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Markus Mukenhirn

@markusmukenhirn.bsky.social

Post-Doc @katjaroeper.bsky.social lab @pdncambridge.bsky.social Interested in kidney organoids and lumen formation; Former @honigmann_lab, @biotec-tud.bsky.social, @cmcb-tud.bsky.social,@mpicbg.bsky.social and @boulantlab

102 Posts2078 Follower4315 Folgt
Cell - a Cell Press journal@cp-cell.bsky.social · 7d ago

Now online! Basement membrane turnover controls cell shape

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane adapts by measuring collagen turnover. We find that perlecan, another basement membrane protein, regulates collagen turnover to control organ shape.

dlvr.it

Yanlan Mao@yanlanmao.bsky.social · 6d ago

This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...

cell.com

Ulrich Schwarz@ulrichschwarz.bsky.social · last wk.

📢Paper alert📢 Now out in @natcomms.nature.com: malaria parasites in infected red blood cells 🦟🔴 divide asynchronously due to a limiting replication resource🧬. Another great collaboration within #SFB1129 👍 Read our open access paper here: doi.org/10.1038/s414...

Competitive resource allocation drives asynchronous and rapid nuclear multiplication in the malaria parasite - Nature Communications

Within red blood cells, Plasmodium falciparum forms cells with multiple nuclei that replicate asynchronously despite residing in a shared cytoplasm. In this study, the authors developed a biophysical ...

doi.org

Jacob (Yaqub) Hanna - يعقوب حنا@jacob-hanna.bsky.social · last wk.

Enjoyed r summarizing this important & reproducible (yes we tried it) paper on how DMSO is sufficient to induce human balstoids from human naive PSCs, emphasizing (again) the great importance cell state has on embryo models formed. Congrat to Mo Li group & @KAUST . www.nature.com/articles/s41...

Signaling-independent boosting of human blastoid formation - Cell Research

Cell Research - Signaling-independent boosting of human blastoid formation

nature.com

MadScientist@mads100tist.bsky.social · 2w ago

Further context: she is the reason firefighters didn't have the means to tackle the fires. She is a climate change denier, too. She is a cancer to the region. She is a modern Thatcher.

Kathleen Bachynski@bachynski.bsky.social · 2w ago

“The president of the Madrid region, Isabel Díaz Ayuso, said on Sunday that the full scale of the devastation was only starting to emerge after firefighters slowed the advance of the wildfires overnight. More than 22,000 hectares, or about 54,300 acres, have been burned across the region, she said”

Mark Peifer (He, him)@peiferlabunc.bsky.social · 2w ago

Tissue remodeling often involves removing cells by extrusion, to eliminate dead cells, unhealthy cells or even to change tissue shape. Read this wonderful thread highlighting some of the papers that advanced our understanding of this key process. 🧪

epithelial mechanics fan club@epimechfc.bsky.social · 2w ago

How do tissues safely remove cells? Join me, @marija-matejcic.bsky.social in this perspective on the past, present and future of epithelial cell extrusion 🧵 0/16

Janosch Dahmen@janoschdahmenmdb.de · 2w ago

1/x Über Leihmutterschaft - insbesondere als kommerzielles Modell wie in den USA - wurde die letzten Tage viel diskutiert. Aus Sicht als Arzt ein Thread zum Zusammenspiel von medizinischen, juristischen und ethischen Implikationen.

Jesse Veenvliet@jesseveenvliet.bsky.social · 4w ago

Just approved an order for standard lab consumables. Prices have nearly doubled since starting the lab. Meanwhile, the bar for publishing keeps rising, requiring ever more costly experiments, while grant budgets barely changed. Hard to see how this is a sustainable trajectory for academic research.

Mark Peifer (He, him)@peiferlabunc.bsky.social · last mo.

Multi-ciliated cells drive many key events, including, for example, expelling pathogens and debris from our lung airways. @raghavan-thiaga.bsky.social Provides a great introduction to the cell biology behind this, and the many unanswered questions. Plus lovely images!! Check it out. 🧪

epithelial mechanics fan club@epimechfc.bsky.social · last mo.

From single-celled organisms to ciliated epithelia in metazoans, precise positioning of basal bodies (BBs), which anchor motile cilia, is essential for generating fluid flows. Here, I, @raghavan-thiaga.bsky.social, will take you on a brief tour of how cells build this spatial organization.

Matthew Freeman@mjafreeman.bsky.social · last mo.

The awesome trio of @lmescu.bsky.social @fpichaud.bsky.social and Fernando Casares (and their teams) are on fire Fly eyes represent 'programmable metamaterials'; human engineering principles pre-exist in biology www.nature.com/articles/s41...

A natural programmable metamaterial controls 3D curvature of compound eyes - Nature Communications

This article uncovers a natural, programmable metamaterial in the developing Drosophila eye. The precise 3D curvature of the adult compound eye is programmed during development by a microscopic, 2D tr...

nature.com

@paveltomancak.bsky.social · last mo.

I missed the discussion around @qedscience.bsky.social ranking release. My take: I tried it on one of my published preprints. It did catch the major gap that we are aware of. The suggested solution was unusable. My impression (n=1) is that its feedback is internally consistent with the paper,...