Congratulations to PMI student @catmphelps.bsky.social from the @meisellab.bsky.social on her upcoming PhD thesis defense! 🙌 🎉

I’m truly honored and deeply grateful to receive the Young Investigator Award from the SMI. Thanks to my mentors, collaborators, trainees, and everyone who has supported our work. I’m excited to continue exploring how the intestinal microbiome shapes mucosal immunity.

Pitt Department of Immunology@pitt-immunology.bsky.social · 3w ago

Congratulations to Reinhard Hinterleitner (@rh-lab.bsky.social) on receiving the @societymucosalimm.bsky.social Young Investigator Award! #ICMI2026 Learn more about this award and Dr. Hinterleitner's research: www.immunology.pitt.edu/news/reinhar...

Congratulations to Victor S. Cortez & @catmphelps.bsky.social, grad student in the @meisellab.bsky.social, on receiving awards from @cytokinesociety.bsky.social. They will both give talks at #Cytokines2026. Read more: www.immunology.pitt.edu/news/pitt-im...

Now in Cancer Discovery @aacrjournals.bsky.social: Tumor Microbial Burden Drives Immune Responses via Regulation of Interferon Signaling - by Haoyue Liu, Jeong-Hoon Jang, Fuduan Peng, Hajar Rajaei, @linghua-wang.bsky.social , Luis Diaz, Florencia McAllister, and colleagues doi.org/10.1158/2159...

New review in @cp-immunity.bsky.social by @meisellab.bsky.social & @pitt-pmi.bsky.social ‬grad student @catmphelps.bsky.social synthesizes how exercise reshapes the immune system & the potential of exercise-based therapies for cancer, autoimmunity, and other diseases. www.cell.com/immunity/ful...

👀Ex-eye-ting research from Anthony St. Leger, associate professor of @pittophthalmology.bsky.social and @pitt-immunology.bsky.social! He and his team have developed a "living eye drop" that uses a genetically modified eye bacterium to boost healing. Read more: www.upmc.com/media/news/0...

Pitt Scientists Engineer “Living Eye Drop” to Support Corneal Healing

Pitt Scientists Engineer “Living Eye Drop” to Support Corneal Healing

upmc.com

Toward a consensus on the tumor microbiota: Evidence, standards, and interpretation: Cancer Cell www.cell.com/cancer-cell/...

Toward a consensus on the tumor microbiota: Evidence, standards, and interpretation

Tumors across diverse organs harbor microbial communities that can shape cancer biology and therapeutic responses, yet the field remains polarized by technical and interpretive challenges. In this com...

cell.com

Learn more about Dr. Gottschalk bit.ly/4bj0TOU, Dr. Hinterleitner bit.ly/3OCSr4o, and Dr. Meisel bit.ly/4aWO9MA (2/2)

Good things come in threes! Please join us in congratulating @gottschalklab.bsky.social, @rh-lab.bsky.social, and @meisellab.bsky.social on promotion to associate professor! (1/2)

What is gut health? A new consensus statement in @natrevgastrohep.nature.com , co-authored by @meisellab.bsky.social, finally defines it—and outlines a framework for research and clinical practice. Read it here: www.nature.com/articles/s41...

We're excited to host a distinguished lineup of speakers at @CellSymposia #CSHallmarks2026, including keynote speakers @johannajoyce.bsky.social & Faisal Mahmood @harvardmed.bsky.social. View the full speaker lineup: http://dlvr.it/TPbBpQ

Physical activity and the reduction of all-cause mortality, from 2 very large prospective cohorts 1. The relationship is non-linear, suggesting a threshold effect for many types of exercise as seen below

We're excited to host a distinguished lineup of speakers at @CellSymposia #CSHallmarks2026, including keynote speakers @johannajoyce.bsky.social & Faisal Mahmood @harvardmed.bsky.social. View the full speaker lineup: http://dlvr.it/TPbBpk

Preview @cp-immunity.bsky.social Cutting the Gordian knot: Untangling gasdermin C from pyroptosis www.cell.com/immunity/ful... on www.cell.com/immunity/ful...

Thanks for highlighting our work!

Eric Topol@erictopol.bsky.social · 10mo ago

How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite www.cell.com/cell/abstrac...

Congrats, @catmphelps.bsky.social !

Pitt Program in Microbiology & Immunology@pitt-pmi.bsky.social · 11mo ago

Congratulations to PMI student @catmphelps.bsky.social who is the recipient of the 23rd Stephen L. Phillips Scientific Achievement award for a Pitt School of Medicine graduate student who authored the best peer-review scientific journal author this year!

Congratulations to PMI student @catmphelps.bsky.social who is the recipient of the 23rd Stephen L. Phillips Scientific Achievement award for a Pitt School of Medicine graduate student who authored the best peer-review scientific journal author this year!

🔬 OBS Seminar Shaping CD8+ T Cell Response Through Microbiota Metabolites 🗣️ Joseph Stevens @cincyresearch.bsky.social @cincykidsallergyim.bsky.social 🗣️@catmphelps.bsky.social @meisellab.bsky.social 🗓️ Thu, September 4th, 11 AM EDT, 3 pm GMT, 5 pm CET 👇 us02web.zoom.us/meeting/regi...

#ResearchHighlight In a study published in #Cell, Phelps et al. find a mechanism connecting exercise, gut microbiota & anti-tumour immunity; exercise induces microbiota to produce formate, which in turn enhances CD8+ T cell functionality. 👇

No strain, no formate gains - Nature Reviews Cancer

In a study published in Cell, Phelps et al. find a mechanism connecting exercise, gut microbiota and anti-tumour immunity; exercise induces microbiota to produce formate, which in turn enhances CD8+ T cell functionality.

nature.com

Congratulations to the team! Excited to see the study in print!!

Reinhard Hinterleitner@rh-lab.bsky.social · last yr.

Excited to share our new publication in collaboration with Yi-Nan Gong: Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity: Immunity www.cell.com/immunity/ful...

Excited to share our new publication in collaboration with Yi-Nan Gong: Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity: Immunity www.cell.com/immunity/ful...

Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

Pandey et al. identify Cathepsin S (CTSS) as the direct protease that cleaves Gasdermin C (GsdmC) in the intestine. Type 2 immune-promoting microbes trigger CTSS-dependent GsdmC activation in intestin...

cell.com

AAI Members in the News! For her grad thesis with Dr. Marlies Meisel at ‪@pittdeptofmed.bsky.social‬, ‪@catmphelps.bsky.social‬ showed how #exercise improves #cancer outcomes and enhances the response to #immunotherapy in mice by reshaping the gut #microbiome 🔗 www.medschool.pitt.edu/news/gut-mic...

Thanks @nature.com for highlighting our recent study #exercise #microbiota #cancer

Nature@nature.com · last yr.

Exercise helps the immune system to fight tumours by stimulating microbes in the gut to make a compound known as formate go.nature.com/4lIZx2m

Exercise seems to help prevent cancer and reduce the growth of tumours, but until now, we didn’t know why. The key seems to lie in the gut’s microbiome.

Exercise helps fight cancer – and we may finally know why

Exercise seems to help prevent cancer and reduce the growth of tumours, and that protective effect may be due to the way working out changes the gut microbiome

newscientist.com

Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression @cellcellpress.bsky.social @catmphelps.bsky.social @meisellab.bsky.social www.cell.com/cell/fulltex...

📄🧫🔬🐭What are you reading this weekend? Check out @catmphelps.bsky.social, @meisellab.bsky.social, et al’s brand new work! #H2P

meisellab.bsky.social@meisellab.bsky.social · last yr.

Our lab just completed a +6 year #marathon, describing for the first time that the #microbiome is critical for #exercise - induced increases in antitumor CD8 T cell immunity and improved of #cancer #immunotherapy. www.cell.com/cell/fulltex...

www.upmc.com/media/news/0...

Gut Microbes Key to Understanding How Exercise Boosts Cancer Immunity

Gut Microbes Key to Understanding How Exercise Boosts Cancer Immunity

upmc.com

Now online! Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression.

dlvr.it

I am BEYOND excited to share that my PhD thesis research is officially published in @cellpress.bsky.social today. Read on for an exciting story about how #exercise promotes antitumor #immunity by modulating behavior of the #microbiome 🏃‍♀️🦠 authors.elsevier.com/c/1lPCrL7PXu...

How exercise works through the gut microbiome to enhance response to cancer immunotherapy www.cell.com/cell/fulltex... @cellpress.bsky.social