Congrats to #ListerFellow David Bending and colleagues on @medresfdn.bsky.social funding to advance safer, more personalised cancer care 👏 David will investigate role of T peripheral helper cells in immunotherapy side effects. @bendinglab.bsky.social www.birmingham.ac.uk/news/2026/bi...

Birmingham researchers receive funding to improve patients’ lives during and after cancer treatment - University of Birmingham

Three University of Birmingham researchers will investigate why cancer immunotherapy can cause harmful side effects and how to predict, prevent and treat them.

birmingham.ac.uk

MRC curiosity-driven research reopens with new approach www.ukri.org/news/mrc-cur... MRC applicant-led funding opportunities reopen 7 Apr, experimental medicine opportunities opening 30 Apr Complete change in selection of project: no boards, shortlisted applicants -> in-person panel interview.

MRC curiosity-driven research reopens with new approach

The Medical Research Council (MRC) unpauses curiosity driven research funding and improves the funding process.

ukri.org

www.bbc.co.uk/news/article...

UK’s £8bn research fund faces “hard decisions” as it pauses new grants

UKRI boss Ian Chapman said it had been told by the government to

bbc.co.uk

How to reconcile the end statement “UKRI’s overall research and innovation budget is rising…” with earlier “we unfortunately expect to make a reduced number of awards to applications currently being assessed” This statement if anything makes things worse www.ukri.org/blog/mrc-fun...

MRC funding update

An update on MRC funding during UKRI’s transition, what’s changing, and the next steps for paused opportunities and reopening timelines.

ukri.org

Has the MRC made a public statement yet

a man is sitting on a swing in the grass

ALT: a man is sitting on a swing in the grass

media.tenor.com

It's today! Our #BSIMidlands25 kicks off with an overview of the history of clinical immunology in the Midlands by Dr Aarnoud Huissoon

We are very proud to introduce our brand new 2025 #ListerFellows! This year there are eight Prize recipients. lister-institute.org.uk/a-warm-welco...

Honoured to receive this prize alongside an inspiring group of scientists. This will support our work to improve mRNA therapies for precision medicine. #mRNA #immunoSky #Science

The Lister Institute of Preventive Medicine@thelisterinstitute.bsky.social · last yr.

We are very proud to introduce our brand new 2025 #ListerFellows! This year there are eight Prize recipients. lister-institute.org.uk/a-warm-welco...

Lovely work!

Worboys Lab@worboyslab.bsky.social · last yr.

Our latest research is now available as a pre-print at BioRxiv. We show that the immune checkpoint receptor TIGIT cannot signal in T cells without simultaneous TCR stimulation. #ImmunoSky www.biorxiv.org/content/10.1...

PD1 & Lag3 regulate TCR signal duration in tolerant CD4 T cells •PD-1 & Lag3 exhibit layered control of CD4 T cell activation •Co-blockade enhances NFAT-dependent TCR transcription •NFAT inhibition reverses functional effects of anti-PD-1&Lag3 doi.org/10.1093/immadv/ltaf015 @imtadvances.bsky.social

Congrats to the team! Very nice study. I find it especially interesting that blocking NFAT can compensate for the effects of anti-PD1/LAG3.

PD1 & Lag3 regulate TCR signal duration in tolerant CD4 T cells •PD-1 & Lag3 exhibit layered control of CD4 T cell activation •Co-blockade enhances NFAT-dependent TCR transcription •NFAT inhibition reverses functional effects of anti-PD-1&Lag3 doi.org/10.1093/immadv/ltaf015 @imtadvances.bsky.social

🔥 Open postdoc position in human inflammation-driven control of infection! 🔥 Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5) Please share!

Our new blog post spotlights the Lister Institute's ties with @unibirmingham.bsky.social, home to Lister Fellows past and present @bendinglab.bsky.social @agagambus.bsky.social @sarahdimeloe.bsky.social sky.social @therad-lab.bsky.social @tunglejic.bsky.social lister-institute.org.uk/shining-a-li...

#Immunology out now @science.org After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/49bKcTG By Jobin, Seetharama, Rüttger et al.

Check out latest work from @bendinglab.bsky.social - new insights into IFNg regulation of TCR signalling! 🧪 #immunosky

Bending Lab UK@bendinglab.bsky.social · last yr.

Now published @cp-iscience.bsky.social Work lead by David Lecky & Lozan Sheriff in collaboration with @therad-lab.bsky.social and @cameron-wraith.bsky.social showing how IFNg augments T Cell receptor signal strength to enhance type 1 Regulatory T (Tr1) cell development www.cell.com/iscience/ful...

Now published @cp-iscience.bsky.social Work lead by David Lecky & Lozan Sheriff in collaboration with @therad-lab.bsky.social and @cameron-wraith.bsky.social showing how IFNg augments T Cell receptor signal strength to enhance type 1 Regulatory T (Tr1) cell development www.cell.com/iscience/ful...

Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans @jem.org rupress.org/jem/article-...

A new paper from #ListerFellow @linterman.bsky.social and colleagues explores the role of tertiary lymphoid structures (TLS) in #bcell immune response. @pnas.org doi.org/10.1073/pnas...

Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS

The lungs are constantly exposed to the external environment and a myriad of antigenic challenges within the air. Chronic exposure to allergens and...

doi.org

What better way to get into that Friday feeling than reading our new paper? First author @hlpeks.bsky.social and I will be doing a tutorial on @arrdept-ucldom.bsky.social next Tuesday lunchtime for those who are interested in reading the highlights 📖

Journal of Experimental Medicine@jem.org · last yr.

Sex hormones and chromosomes work in tandem to impact immune responses, with estrogen influencing class-switched memory B cell frequency exclusively in humans with an XX chromosomal background. From @hlpeks.bsky.social, @bcellsrosser.bsky.social, Coziana Ciurtin et al. rupress.org/jem/article/...

Sex hormones and chromosomes work in tandem to impact immune responses, with estrogen influencing class-switched memory B cell frequency exclusively in humans with an XX chromosomal background. From @hlpeks.bsky.social, @bcellsrosser.bsky.social, Coziana Ciurtin et al. rupress.org/jem/article/...

📣 New Review Alert! Do you think glial cells are simply neuronal support cells in the CNS? Did you know glial cells are integral to barrier organs? Check out our latest review exploring the fascinating crosstalk between glia and immune cells in the gut, lung and skin! #GlialCells #ImmuneSystem

Mucosal Immunology@mucosalimmunol.bsky.social · 2y ago

Glial-immune interactions in barrier organs are reviewed by @franzeprogatzky.bsky.social and colleagues: www.mucosalimmunology.org/article/S193...

Excited for our lab's FIRST paper #ScienceImmunology! 🎉 Led by @categraca.bsky.social & Amania Sheikh, with amazing collabs from Axel Kallies, Dane Newman, & @rickyjohnstone.bsky.social Huge thanks to reviewers & @claireolingy.bsky.social 🙌 #Tpex #onthescoreboard www.science.org/doi/full/10....

Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression

ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer.

science.org

The BSI has grants available for our members who want to help get more people excited about #immunology

British Society for Immunology@britsocimm.bsky.social · 2y ago

Our Communication and Engagement Grant is open to all BSI members who want to take part in #PublicEngagement 🌟 Share your passion, build skills, and make a difference to the world of #immunology 💪 Application deadline: 1 Feb 2025 🗓️ Apply now 👉 bit.ly/3Y9j8gm

⏰ Last few days before the deadline of midday (GMT) Friday 10 January if you are thinking of applying for one of our Medical Research Council fully funded 4 year PhD studentships at our partner institutions @uniofnottingham.bsky.social @unibirmingham.bsky.social or University of Leicester 🧵

great opportunities!

Worboys Lab@worboyslab.bsky.social · 2y ago

Studentships available in the lab in the BBSRC NWD scheme (www.bmh.manchester.ac.uk/study/resear...) 1. Looking at the nanoscopic arrangement of chemokine-matrix interactions (with @douglaspdyer.bsky.social) #ImmunoSky #Immunomatrix

I’m so excited about this project, it’s going to reveal so much about how the glycocalyx works, amazing opportunity!!

Worboys Lab@worboyslab.bsky.social · 2y ago

Studentships available in the lab in the BBSRC NWD scheme (www.bmh.manchester.ac.uk/study/resear...) 1. Looking at the nanoscopic arrangement of chemokine-matrix interactions (with @douglaspdyer.bsky.social) #ImmunoSky #Immunomatrix

BLUESKY MEGA-THREAD Altmetric is thrilled and also LITERALLY RELIEVED to officially announce: We are now tracking research attention as it happens on Bluesky! We have been picking up posts on the site since late Oct. Our team is on Bluesky all day answering questions. Let's get into it!

There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research. A Place of Joy.

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Altmetric@altmetric.com · 2y ago

There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research. A Place of Joy.