Front-of-package food labeling highlighting sodium, saturated fat & added sugars can serve as an effective catalyst for empowering consumers to make healthier food choices & improving ❤️ health. Learn more in the 🆕 ACC Concise Clinical Guidance ➡️ bit.ly/3McUHOJ #JACC #CardioSky #MedSky #cvPrev
Romit Bhattacharya
@romitb.bsky.social
Preventive Cardiologist at Mass General Hospital | Lifestyle, Genomics, Digital Health, South Asian CVD
Was happy to join @boston25news.com 🎥for a discussion of alcohol and heart disease yesterday! Recent trends show Americans are drinking 🥃🍺 less - what does this mean for the heart? 🫀 www.boston25news.com/news/local/d... @massgeneralbrigham.bsky.social
Dr. Romit Bhattacharya: Survey shows fewer adults drinking alcohol for health reasons
A new Gallup survey reveals that more Americans are choosing to abstain from alcohol.
boston25news.com
🆕 New in AJPC: High-Density Lipoproteins, Part 1 Explore HDL's role in CVD prevention—epidemiology, antiatherogenic effects & therapies to raise serum levels. 🔗 www.sciencedirect.com/science/arti... #HDL #Cardiology #LipidHealth #AJPC #PreventiveCardiology
An abs risk generalizable risk calculator is challenging. Led by @somijemmacho.bsky.social, evaluating AHA PREVENT across 4 academic health systems, we found similar discrimination but variable calibration. A universal abs risk threshold may not suitably guide www.sciencedirect.com/science/arti...
Thrilled that our work on integrating genetic, contemporary and traditional risk factors into acute MI models has been published in @CirculationGenomeandPrecisionMedicine @ahascience.bsky.social !! Are genetic and contemporary risk factors as powerful as traditional RFs? #CardioSky #cvPrev
Our study led by @romitb.bsky.social & C. Marnell shows that, when simultaneously considering clinical, laboratory, and genetic risk factors for incident CAD prediction, the top 2 model explanatory factors are: 1. Hypertension 2. CAD polygenic risk score www.ahajournals.org/doi/10.1161/...
Huge thank you to Dr. Steve Grinspoon for inviting me to moderate the Harvard Nutrition Obesity Research Symposium at MGH! Watch this space for insights and work from our faculty! #CardioSky #EndoSky @mghcvrc.bsky.social @jsawallagusehmd.bsky.social @drprao.bsky.social @pnatarajanmd.bsky.social
Flavonoid food and beverage intake—quantity and diversity— is linked to reduced all-cause mortality, cancer, cardiovascular disease, Type 2 diabetes, and neurodegenerative disease www.nature.com/articles/s43...
Steffensen, Rasmussen, et al. show that deep whole-exome sequencing of human atherosclerotic plaques reveals that the expansion of large mutated clones within plaque tissue is an intrinsic feature of human atherosclerosis: buff.ly/zdEM0dm
Peer Review In Peril @aniloza.bsky.social "But now, “the Trump administration feels very strongly that the president’s agenda is the most important consideration for any government spending" www.statnews.com/2025/05/27/r... #Cardiosky
‘Corrupt’ medical journals have to change, RFK Jr. says, or the NIH will publish in-house
The criticism of The Lancet, NEJM and JAMA is not new, but the health secretary may use his position to influence research that journals publish.
statnews.com
📢 Just published! New insights on Lipoprotein(a): How it interacts with common cardiovascular risk factors to influence CVD risk — findings from the UK Biobank. www.sciencedirect.com/science/arti... #LipoproteinA #CVDprevention #CardioSky #PreventiveCardiology #ASPC #HeartHealth #UKBiobank
Our study led by A. Flores & with @aniruddhpatelmd.bsky.social describes a new peripheral artery disease PRS. Predictive capability for incident PAD is comparable to CKD & DM2. Among those with PAD, it also associates with major adv limb events jamanetwork.com/journals/jam... @jama.com #JAMACardio
Wow!!! These human genetic insights could enable the next generation of pain management therapies: rupress.org/jem/article/... Fascinating @jem.org article!
A pathological missense mutation in the deubiquitinase USP5 leads to insensitivity to pain | Journal of Experimental Medicine | Rockefeller University Press
The manuscript reports on patient with a USP5 mutation that gives rise to insensitivity to pain. The patient’s pathology is phenocopied in a knock-in mouse
rupress.org
In stable patients with extensive noncalcified plaque volume at baseline, 18 months of evolocumab treatment was associated with a shift toward a lower risk quantitative plaque phenotype and reduction in microcalcification activity www.jacc.org/doi/10.1016/...
Effects of Evolocumab on Coronary Plaque Composition and Microcalcification Activity by Coronary PET and CT Angiography:
jacc.org
Here's the thing... pseudoscience can't do this. Only real science can. www.nytimes.com/2025/05/15/h...
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
nytimes.com
Very excited to Chair this webinar on Cardiovascular Health May 21 7:30-8:30p ET hosted by @indiaspora.bsky.social with Opening Remarks from Vivek Murthy. Register us02web.zoom.us/meeting/regi... @drmarthagulati.bsky.social @mgbresearch.bsky.social @broadinstitute.org @harvardmed.bsky.social .
Lp(a) & recurrent atherosclerotic CV events: US Family Heart Database #CardioSky academic.oup.com/eurheartj/ad... @hsbhatia.bsky.social @psatishmd.bsky.social @vietheartpa.bsky.social @anastasiasmihaili.bsky.social @michaeldshapiro.bsky.social @romitb.bsky.social @dlbhattmd.bsky.social
Among N=2530 w HeFH or ASCVD on max tolerated LLT with insufficiently low LDL-C (mean 98mg/dl), obicetrapib (CETPi) 10mg po daily v placebo led to 33% lower LDL-C at 3mo www.nejm.org/doi/full/10.... @nejm.org #EAS2025
The most math equations written on a whiteboard by a clinician I've seen - yet amazingly well delivered to a broad audience! S. Urbut's talk @broadinstitute.org A Practical Primer on Bayesian Statistics youtube.com/watch?v=jcFS... @mgbresearch.bsky.social @harvardmed.bsky.social
MPG Primer: A Practical Primer on Bayesian Statistics (2025)
YouTube video by Broad Institute
youtube.com
Now the discovery of the 4th gene variant which promotes short sleep (4-6 hours) with full restfulness, potentially a path to a drug for sleep efficiency someday www.pnas.org/doi/10.1073/...
The SIK3-N783Y mutation is associated with the human natural short sleep trait | PNAS
Sleep is an essential component of our daily life. A mutation in human salt induced kinase 3 (hSIK3), which is critical for regulating sleep durati...
pnas.org
Nice of @indiaspora.bsky.social to feature the OurHealth Study in their newsletter! #cvPrev #SouthAsianCVD #CardioSky
The OurHealth Study – Discovering the Causes Behind High Rates of Cardiovascular Disease and Diabetes in South Asians www.indiaspora.org/the-ourhealt... @indiaspora.bsky.social Please sign up and share! ourhealthstudy.org @romitb.bsky.social
Great study!
Our study led by A. Shankar shows that genotype-phenotype discordance of LDL-C (stronger polygenic predisposition to hypercholesterolemia for a given LDL-C) stratifies CAD risk - esp in normocholesterolemia. www.sciencedirect.com/science/arti... @jaccjournals.bsky.social #JACCADv
Thrilled to join Ankur Kalra and Jaideep Patel on the Parallax Podcast to discuss South Asian Cardiometabolic Disease We get into: - Knowledge gaps - Lifestyle and Genetics - Common difficulties for the cardiologist in guiding South Asian patients #SouthAsianCVD bit.ly/4jVIuti
Ep 133: South Asian Heart Health: Unveiling Risk Patterns and Prevention Strategies
Podcast Episode · Parallax by Ankur Kalra · 04/28/2025 · 55m
podcasts.apple.com
Our @aspcardio.bsky.social statement on South Asians & Cardiometabolic Health in @ajpcardio.bsky.social I had the honour of co-chairing this w/ the amazing Dr. Rohatji & @jaideeppatel.bsky.social 🙏🏽 to our entire talented team who brought this to life 📎 shorturl.at/4bJGz #CVPrev #Cardiosky
Honored to contribute to the @aspcardio.bsky.social Clinical Practice Statement on optimizing cardiometabolic health among South Asian individuals spearheaded by A. Rohatgi @drmarthagulati.bsky.social J. Patel www.sciencedirect.com/science/arti...
Very excited to share our preprint led by M. Levin @skoyama.bsky.social J. Woerner & with S. Damrauer assessing genome-wide pleiotropy of >1,000 clinical traits across ~1.7M individuals with nearly 30K locus-trait associations! www.medrxiv.org/content/10.1... @medrxivpreprint.bsky.social
“Studies of the past tell us that nitpicking the particular semantics of the term ‘concentration camp’ as they pertain to a place the government is actively sending people with no criminal history is highly associated with national stability,” said historian Kristen Boyd theonion.com/histori...
Historians: Quibbling Over Exact Definition Of Concentration Camp Sign Of Healthy Society
NEW HAVEN, CT—Calling such concern for linguistic precision a clear indicator of a thriving country, a panel of historians from Yale University issued a statement Thursday announcing that quibbling over the exact definition of a concentration camp was a sign of a healthy society. “Studies of the past tell us that nitpicking the particular semantics […]
theonion.com
@kevinh-phd.bsky.social Kevin Hall’s work has been so important and enlightening to nutrition science and preventive cardiology. I thought at least his work would be valued and supported with the stated priorities. This is truly saddening to hear.
After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.
In a new Science study, researchers report compelling evidence for a gut-joint axis involving bile acid metabolism and GLP-1 signaling in osteoarthritis development, advancing the understanding of osteoarthritis pathogenesis and opening new avenues for therapy. scim.ag/3Ec0bFM #SciencePerspective
Beyond wear and tear at the joint
Bile acid metabolism meets glucagon-like peptide 1 signaling in osteoarthritis
scim.ag