RNAHelix

@rnahelix.bsky.social

physician-scientist Assistant Professor @ucsf. #newPI stemcellbio+RNA/omics scientist | liver pathologist | founder @MDPhDEquity.bsky.social | BWF CAMS | ASCI YPSA | alum @ucsf @DukeMSTP @Stanford | http://csangokoya-mdphd.com | sangokoyalab[dot]ucsf.edu

The ISSCR offers Child & Dependent Care Grants for members attending ISSCR 2026 to help cover additional care costs while at the meeting. Grants are reviewed on a first-come, first-served basis. Apply before 4 March 2026 👉 https://bit.ly/4qZ0Spq

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David Baltimore passed away this weekend. A pioneer of molecular virology who won the Nobel prize in medicine & physiology for his discovery of viral reverse transcriptase. This essay he wrote in 2018 reflecting of his 60yr career in science is a great read. www.annualreviews.org/content/jour...

Sixty Years of Discovery | Annual Reviews

Each of us is a story. Mine is a story of doing science for 60 years, and I am honored to be asked to tell it. Even though this autobiography was written for the Annual Review of Immunology, I have ch...

annualreviews.org

I care for children in the hospital on inpatient & consult services. Most weeks there are at least a few kids admitted with vaccine preventable diseases. Often in children who can’t get vaccinated themselves. 15 years in pediatrics and I’ve never seen a single one admitted with vaccine injury.

nice to be spotlighted by @isscr.org this month! The ISSCR is a great community for scientists, clinicians, patients, and the public -- check out www.isscr.org to learn more about stem cell initiatives +learning, public syllabi and the new Stem Cell Medicine CME course. www.isscr.org/isscr-news/m...

International Society for Stem Cell Research

The ISSCR is the largest, most respected society of stem cell researchers in the world. The non-profit organization represents 5,000 scientists, educators, ethicists, and business leaders across 80 c...

isscr.org

one small consolation of being a 60+ year old investigator is the ability to submit to 𝘔𝘈𝘛𝘜𝘙𝘌 family journals — sure they’re low impact (for our knees) but they have an early bird special if you submit between 4:00 and 5:30 on weekdays

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We are deeply saddened by the passing of Dr. Atul Butte, a visionary scientist, educator and leader whose work reshaped biomedical research and health care. We extend our heartfelt condolences to Dr. Butte’s family, colleagues, trainees and collaborators. ucsfh.org/4n25xVH

Dr. Atul Butte smiles at the camera in a grey suit.

There are few things as cost effective as Narcan, especially in a country where (entirely preventable) opioid overdoses have been a leading cause of death for years. For every 6 kits distributed 1 OD is prevented. The $56M in this grant trained >66K people and distributed >282,500 kits in 2024 alone

RFK Jr. to End 'Godsend' Narcan Program That Helped Reduce Overdose Deaths Despite His Past Heroin Addiction

Despite overcoming heroin addiction himself, RFK Jr. is backing plans to cut a critical Narcan program that helped reduce overdose deaths.

latintimes.com

I received a surprising and disturbing request from NIH on Friday. They wrote to cancel a subaward to Hong Kong on one of my grants. (This was disturbing but not surprising.) They also ordered us not to interact with our collaborators in Hong Kong on any work under the award:

Screenshot of email stating "The subaward and the associated amounts listed above will need to be removed from the current and future year awards, and any other amounts budgeted for activities related to the Hong Kong research must also be removed. No rebudgeting of these funds is permitted, and no involvement or collaboration with researchers in Hong Kong or China is permitted in connection with the activities of this award, regardless of whether any funds are transferred," with the "no involvement" clause highlighted.

congratulations Christina Homer on your publication! another one from this outstanding @hhmi.org Hanna Gray Fellow and physician-scientist at UCSF!! @christinahomer.bsky.social

PLOS Biology@plosbiology.org · last yr.

Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @plosbiology.org 🧪 plos.io/4cINMpl

Top: Micrographs of fixed samples from each flask at the time of RNA harvest. Endospore release was first observed on day 3. Bottom: Schematic of Regulation of gene expression in Coccidioides development. The data uncover regulatory modules in Coccidioides development. The majority of Coccidioides transcription factors (TFs), depicted as triangles in the figure, show enhanced expression in spherules compared to hyphae. These TFs, along with RYP1 (green hexagon) and a second regulator whose motif is reported here, guide the expression of endospore-associated transcripts and secreted effectors, including proteases. RYP1 also controls a core regulon, that is, expressed in both spherules and hyphae via a canonical RYP1 motif. Finally, in arthroconidia, RYP1 impacts the transcriptome, but likely through indirect regulation of one or more additional key regulators.

For the last 3 yrs, I was the director for the Science of Science program at the NSF. We funded projects on science communication - science communication to the public, communication of public priorities to scientists, citizens engagement & participation in science. 🧵

The NYT wants you to think universities became dependent on government. This is false. The government invested in the national research infrastructure by competitive grants to universities. The taxpayers built this. It got us to the moon. Won the Cold War. Created Silicon Valley. Made the McRib.

The post- World War II US investment in R&D is one of the greatest economic and national security engines in history. As I said to @revkin.bsky.social a decade ago, “the budget is policy”. We should expand R&D, not shrink it. Broaden participation not restrict it. archive.nytimes.com/dotearth.blo...

Panel's Latest Warming Warning Misses Global Slumber Party on Energy Research

The latest global warming report from the U.N. climate panel helpfully clarifies risks but largely misses a key factor in driving an energy transformation — research.

archive.nytimes.com

This reminded me of an experience I had when I was EiC at Science. Through a friend, I was introduced to members of the CO2 Coalition. This is a group that promotes the idea that CO2 is good for plants and, therefore, good for the planet and that demonization of CO2 was inappropriate. 1/n

Jeremy Berg@jeremymberg.bsky.social · last yr.

ATTENTION Today's moment of WTF (Sorry, one of today's moments of WTF...) The EiC of CHEST received a letter from the Acting US Attorney in DC asking about misinformation, etc. DOES ANYONE KNOW IF OTHER EiCs HAVE RECEIVED SIMILAR LETTERS? DM me or on Signal jeremymberg.78 THANK YOU