⏯️Webinar replay: Everything you wanted to know about pre-mRNA splicing but were afraid to ask 🎤 Speaker: Aaron Hoskins, @uwmadisonrna.bsky.social Watch for an overview of pre-mRNA splicing and the cellular machine responsible — the spliceosome: www.youtube.com/watch?v=Hf2w.... #RNAResearch

Everything you wanted to know about pre-mRNA splicing but were afraid to ask

YouTube video by American Society for Biochemistry and Molecular Biology (ASBMB)

youtube.com

ICYMI: New Online! Exchange dynamics and kinetic control of gene regulation complexes

Exchange dynamics and kinetic control of gene regulation complexes

Nature Reviews Molecular Cell Biology, Published online: 30 July 2026; doi:10.1038/s41580-026-00991-zRecent evidence reveals how gene expression complexes form transient assemblies that continually exchange their subunits under kinetic control. This Perspective proposes that these dynamics form the basis of RNA processing and gene regulation.

dlvr.it

For 40 years the 8-nt ‘Kozak Sequence’ was thought to mark sites of translation initiation. In a new study, we revise this model by identifying an ~80-nt sequence—the extended Translation Initiation Sequence (eTIS)— that guides ribosomes to correct start sites. 🧵 www.biorxiv.org/content/10.6...

Come join us in Würzburg!

Sharma Lab@sharmalab.bsky.social · 4w ago

Exciting opportunity: We are recruiting 3 Independent Group Leaders for our Munich-Würzburg Cluster of Excellence #NUCLEATE on Nucleic Acid Sciences and Technologies 🧬. www.nature.com/naturecareers/job/12861192/independent-group-leader-at-nucleate-excellence-cluster/ @nucleate-cluster.bsky.social

Exciting opportunity: We are recruiting 3 Independent Group Leaders for our Munich-Würzburg Cluster of Excellence #NUCLEATE on Nucleic Acid Sciences and Technologies 🧬. www.nature.com/naturecareers/job/12861192/independent-group-leader-at-nucleate-excellence-cluster/ @nucleate-cluster.bsky.social

Independent Group Leader at NUCLEATE Excellence Cluster - Munich or Würzburg job with NUCLEATE Cluster | 12861192

Independent Group Leader in Nucleic Acid Sciences and Technologies within the NUCLEATE Cluster at LMU Munich, TU Munich or JMU Würzburg.

nature.com

How can a splicing factor bind to thousands of exons but regulate only a few of them? In our new preprint, we show that SRSF6 resolves this paradox through two distinct binding modes. @lab-nmr.bsky.social & @julianvonehr.bsky.social. Check it out: www.researchsquare.com/article/rs-9...

One week left to apply. Help us find new antimicrobials and understand the inner workings of bacteria – as a technical assistant in the Machine Biophotonics and Nanoscale Bacteriology labs at the Rudolf-Virchow-Zentrum, University of Würzburg – See details below (in German). Please spread the word.

It‘s not always the best solution to do your CRISPR(i) screen at a low MOI (or the dogmatic 0.3-0.5 range 😉) - superinfection can give you a higher quality output! Super cool to finally see some of @chnebster.bsky.social postdoc work out and published!

Stefan Oberlin@chnebster.bsky.social · 2mo ago

A project from my postdoc in the McManus lab @mcmanuslab.bsky.social at UCSF @ucsfdc.bsky.social is out today 🎉 For years, pooled CRISPR screens have operated under a central assumption: one perturbation per cell. We challenged that assumption. 🤯 www.nature.com/articles/s41592-026-03095-w

What should Europe do when demand for #ERC funding keeps rising? Restrict access or invest in excellence? Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness Consider to share & sign - see below 🧪

#erc | Johanna Joyce

What should Europe do when demand for its most successful frontier research programme keeps rising? Restrict access, or invest in the excellence it has created? A new open letter, spearheaded by Sara...

linkedin.com

Our genes come in bits & pieces!🧬Learn how splicing "cuts & pastes" RNA to create different proteins from a single gene, for its discovery the 1993 Nobel Prize in Physiology or Medicine was awarded. www.youtube.com/watch?v=-x7H... @snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social

RNA Explained: Split Genes – RNA Splicing & Protein Diversity

YouTube video by NCCR RNA & Disease

youtube.com

19F NMR is such a powerful tool! Lovely NMR work ❤️

Woodson Lab@woodsonlab.bsky.social · 4mo ago

Our new paper is out! Using 19F NMR, we show that Hfq rewires the conformational dynamics of a model sRNA in a site-specific manner. Uridines at the rim undergo faster exchange (~100 μs) than those in the proximal pore (~300 μs). Congrats Elise! 🎉🎉 www.sciencedirect.com/science/arti...

Yale MB&B's Karla Neugebauer and Guillermina Kubaczka have been featured in a new @natmethods.nature.com piece 🌍🔬 The article spotlights researchers bridging the molecular and planetary scales to address global health challenges. @karlaneugebauer.bsky.social www.nature.com/articles/s41...

Cell biology’s fantastic voyage to Planet Earth - Nature Methods

A nascent group of researchers sees planetary health as an urgent reason to bridge the molecular and planetary scales. This is shaping their strategies, methods, collaborations and outlook about their...

nature.com

looking forward to reading this! Love to see an RRM-by-RRM dissection as similar principles are employed by so many multi-RBD proteins.

Zarnack Group@zarnack-group.bsky.social · 4mo ago

NAR breakthrough alert 🎉 Joint work with @mfeldbruegge.bsky.social on Rrm4. We dissect its modular RRM binding code & how domain combinations shape RNA interactions. Like finding needles in a haystack, comparative iCLIP sorts functional vs accessory sites. Work by Nina & @srimeenakshi.bsky.social

❗️5 days left to apply for a PhD position in our group👇

Lea H. Gregersen@gregersenlab.bsky.social · 5mo ago

Passionate about transcription? 🚀 We’re recruiting a PhD student in Transcriptional Regulation at @ucph.bsky.social Start Summer 2026 Work with RNA, CRISPR, sequencing & proteomics in the Gregersen Lab @cgen2025.bsky.social Meet us: gregersenlab.com Apply by Apr 10, 2026👇 tinyurl.com/PhD-CGEN

Very neat and cool!

Aaron and the Hoskins Lab at UW Madison@uwmadisonrna.bsky.social · 4mo ago

Lots of papers out today! From Doug Black and Hong Zhou's labs: structural mechanism of RBM5 regulated splicing via U2 interactions The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing Shiheng Liu et al.. www.biorxiv.org/content/10.6...

Lots of papers out today! From Doug Black and Hong Zhou's labs: structural mechanism of RBM5 regulated splicing via U2 interactions The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing Shiheng Liu et al.. www.biorxiv.org/content/10.6...

Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...

Cryo-EM structure of yeast telomerase

YouTube video by MRC Laboratory of Molecular Biology

youtube.com

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 4mo ago

Led by Investigator Scientist @hongmiaohu.bsky.social, @kellythd-nguyen.bsky.social’s group in the LMB’s Structural Studies Division have produced the first ever structure of telomerase from yeast. Read more here: mrclmb.ac.uk/news-events/... #LMBResearch #cryoEM 🧪

Happy to share our latest work on the previously uncharacterized splicing factor Cwc15! Importantly, all of the people who did this work are/were undergrads! S. cerevisiae Cwc15p Tunes the Spliceosome Active Site for 5' Splice Site Cleavage www.biorxiv.org/content/10.6...

Excited to share the first preprint from the lab! We show that ApeA defends against RNA phage infection by cleaving the phage genome: www.biorxiv.org/content/10.6...

🌱 🚨Postdoc position – Plant Chromatin Biology (Strasbourg) Grob and Jullien Lab - details attached 📅 Apply by March 30, 2026 📩 stefan.grob@cnrs.fr Please share with anyone who might be interested! #Postdoc #PlantScience #Epigenetics #Chromatin

Postdoc positions available in my lab in Aarhus, Denmark on 'Mammalian Nuclear RNA Production and Turnover Systems'. Please get in touch for further information or simply apply here: mbg.au.dk/en/news-and-...

Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University

Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

mbg.au.dk

You are finishing your PhD and looking to continue in science? The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro.... Thanks for reposting!

We are excited to share our new preprint: iCLIP3 — an improved protocol for transcriptome-wide mapping of protein–RNA interactions at single-nucleotide resolution.

bioRxivpreprint@biorxivpreprint.bsky.social · 5mo ago

iCLIP3: A streamlined, non-radioactive protocol for mapping protein-RNA interactions in cellular transcripts at single-nucleotide resolution https://www.biorxiv.org/content/10.64898/2026.03.01.708747v1

Exciting news: Our RNA community in @uniregensburg.bsky.social is set to grow! We are opening a Junior Group Leader position in RNA biochemistry / ribonucleases / RNA stability. A great opportunity to start your own team within our collaborative RNA network. Details & application 👇

We have an open position for a #PhD student (last week to apply!) & a lab technician/TA. For more information see: www.beuschlab.org/join-us Interested in understanding post-transcriptional regulation and how #RNA #splicing decisions are made? Then take a look or share with people who might be! 🧪🧫

RNA Splicing Lab - JOIN US

Are you interested in investigating basic mechanisms in splicing regulation and gene expression? Our research group was launched in September 2024 and is hosted at the Institute of Molecular Infection...

beuschlab.org

Our Lab is searching a postdoc for an exciting ERC-funded project that will start this summer. Apply if you’re passionate about multi-omics, cutting-edge computational approaches, and exploring biological questions across the animal 🪼 🪱 🐞 🦎 🦋 🕷️ tree of life www.biozentrum.unibas.ch/open-positio...

I have a PhD student and a post-doc position available in my lab to work on plant photobiology. Please use the links below to postulate. Please RT, many thanks career5.successfactors.eu/career?caree... career5.successfactors.eu/career?caree...

I am currently recruiting PhD students, both computational and experimental jobs.helmholtz-muenchen.de/qb2hm and jobs.helmholtz-muenchen.de/ut89o Feel free to contact directly or share with anyone interested.

PhD Position in Machine Learning for Single-Cell Genomics (f/m/x)

jobs.helmholtz-muenchen.de

Thrilled to announce that I’ve just opened my research lab at @helmholtz-hiri.bsky.social ! A huge thank you to my mentor Roi Avraham (and lab members!) for the incredible training and support that made this possible.

Do you want to understand how RNA #splicing decisions are made? We‘ve got a PhD position open for you (see 👇👇)!! Please share #RNAsky and RT! tinyurl.com/4ztu9cb9