Looking forward to sharing this story in person at #RNASociety on Friday! I'm giving a talk at the RNA and Disease session and Liza will have a poster (ID 528) on Friday evening.

Cassandra Hayne@cassandrahayne.bsky.social · 2mo ago

🚨The lab's first research paper is In Press at JBC! Congrats Liza and Magda!! Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization - Journal of Biological Chemistry www.jbc.org/article/S002...

🚨The lab's first research paper is In Press at JBC! Congrats Liza and Magda!! Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization - Journal of Biological Chemistry www.jbc.org/article/S002...

Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization

The Target of EGR1 (TOE1) gene encodes the TOE1 deadenylase, which is essential for the maturation of Pol-II transcribed snRNAs in humans. Over a dozen missense mutations in the TOE1 gene have been li...

jbc.org

1/8 I am excited to share a new paper from the education side of the lab. There is a lot of anxiety that genAI tools will jeopardize learning gains from homework assignments. Using Bloom's Taxonomy, we analyzed where genAI succeeds and where it struggles. journals.plos.org/plosone/arti...

Designing life science assessments in the era of generative artificial intelligence

Generative artificial intelligence (GAI) algorithms have the potential to reshape education. Though GAI may help democratize access to education, it also presents many challenges for educators. Alread...

journals.plos.org

Heads up all Junior RNA Scientists - March 31st is the deadline for poster abstract submission and early bird registration for the 2026 Annual RNA Society Meeting in Montreal! Don't miss out, we have an exciting panel and fun events planned!

RNA Society@rnasociety.bsky.social · 4mo ago

Poster abstracts and early bird registrations for the 31st Annual Meeting of the RNA Society are due by March 31st! RNA 2026 website: rnasociety.org/conferences/ #RNA26

As a child, @phosphotig.bsky.social dreamed of being an astronaut, but her curiosity led her to scientific research. Now, she leads her own lab at UNC-Chapel Hill, & studies oxidative stress to find better therapies for triple-negative breast cancer. #WomensHistoryMonth www.asbmb.org/asbmb-today/...

Learning, leading and lifting others

Tigist Tamir’s journey from aspiring astronaut in Ethiopia to cancer researcher at the University of North Carolina highlights the power of mentorship, persistence and curiosity in shaping a scientifi...

asbmb.org

NIGMS is signed onto the F31 NOFO. grants.nih.gov/grants/guide...

A piece of good news for basic scientists in training!

I-75 Scientist@flscitriguy.bsky.social · 5mo ago

NIGMS is signed onto the F31 NOFO. grants.nih.gov/grants/guide...

Got my first conference attendee scam. Assume they targeted names on the website for: #RNASociety See lots more of this lately.

I was on Capitol Hill today with @asbmb.bsky.social urging lawmakers to support strong federal investment in scientific research and training. Also to support : predictable and sustained funding. #ASBMBAdvocates #ScienceServesUsAll

Folks from @rnasociety.bsky.social advocating for basic science research funding #ASBMBAdvocates @uwmadisonrna.bsky.social @cassandrahayne.bsky.social

Folks from @rnasociety.bsky.social advocating for basic science research funding #ASBMBAdvocates @uwmadisonrna.bsky.social @cassandrahayne.bsky.social

New and competitive renewal awards Fewer than 40 new awards were made in the past week, compared to over 100 the previous week. 5/9

This flattening may be due to the apportionment issue covered in the recent Nature story. www.nature.com/articles/d41... 3/9

White House stalls release of approved US science budgets

The US Congress rejected sweeping cuts to science agencies. But the NIH, the NSF and NASA have had their spending slowed.

nature.com

All projects The fiscal year 2026 appears to be flattening out a bit in the past week. 2/9

New preprint alert! We share some of our recent insights about sequence similarity in IDP protein families and find that conservative substitutions in well-conserved binding motifs of the CITED proteins have big impacts on their ensembles and functions. Take a look! www.biorxiv.org/content/10.6...

A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV

www.statnews.com/2025/12/08/t...

NIH shut out hundreds of young scientists from funding to start their own labs

Special Report: The NIH has shut out hundreds of young scientists from funding to start their own labs.

statnews.com

Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...

What are people using for calling m6A from pacbio revio data? This is for analysis of fiberseq library. Any suggestions appreciated, we are newbies with m6A analysis!

Listed are some of the many NIH research training programs that were terminated! Together, these programs supported thousands of trainees, whose careers are now in limbo. Such a great loss for discovery and innovation. We must protect our next generation of scientists! #HandsOffNIH #ProtectScience

27 UNIHTED@27unihted.bsky.social · 12mo ago

We LOVE our trainees ! From @nihvigils.bsky.social today ❤️❤️

It bears repeating that nearly the entire US enterprise in science and technology has been irreversibly gutted. This is shocking. All this loss has occurred without any real benefit to the average US citizen. Except we now have the biggest, best funded secret police force perhaps ever. Yay for us!

I’ve had a lab for less than 3yrs. In that time the costs of many science reagents have grown faster than inflation. I ordered an antibody today that I paid $383 for in 2023- today with a good promotion, I paid $467. Tariffs on top of that. Other easy examples: Grids are up about 30% Gloves up 25%

A joint statement with @savehealthresearch.bsky.social on the supreme courts decision today that will pave the way for hundreds of millions of dollars in NIH grant terminations. We are heartbroken and stand with the extramural community during this devastating time.

There is no solace for NIH funded researchers in this Supreme Court decision. Grants that were ripped away on dubious grounds, restored by a reasonable judge are now again terminated by an out-of-control Supreme Court. Labs will shutter, people will lose jobs. www.reuters.com/world/us/us-...

US Supreme Court lets Trump cut diversity-related NIH grants

The U.S. Supreme Court let President Donald Trump's administration on Thursday proceed with sweeping cuts to National Institutes of Health grants for research related to racial minorities or LGBT people, part of his crackdown on diversity, equity and inclusion initiatives and transgender identity.

reuters.com

Why would anyone want to be a scientist? Check out our new Essay from Martin Schwartz: journals.biologists.com/jcs/article/...

I think a good rule of thumb is to spend at least as much time thinking about your data as you did obtaining it. It's common for people to spend a lot less time thinking than doing which gives rise to all kinds of problems.

New Notice about No-Cost Extensions... grants.nih.gov/grants/guide...

There’s a nonzero chance you will die from a cancer that could have been curable because people who couldn’t pass 7th grade biology and are scared of things like “mRNA” and “riboflavin” and “walkable cities” decided to make their ignorance everybody else’s problem

Stand Up for Science!@standupforscience.net · last yr.

Over 120 mRNA cancer trials are now at risk as the Trump admin cuts funding & tells researchers to scrub “mRNA” from grant proposals. What started as COVID fearmongering is now derailing life-saving cancer research. Hope remains - but scientists say time is running out. zurl.co/YBGNy

Grant terminations have grabbed the headlines and have seen legal action, but even more damaging to the US research enterprise has been the massive decrease in number of research grants issued by federal agencies NIH has seen a decrease of 57% in the number of awards & 63% in value compared to FY24