I’m very happy to share a press release about our recent publication on how annulate lamellae build new nuclear pores. 🔬🥳 Grateful to @cnrs.fr for highlighting our work and helping share these findings! 🙏✨

CNRS Biologie@cnrsbiologie.bsky.social · 2w ago

#ResultatScientifique🔎| Comment les cellules construisent-elles les milliers de pores qui assurent les échanges entre le noyau et le cytoplasme ? Dans @natcomms.nature.com des scientifiques révèlent le rôle insoupçonné des lamelles annelées ✍️ @sumaralab.bsky.social buff.ly/qLaqasN

Our new study is out! 🎉🚀 Annulate lamellae aren’t just static reservoirs, they dynamically supply pre-assembled nuclear pores to the nucleus (~1/3 of new NPCs) in normal somatic cells. A new pathway for nuclear pore assembly supporting nuclear expansion.

We are extremely happy to welcome Xiao Lyu to our team! She will pursue her PhD focusing on cancer-specific vulnerabilities. We wish you every success, Xiao! 🤞💪😄

We had a little champagne and some delicious cakes to celebrate the acceptance of our new paper 🤩 We also killed a snowman…🫣😉

I have the great pleasure of hosting Dirk Görlich at the IGBMC this Friday, and I very much look forward to the stimulating and insightful discussions.

IGBMC@igbmc.bsky.social · 9mo ago

FRIDAY LECTURES: Dirk Görlich (Lasker Prize 2025) reveals the “dark proteome” and the selective sorting of molecules within the cell. An exceptional event on Friday, January 9, at 3:00 p.m., IGBMC Auditorium. Organized by Izabela Sumara. A deep dive into the heart of the cell not to be missed!

Secret Santa paid a visit to the Sumara Lab today! 🌟🎅🎄

We are excited to share the revised version of our preprint elucidating the role of Annulate Lamellae in the assembly of Nuclear Pore Complexes #NPCs during early interphase. Big thanks to Junyan Lin and all collaborators for their fantastic work! 🙏🎉

RanBP2-dependent annulate lamellae drive nuclear pore assembly and nuclear expansion

Nuclear pore complexes (NPCs) enable nucleocytoplasmic transport. While NPCs primarily localize to the nuclear envelope (NE), they also appear in cytoplasmic endoplasmic reticulum (ER) membranes calle...

biorxiv.org

Our own Dr. Xiaotian Liu presented a talk on the role of asymmetric dimethylation in nuclear pore assembly at the #EESNucleus EMBO meeting. We couldn’t be prouder 🤓😎😁😁

It was a fantastic #EESNucleus meeting! Thank you so much to the organizers and the entire supporting team 🙏😁

EMBL Events@events.embl.org · 10mo ago

🙌 Hello from #EESNucleus. The organisers Simone Köhler, Patrick Lusk, Thomas Quail, @sarawickstrom.bsky.social and Karo Wolkersdorfer are welcoming all participants to the four day symposium in Heidelberg.

This was indeed a fantastic trip, thanks so much for hosting me! I very much enjoyed learning about fantastic science from you and your amazing @sumatalab.bsky.social team and the great IGBMC community!

Izabela Sumara@sumaralab.bsky.social · 11mo ago

I had the great pleasure of hosting Christian Schlieker @schliekerlab.bsky.social for a seminar at IGBMC @igbmc.bsky.social Thank you 🙏, Christian, for sharing your inspiring science and ideas, and for such engaging discussions with PIs and my team. A truly wonderful visit! 🤩😁

A new photo of my amazing team! 🤩🌟🥰

I had the great pleasure of hosting Christian Schlieker @schliekerlab.bsky.social for a seminar at IGBMC @igbmc.bsky.social Thank you 🙏, Christian, for sharing your inspiring science and ideas, and for such engaging discussions with PIs and my team. A truly wonderful visit! 🤩😁

Minimal CDK and maximal Damien Coudreuse lab! Big congrats 🎉🎈🍾

Snezhka Oliferenko@alebenoit.bsky.social · 11mo ago

Minimal CDK continues delivering 💥 www.biorxiv.org/content/10.1...

Today we welcomed our new postdoc, Dr. Marintia Nava @marintianava.bsky.social, to the lab! We’re so happy to have her on board and wish her the best of luck as she begins her exciting work on Annulate Lamellae. Welcome, Marintia! 😁🤩🌟

Liao et al. @sumaralab.bsky.social show that UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope. rupress.org/jcb/article/... 📕 In our Intermediate Filaments collection: rupress.org/jcb/collecti...

Last day to submit abstracts! Nuclear cell biologists, mechanobiologists, et al. don’t miss out - amazing interdisciplinary line up: computational biology, biophysics, development, genomics - we will have it all!

Jan Lammerding - Lab@lammerdinglab.bsky.social · last yr.

Final call to register and submit abstracts for the @faseborg.bsky.social conference on the Mechanobiology of the Cell Nucleus (#MBNSRC) to be considered for platform presentations. The conference takes place in Melbourne, FL, Oct. 26-30, 2025. See more info at: events.faseb.org/event/Mechan...

Did you know that all nuclear pore complexes (NPCs) are not the same? @luskinglab.bsky.social propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction. www.nature.com/articles/s41...

Nuclear mechanics as a determinant of nuclear pore complex plasticity - Nature Cell Biology

In this Review, Lusk et al. discuss emerging insights into nuclear pore complex variability with regard to composition and dilation state, and propose nuclear mechanics as a key determinant of driving...

nature.com

Why are low-complexity domains (LCDs) in proteins important? #LaskerAward winners Dirk Görlich & Steven McKnight showed that they are critical for intracellular transport and organization. #Lasker2025 #structuralbiology #phaseseparation @mpi-nat.bsky.social

Low-complexity domains: structures & functions

The 2025 Albert Lasker Basic Medical Research Award honors Dirk Görlich and Steven McKnight for discoveries that exposed the structures and functions of low-complexity domains within protein…

youtube.com

We are very happy and proud to celebrate our freshly minted Dr. Xiaotian Liu! 🎉🥂🥳 Many thanks 🙏 to the jury members Ali Hamiche, Lionel Pintard @ccdlab.bsky.social and Charlène Boumendil @charleneboumendil.bsky.social, who also gave a wonderful seminar at the @igbmc.bsky.social

Call for papers: Cell Biology of the Nucleus We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social. Deadline: 3 November journals.biologists.com/jcs/pages/nu...

postdoc opening in vienna: study lipid droplets (LDs) with integrative structural biology, uncover how LD proteins shuttle between cytosol & nucleus to regulate lipid metabolism, organelle architecture and immune response. #VIP3 #lipidtime #cryoEM #coffee training.vbc.ac.at/post-docs/vi...

New study showing the development of pan-Expansion Microscopy by Morgan et al. @luskinglab.bsky.social to reveal the molecular composition and structural plasticity of individual nuclear pore complexes including LINC complex-dependent dilation. rupress.org/jcb/article/...

Important changes on @erc.europa.eu grants‼️Grant structure & most importantly eligibility timeframes (10 years for starting, 15 years for consolidator post PhD-but you can have them only once) changes: erc.europa.eu/news-events/...

Changes to the 2026 and 2027 Work Programmes

With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

erc.europa.eu

Mark your calendars! The next ASCB | EMBO Meeting #CellBio2025 is taking place in Philadelphia, US, 6–10 December 2025: www.ascb.org/cellbio2025/ 🧪 @ascbiology.bsky.social‬ #CellBiology #research

We are hiring #postdocs and #phd students in the areas of #devbio #cellbio #Bioinformatics #mathematics #modeling. This is the full add with details: euraxess.de/jobs/346670 This our lab homepage: www.uniklinik-freiburg.de/walentek-en....

Multiple Postdoc and PhD positions in developmental biology, genetics, bioinformatics and mathematical modeling - Walentek Lab - Freiburg, Germany

University Freiburg Medical Center is a leading institution in biomedical research in the heart of Europe with close associations to other institutions and centers in the tri-national Eucor area (Germ...

euraxess.de

Are you a grad student pursuing the life sciences or biomedical research outside the U.S.? Applications now open for the Angelika Amon Young Scientist Award until June 13. Enter to win $1,000 USD & a chance to present your work & network w/ MIT faculty. buff.ly/F7s94vW

Hi all, my team institut-curie.org/team/fachine... @institutcurie.bsky.social is looking for a Bioinformatician. You can find more details about the position here: euraxess.ec.europa.eu/jobs/344508 Is anyone looking for a job in the lovely Paris?

Extremely excited and happy to welcome a new postdoc Dr Mathieu Meode to the Sumara lab 🤩! We wish him all the best of luck🤞studying biogenesis of #nuclear pores in health and disease 🤓

⏳Only 20 days left to register for #CellCycle2025! June 23–26 at @salkinstitute.bsky.social The US may not be everyone's top travel pick right now—but if you can come, please do. Great science, and a reminder that research is fun and thrives on global collaboration. www.salk.edu/cellcycle2025

Check out our new paper! We identified Smoc2 as an interesting target that is upregulated upon EGFR deletion, driving stemness signatures, reduction in cell size and metabolic rewiring. 💪 🔝👍

EMBO Molecular Medicine@embomolmed.org · last yr.

Online today! 👉 #EGFR controls transcriptional & metabolic rewiring in KRASG12D #ColorectalCancer By D. Krauẞ, @maria-sibilia.bsky.social & colleagues at @meduniwien.ac.at 🗞️ doi.org/10.1038/s443...