“Trump has rejected disaster aid for Democratic-run states at the highest rate in the 47-year history of the Federal Emergency Management Agency.” Right now people in blue states are basically paying federal taxes as if they’re colonized territories of red states. www.politico.com/news/2026/03...

Absolutely sobbing by the end of this story. A must-read. Very interested to see what impact this has on the gene-editing field. www.science.org/content/arti...

Exclusive: Death of girl in Chinese gene-editing trial was never made public

Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals

science.org

Of all the harm this administration has done to US science, today's proposed changes to the way federal grants are awarded and administered is the most damaging yet. The text of the federal register document is impenetrably tedious by design, so here's an excellent summary of what it says.

elizabethginexi.bsky.social@elizabethginexi.bsky.social · 2mo ago

Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...

Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!

More on the destruction of US science. www.chronicle.com/article/they...

They Got the Best NIH Scores of Their Careers. A Year Later, They Still Don’t Have Funding.

The NIH’s spending on new medical research is significantly slower than in previous years, leaving confused scientists in the lurch.

chronicle.com

Well. This is startling. “At least one of the NIH’s 27 institutes and centres has lost so many GMSs that it has asked early-career researchers, including postdocs and graduate students, who work in the NIH’s own labs to consider working temporarily as a GMS on a volunteer basis”

Jeremy Berg@jeremymberg.bsky.social · 3mo ago

@maxkozlov.bsky.social covered the staffing shortages at NIH. www.nature.com/articles/d41... 1/3

I am hiring a popgen postdoc! Looking for a creative scientist to join us at USC to investigate recessive variation and complex traits in model or non-model species. The project is funded by a multi-year NIH grant, contract can be renewed. Job add & details 👇🏽 usccareers.usc.edu/job/los-ange...

Check out our newly published work in #GENETICS!

Genetics Society of America@genetics-gsa.bsky.social · 5mo ago

New in #GENETICS: A systematic disruption of small RNA-binding capacity of multiple Argonaute proteins identifies a critical role of small RNA loading in maintaining the stability and localization of Argonaute proteins during #Celegans germline development. buff.ly/Aguq9c5

New in #GENETICS: A systematic disruption of small RNA-binding capacity of multiple Argonaute proteins identifies a critical role of small RNA loading in maintaining the stability and localization of Argonaute proteins during #Celegans germline development. buff.ly/Aguq9c5

NIGMS is signed onto the F31 NOFO. grants.nih.gov/grants/guide...

New and competitive renewal awards Fewer than 40 new awards were made in the past week, compared to over 100 the previous week. 5/9

Been hearing some horrifying chatter about dealing with the new #NIH common form and #ScienCV system, so I put together a short video with some tricks for mitigating some of those pain points. Hope it helps? 🧪 open.substack.com/pub/emptymod...

Dealing with ScienCV formatting

Some tips for composing and making your new NIH biosketch not look like garbage

open.substack.com

Another YouTube Tutorial – This one on Proximity Labeling and connected to our recent EMBO J. paper (PMID: 41381733). This is a recording of a talk at the IDeA National Resource for Quantitative Proteomics in Little Rock AR. One of the top facilities in the country! www.youtube.com/watch?v=0T9P...

Core Directors' Symposium - 2025 - David Fay

YouTube video by IDeA National Resource for Quantitative Proteomics

youtube.com

Greetings! I decided to make a YouTube video of my AlphaFold workshop that I've given a few times in the past year. Caveats aside, people seem to find this useful for thinking about how to model protein interactions and how to interpret various AF outputs 1/2 www.youtube.com/watch?v=u63o...

David's AlphaFold WorkShop 2026

YouTube video by David Fay

youtube.com

New review out! 🧬🪱 How do Argonautes bind the right small RNAs? We synthesize how small RNA features, Argonaute properties, chaperones, and subcellular organization shape small RNA binding specificity. rnajournal.cshlp.org/content/earl...

Y'all, I just got out of the NSF-BIO webinar where they explained changes to peer review. It's not good. 🧪 scienceforeveryone.science/changes-to-n...

Changes to NSF peer review

They're not good. At all.

scienceforeveryone.science

Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵 www.anthropic.com/news/claude-...

Claude for Life Sciences

Discover how Claude accelerates life sciences research with new scientific connectors, skills, and improved performance for drug discovery and clinical work.

anthropic.com

Dear all, A scientist from UNC Chapel Hill, Paul Maddox, is running for congress in NC for a seat currently held by a republican. If you care about science (and democracy) please consider donating to his campaign #Standupforscience secure.actblue.com/donate/paul-...

Donate to Paul Maddox for Congress in NC 11

Paul is running for Congress because there’s a sickness in Washington, and no one is working to cure it.

secure.actblue.com

Today was a hard day for Ph.D. students who found out that they can no longer apply for NSF's prestigious Graduate Research Fellowship Program. "Devastating“ was how one student described it to me. #GradSchool #NSFGRFP www.science.org/content/arti...

‘Completely shattered.’ Changes to NSF’s graduate student fellowship spur outcry

The announcement comes months later than usual, leaving many would-be applicants stranded

science.org

I did a thing. I wrote a textbook about #RNA. I wrote it so that those without formal science training could understand what RNA is and how it is used in medicine. It releases in the US and Europe on September 8th. www.worldscientific.com/worldscibook...

Sign the petition to call for the removal of RFK, Jr. www.standupforscience.net/rfk-impeachm...

Sign the IMPEACH RFK Citizens' Petition to Congress — STAND UP FOR SCIENCE

Join with us to sign our Citizens' Petition to the US Congress to choose the people over Trump and Impeach RFK Jr Now!

standupforscience.net

The US could see a 30-40% decline in new international student enrollment, resulting in nearly $7 billion in lost revenue and more than 60,000 fewer American jobs. https://www.nafsa.org/fall-2025-international-student-enrollment-outlook-and-economic-impact

Suspension of all grants to UCLA www.latimes.com/california/s...

Trump freezes $200 million in UCLA science and medical research funding, citing antisemitism

The Trump administration has frozen roughly $200 million in National Science Foundation, National Institutes of Health and other federal agency-funded research at UCLA, citing allegations the school d...

latimes.com

A little known - but hugely consequential - part of the government’s changes to science funding: open.substack.com/pub/sciencea...

A Quiet Policy Shift That Could Devastate American Science

Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university

open.substack.com

This is a catastrophe in the making gizmodo.com/rfk-jr-says-...

RFK Jr. Says AI Will Approve New Drugs at FDA 'Very, Very Quickly'

gizmodo.com

Go worms! #worm25

Huge thanks to Cathy Savage-Dunn @cswormlab.bsky.social and Baris Tursun @baristursun.bsky.social for an amazing #worm25 !! I want to call out the OUTSTANDING meeting they created! Talks and posters were A+++. Most of all they brought us together in one of the most challenging times we've had.

c. elegans, ba-ba-bah #worm25

CNN story updated with specifics: "the administration is specifically considering a full termination of federal grant funding for the University of California and California State University systems. A White House official said Friday afternoon that no final decision had been made on the cuts."

Trump preparing large-scale cancellation of federal funding for California, sources say | CNN Politics

The Trump administration is preparing to cancel a large swath of federal funding to California, an effort which could begin as soon as Friday, according to multiple sources.

cnn.com

Dear lord: "On Capitol Hill, at least one committee was told recently by a whistleblower that all research grants to the state were going to be cancelled." The U of Cali system alone accounts for $4B+ per year in federal R&D. If true, let's hope for another all-or-nothing fight like Harvard's.

Carl Quintanilla@carlquintanilla.bsky.social · last yr.

(CNN) — The Trump administration is preparing to cancel a large swath of federal funding for California, an effort which could begin as soon as Friday, according to multiple sources. @cnn.com www.cnn.com/2025/06/06/p...