🧬 We’ve shared an open-access protocol for cost-effective, high-quality DNA extraction from cyanobacteria and microalgae. We hope it will be useful to the research community! Developed with @Raul_MontanezM. doi.org/10.17504/pro... #Cyanobacteria #Microalgae #DNAExtraction #Genomics #ProtocolsIO

Lab protocol: DNA extraction from cyanobacteria and microalgae

Lab protocol: DNA extraction from cyanobacteria and microalgae. Photosynthetic microorganisms are key. Read full protocol, steps, and materials on protocols.io

doi.org

Access the full protocol on protocols.io: www.protocols.io/view/rsv-a-a...

Bring structure to your research - protocols.io

A secure platform to develop, share, and discover reproducible research methods, protocols, and workflows across teams and the global scientific community.

protocols.io

"RSV-A and RSV-B Amplicon Sequencing from Solid-Phase Wastewater Using the NEBNext® RSV Primer Module" is a novel protocol by CIDMATH researchers Said Rachida, Alaa Ahmed, Hannah Cayla D., Abby Paulos, Orlando Sablon, Marlene Wolfe, and Anne Piantadosi.

Open science has been central to this project from the beginning. We've made our laboratory and sequencing protocols openly available so that others can build on the framework. 🧫 Laboratory protocols www.protocols.io/view/getcamp... 🧬 Sequencing protocols www.protocols.io/view/getcamp...

🧵 New paper! 🚨 Delighted to see our GETCampy-Africa protocol published in BMJ Open. *Protocols for genomic epidemiology and source attribution of enteric bacteria causing diarrhoeal disease across Africa* @bmj.com @bmjmedicine.bsky.social 📄 bmjopen.bmj.com/content/16/6... 👇

A protocol for performing whole genome sequencing of individual Schistosoma haematobium larva stored on FTA cards. Following this protocol (inc. diagnosis), with list price consumables, I currently estimate one can achieve a ~50x coverage of each genome for ~£104 www.protocols.io/view/schisto...

Schistosoma haematobium larva FTA-to-WGS

Schistosoma haematobium larva FTA-to-WGS. This protocol describes the isolation of individual schistos. Read full protocol, steps, and materials on protocols.io

protocols.io

As we near the end of #EarthWeek, a reminder that #zebrafish do not need sterile dishes! Save money and reduce plastic consumption by sanitizing used dishes with hot water or dilute bleach 🧫💦 For example, you could follow this protocol from the Fish Floor at UCL: www.protocols.io/view/washing... 🐟 🧪

www.protocols.io/view/cryo-ex... New protocol alert!! Cryo-expansion microscopy of C. elegans and Tardigrades using the high pressure freezer!

Cryo-Expansion Microscopy of C. elegans and Tardigrades

Cryo-Expansion Microscopy of C. elegans and Tardigrades. Expansion microscopy (ExM) improves imaging r. Read full protocol, steps, and materials on protocols.io

protocols.io

delighted to share our new pre-print developing label-free glycosaminoglycan analysis of diverse complex biological samples, led by @h-davies-s.bsky.social working closely with David Knight and Rebecca Miller alongisde our recent recruit Samie Dalgarno www.biorxiv.org/content/10.6...

Modern research is increasingly collaborative, creating a need for clearer, shared workflows. Join us on May 5, 2026 at 14:00 CET | 13:00 GMT for a webinar on how research teams are adapting and collaborating at scale. Register here: go.springernature.com/int1/pf040/e...

We’re transforming research protocols from static documents into dynamic, reusable workflows. A key part is making large collections of trusted methods — including Protocol Exchange and Springer Protocols — available in protocols.io format, so researchers can reuse, adapt, and build on them.

Evolving protocols: From static to dynamic with protocols.io

Sharing research protocols is a cornerstone of open science, and protocols.io, part of Springer Nature, continues to evolve as a secure, modern platform for...

protocols.io

Strengthening transparency and reproducibility starts with sharing research work openly. Our latest blogs offer guidance for: > How to share research code openly: spklr.io/63329Eynzz > How to share research protocols and methods openly: spklr.io/63322EynzO

Attending ABRF 2026 (@abrf.bsky.social)? Connect with protocols.io at Booth 710. We're engaging with core facilities about common priorities and challenges, including how to demonstrate impact and receive credit. If this resonates, schedule a short discussion with our team: abrf26.youcanbook.me

Excited to share my PhD work! The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development. Here’s a quick Blue-torial 🙂 (1/n) www.nature.com/articles/s41...

Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila - Nature Genetics

Pico-C, a low-input Micro-C approach, reveals that dynamic three-dimensional genome folding precedes zygotic genome activation in Drosophila.

nature.com

Join our webinar to hear from researchers at the University of Rochester and City of Hope on practical strategies for improving documentation, supporting training, and increasing visibility of core facility work. April 9 | 11 AM EST | 5 PM CET Register here: go.springernature.com/enhancing-im...

Last month, we highlighted Protocols.io as a new resource available at @bodleian.ox.ac.uk. Next week, as part OxFOS, you can sign up and join the Springer Nature team for a training session introducing the platform to researchers either in person here at the RSL or online go.glam.ox.ac.uk/proto

Started this project years ago, but now everything is deposited on @addgene.bsky.social and a short @protocolsio.bsky.social is online. Try it out to make your own (cheap) homemade nuclease/Benzonase! dx.doi.org/10.17504/protocols.io.261ged7xov47/v2 Thank you @jcoker10.bsky.social and Michael Lim!

We've updated our protocols.io page to highlight a couple of the protocols published by Crick authors recently. If you're at the Crick, don't forget you can get your flat pdfs converted to the protocols.io format at no cost! 😀 www.protocols.io/organization...

A Lab Protocol by Omid Gholamalamdari and Stephanie C. Weber details an optimized method for labeling of nascent RNA transcripts in the C. elegans intestine, enabling spatial analysis of transcription dynamics. plos.io/3Ox4rnO @protocolsio.bsky.social link: plos.io/3O9Jv6g

Labeling of nascent RNA in the C. elegans intestine

Transcriptional regulation in C. elegans has been difficult to study at the level of nascent RNA because nucleotide analogs do not readily penetrate the cuticle. Here, we establish an ex vivo…

plos.io

New @protocolsio.bsky.social post describing our new protocol for generating intestinal organoids for #stickleback: www.protocols.io/view/generat... With work by postdoc Arshad Padhiar, funded by @moorefound.bsky.social

Generation of Stickleback intestinal organoid

Intestinal organoids offer significant advantages over conventional 2D cultures, providing a physiologically relevant 3D architecture that enables more realistic disease modelin...

protocols.io

Given the recent #Nipah outbreak in India, here are two #Nanopore protocols for NiV genomic sequencing in support of rapid outbreak response: IPC: www.protocols.io/view/sequenc... icddr,b/CDC: journals.asm.org/doi/10.1128/...

💡 Did you know? Methods are among the most cited research outputs. For #LoveMethods26, join experts for interactive sessions: 👉 Jan 21: @protocolsio.bsky.social Hackathon 👉 Jan 22: Methods Mythbusting Panel spklr.io/633288eAVM #OpenScience

Happy International Love Methods week! The Crick partners with @protocolsio.bsky.social to share open methods, and if you happen to be a Crick researcher, you can use their protocol writing up service for free (while codes last!) www.protocols.io/we-enter-pro...

We will import and format your protocol

Paper protocols floating on your benchtops? We can digitize them for you!

protocols.io

Join Springer Nature editors and the protocols.io team for two exciting events as part of #LoveMethods26! 💻Transform your protocols at our Hackathon on Jan 21 🔮Gain insight on methods publishing at our Methods Mythbusting on Jan 22 👉FREE registration & more details:

Join protocols.io and Springer Nature editors at Love Methods Week 2026

Love Methods Week 2026 will take place January 19-23, 2026 and is organized by University of Coimbra and the QUEST center. Online workshops focused on open and reproducible meth...

protocols.io

Join Springer Nature editors and the protocols.io team for two exciting events as part of #LoveMethods26! 💻Transform your protocols at our Hackathon on Jan 21 🔮Gain insight on methods publishing at our Methods Mythbusting on Jan 22 👉FREE registration & more details:

Join protocols.io and Springer Nature editors at Love Methods Week 2026

Love Methods Week 2026 will take place January 19-23, 2026 and is organized by University of Coimbra and the QUEST center. Online workshops focused on open and reproducible meth...

protocols.io

Our promoted new resource for January is Protocols.io. Using Protocols.io researchers can create and share detailed experimental protocols with colleagues or the wider scientific community www.protocols.io

Join us for “Methods Mythbusting: Insights from Journal Editors and protocols.io”protocols.io/webinars/met...rs at Love Methods Week 2026excelscior.uc.pt/love-methods...6/ #LoveMethods26

🎉 We are thrilled to announce that our protocol “Library construction for ONT long read cDNA”, developed at our GenomiqueENS core facility, is available on protocol.io. dx.doi.org/10.17504/protocols.io.4r3l21oepg1y/v1

🧬Searching for a Nanopore RNA-seq protocol that generates longer reads than the manufacturer’s protocol, and applicable for low-input material ? 🤔

Really liking the idea and output of GAQETv2 - such a cool tool for structural genome annotation QC!! www.protocols.io/view/structu...