Hey, science community (whoever is here). Can you please help me amplify this message? Postdoc position available in Düsseldorf!

Really interesting results! Makes you wonder if this could link the role of mitochondria in ageing as well via mtDNA release and cGAS.

Eric Topol@erictopol.bsky.social · 10mo ago

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

Lovely news for the summer! My latest artwork was just published on the cover of @cp-cellmetabolism.bsky.social. Incredible science from @daveyboyhod.bsky.social lab! They discovered how pancreatic alpha cells regulate beta cell function via enriched GLP-1 receptor nanodomains.

Highland Wink of Arthur's Seat (BIMDG Meeting in Edinburgh) to the Finnish Seaside Juhannus! From whispering winds of the city below, to the shimmering shores of the Finnish midsummer night, where the sun refuses to set! ⛰️🔥😄 Happy Midsummer everyone!

This time science inspired collage workshop that @jonwolfmueller.bsky.social conceptualized for the students @unibirmingham.bsky.social

First time as a lecturer in Mitochondrial Summer School! It’s been a while since I got to enjoy the talks as a student. Had fantastic time meeting friends, making new ones and discussing everything mitochondria. Thank you @unioulu.bsky.social and FibroHealth for the lovely time at Rokua, Finland!

Muscle needs to make serine from glucose to protect the fibers from mitochondrial disease. Read our story, a tour de force of Anastasiia Marmyleva and Christopher Jackson @SWAN @STEMM Helsinki University www.cell.com/cell-reports...

De novo serine biosynthesis is protective in mitochondrial disease

Jackson et al. show that serine becomes an essential amino acid in mitochondrial muscle disease, delaying disease progression. Blocking local biosynthesis of serine challenges cellular phospholipid ho...

cell.com

I had the chance to host an art workshop for our postgraduate students at MSS @unibirmingham.bsky.social with @jonwolfmueller.bsky.social It was a great opportunity to combine science and art and enjoy some time together. 🎨 🧪 🧫 🧠 Thanks to everyone who joined — it was an inspiring and fun evening!

www.nature.com/articles/s42... Metabolites are not genes. repeat, please!

Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism

Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...

nature.com

Clinically translatable mitochondrial #GeneTherapy in muscle using tandem mtZFN architecture. By P. Nash, @mitogene.bsky.social & colleagues @mrc-mbu.bsky.social 🗞️ doi.org/10.1038/s443... Read also related N&V by A. Ghifari & M. Ott 👉 doi.org/10.1038/s443...

Huge congrats to Pavel Nash on publishing his PhD work! 🎉 We showcase a safer mtDNA gene therapy using a novel mtZFN architecture compatible with a single AAV. Thanks to the entire team! @mrc-mbu.bsky.social @mbu-postdocs.bsky.social #MitochondrialDisease #mtDNA www.embopress.org/doi/full/10....

Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture | EMBO Molecular Medicine

imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...

embopress.org

Application deadline approaching fast! If you are a PhD student or a postdoc register for this summer school in the happiest country in the world. Amazing program, amazing people, amazing place! ssl.eventilla.com/mitochondria...

Mitochondria Summer School

ssl.eventilla.com

What a lovely paper from @dplamartin.bsky.social and his team! Mechanistic insight to mtDNA turnover at the lysosomes. 📬

David Pla Martin@dplamartin.bsky.social · last yr.

Excited to share our latest paper in Science Advances! We finally dissected a new pathway for mitochondrial quality control upon mtDNA replication stress! Let’s start a short thread! 🧵 www.science.org/doi/10.1126/...

📌UK Funding Opportunities After Brexit: Experiences and Practical Guidance 🎙️Sofia Ahola, Vitória Baptista, Selin Tüzüner 🗓️13.3. 7:00 PM CET 🔗https://us06web.zoom.us/webinar/register/WN_6EmZmK8kSSaueDtQWhLz9A ➡ Network: network.febs.org/posts/febs-j... #YoungFEBS #onlinetalk #funding #career

🌍Euromit 2026 is coming to Angers!🌍 ✨The international congress dedicated to mitochondrial research, will take place in France, at the Centre des Congrès of Angers. from May 31 to June 4, 2026! ✨ 📢 Stay informed by following this page and get ready for an exceptional scientific experience! 🚀🔬

Today is #RareDiseaseDay Did you know there's still no cure for #mitochondrialdisease? @lilyfoundation.bsky.social are fighting to change this. We've invested over £3 million in research since 2007 Please help us to raise awareness of mito Find out more www.thelilyfoundation.org.uk

Ahead of #RareDiseaseDay, please join us to educate and increase awareness about rare mitochondrial diseases Getting mito in the public eye helps drive research, boost donations and improve clinical care for those affected Please share to advance rare www.thelilyfoundation.org.uk/affected-by-...

Nature, Science, Sauna, Mitochondria. Great line up of speakers! 😀 💚 Mitochondria Summer School in Finland May2025! 💚 www.oulu.fi/en/events/mi...

Mitochondria Summer School in Rokua

Join us for an immersive week at the Mitochondria Summer School 2025, where leading experts and researchers will explore cutting-edge topics in mitochondrial biology!

oulu.fi

Astonishing paper that makes you question if you truly understand #mitochondrial dynamics 😅 The complexity of Parkin, Oma1, Opa1, Mfn1 in coordinating mitochondrial fitness. The story of Megamitochondria with MegaDNA and an overwhelming amount of mouse crosses www.nature.com/articles/s41...

Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1 - Nature

We find that, in mice, although the individual loss of Parkin or OMA1 does not affect mitochondrial integrity, their combined loss results in small body size, low locomotor activity, premature death, ...

nature.com

Supporting #bcfcwomen to victory! 💙 @unibirmingham.bsky.social is the official partner of the Blues now

Such a great pleasure to host @dplamartin.bsky.social at UoB! A day full of cool science about #mitochondria, #endosomes and #mtDNA! Thank you for the visit!

David Pla Martin@dplamartin.bsky.social · last yr.

Lovely visit to @unibirmingham.bsky.social . Thanks to my host @sofiaahola.bsky.social and to the best campus tour guide possible @jonwolfmueller.bsky.social. See you soon!

Great scientist and a person! Can highly recommend! 👏🏻👏🏻👏🏻

Melanie Mittenbühler@mellimittenblr.bsky.social · last yr.

Very happy to share that my research group has launched at the German Diabetes Center (DDZ) in Düsseldorf! We're looking for a PhD student to study the effects of inter-tissue communication on energy balance and metabolic health. Interested? Get in touch! ddz.de/en/job/docto...

Happy International Day of Women and Girls in Science 🔬🧬🧪 There are two of us behing this door 👩🏼‍🔬👩🏻‍🔬 @mashauob.bsky.social and many more @unibirmingham.bsky.social #WomeninSTEM #WomenInScience

Such a pleasure to show around our guest @martazaninello.bsky.social at the beautiful #Edgbaston campus... We did both, the "known" selfie-spots, and some secret ones... @unibirmingham.bsky.social @sofiaahola.bsky.social

Always good to talk more about #mitochondria! It was my great pleasure to have @martazaninello.bsky.social to visit us in @unibirmingham.bsky.social and give a seminar on RNA-binding proteins, axons and mitochondria! 💚 Even Old Joe was #GreenForMito and #mitoaware 💚

🧪Thrilled to share the latest research from the lab of my awesome @umasschan.bsky.social colleague Jessica Spinelli (who isn't on here yet) and collaborators: www.cell.com/cell/fulltex...

Rhodoquinone carries electrons in the mammalian electron transport chain

Valeros et al. identify rhodoquinone (RQ), an electron carrier present in mammalian mitochondria, that can deliver electrons to fumarate instead of O2 as the terminal electron acceptor. The authors de...

cell.com

❄️ No #mitochondria in this one but wishing you all Happy Holidays! ❄️

Stoked to share TWO preprints on mitochondrial pearling! 🎉 We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and @gavsturm.bsky.social et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/