How does the brain represent the value of knowledge? In our paper--out now at Nature Neuroscience--we identify a representation of intrinsic information value within neural population structures in the orbitofrontal cortex in mice. www.nature.com/articles/s41593-026-02377-y #neuroskyence 🧠🧪 (1/8)

Representations of the intrinsic value of information in mouse orbitofrontal cortex - Nature Neuroscience

Mice are motivated to seek information of no extrinsic value. Recording neural activity in orbitofrontal cortex reveals a representation of the value of information that is distinct from the value of ...

nature.com

Our work on goal-directed theta sweeps is out! We found two different types of theta sweeps in the rat hippocampus. During random foraging, left-right alternating sweeps dominated (Vollan, 25). However, during memory-guided navigation sweeps pointing to hidden goal locations emerged with learning.

Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr

Thrilled to see our paper published! I’m deeply grateful to the amazing @ggirardeau.bsky.social for trusting me to develop and carry it out. Many thanks as well to @azulsilva.bsky.social , @belalima-paiva.bsky.social and Eleonore for driving this work forward together. www.nature.com/articles/s41...

Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience - Nature Neuroscience

Synchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than positive ones.

nature.com

🧠 Looking forward to Mark Brandon’s visit ! His work on Head Direction coding changed how we think of the neural compass: Network gain maintains a memory trace of previous experience. 🗓️ Join us for his seminar on April 3rd at 11h30 📍45 rue des Saints-Pères, Paris

Paris Neuro Calendar@neurocalendar.bsky.social · 5mo ago

Mark Brandon - How the brain stays oriented My research uses the brain’s navigation system as a window in Friday, April 3, 2026 - Université Paris Cité R229

Hi BlueSky — I’m bringing over an old SciTwitter thread series exploring how beautifully the vestibular system works from a systems and computational neuroscience perspective. Chapter 1 coming shortly! I’ll keep all chapters threaded below.

'The postsubiculum as a head-direction cortex' by Adrian Duszkiewicz, Desdemona Fricker, Andrea Burgalossi & Adrien Peyrache @adrian-du.bsky.social @desdemonafricker.bsky.social @apeyrache.bsky.social www.cell.com/trends/neuro...

New paper alert! 🚨 We found that the brain's compass is remarkably stable at two scales 1️⃣ the system maintains its internal organization for weeks 2️⃣ It "remembers" its orientation for weeks, even after a single visit This may be key to how the brain aligns its other maps. Paper: rdcu.be/e3waP

La @semaineducerveau.bsky.social arrive bientôt au SPPIN ! Nous avons le plaisir d’accueillir une conférence suivie d’une visite du laboratoire par @uligraupner.bsky.social dédié aux approches optogénétiques pour comprendre les circuits neuronaux et le comportement.

We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:

Edvard I Moser@edvardmoser.bsky.social · 6mo ago

The hippocampal map has its own attentional control signal! Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉 www.biorxiv.org/content/10.6... 🧵(1/6)

If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd parisneuro.ovh

Active locomotion predictively rescues head direction attractor dynamics in head-fixed mice https://www.biorxiv.org/content/10.64898/2026.01.12.698940v1

Fantastic work!

Desdemona Fricker@desdemonafricker.bsky.social · 7mo ago

Coincidence of thalamic HD signal and retrosplenial visual input is detected in the Presubiculum! 🎯 This may be the neuronal basis for landmark anchoring of the HD signal. Pleased to announce the VOR is now available elifesciences.org/articles/92443 Congrats first author Louis Richevaux 🙌

I’m very happy to share the latest from my lab published in @Nature Hippocampal neurons that initially encode reward shift their tuning over the course of days to precede or predict reward. Full text here: rdcu.be/eY5nh

1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here: rdcu.be/eX1L4

Plastic landmark anchoring in zebrafish compass neurons

Nature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.

rdcu.be

Coincidence of thalamic HD signal and retrosplenial visual input is detected in the Presubiculum! 🎯 This may be the neuronal basis for landmark anchoring of the HD signal. Pleased to announce the VOR is now available elifesciences.org/articles/92443 Congrats first author Louis Richevaux 🙌

Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex

Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal com...

elifesciences.org

1/n: A new collaborative preprint from the lab to start the year: "A multi-ring shifter network computes head direction in zebrafish" together with Siyuan Mei, Martin Stemmler and Andreas Herz from the LMU, Munich.

1. New preprint resolving a conundrum in systems neuroscience with an AI scientist, and humans Reilly Tilbury, Dabin Kwon, @haydari.bsky.social, @jacobmratliff.bsky.social, @bio-emergent.bsky.social, @carandinilab.net, @kevinjmiller.bsky.social, @neurokim.bsky.social www.biorxiv.org/content/10.1...

Characterizing neuronal population geometry with AI equation discovery

The visual cortex contains millions of neurons, whose combined activity forms a population code representing visual stimuli. There is, however, a discrepancy between our understanding of this code at ...

biorxiv.org

📢 We are organising the Senses in Motion conference for the third time, and we are now accepting abstracts for posters or talks. Deadline for abstracts: 19 December Conference dates: 18–21 May 2026 Location: Harnack House, Berlin Register via this page👇 sensesinmotion.org #neuroskyence #neurosky

No GPS in the head? Path integration by entorhinal grid cells without the grid pattern. Interesting paper from Heidelberg. www.nature.com/articles/s41...

Grid cells accurately track movement during path integration-based navigation despite switching reference frames - Nature Neuroscience

Grid cells do not maintain a stable pattern during a self-motion-based task, but track animal movement in multiple local reference frames and reanchor to task-relevant objects, thus estimating local r...

nature.com

Neuroscience projects last several years, and you are usually a bit jaded by the time you wrap it up. Not this one– spending several months on an island in the middle of nowhere, away from all the craziness of the world reminds you how beautiful the world really is. www.youtube.com/watch?v=46sv...

Bat Island: The New Era of Science

YouTube video by Weizmann Institute of Science

youtube.com

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

The postsubiculum as a head-direction cortex

The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…

sciencedirect.com

🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇 kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩

Adrian Duszkiewicz@adrian-du.bsky.social · 10mo ago

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

Thanks to the Capitainerie de l’Isle and to Nathalie for hosting our exhibit ✨

Travel awards are available for undergraduate students looking to attend #Cosyne25! The application is short, and the deadline is Nov 12. @cosynemeeting.bsky.social Application: shorturl.at/6NEyk More info: www.cosyne.org/travel-grants (1/2)

Dear #ParisNeuroscience community, here is the schedule of the upcoming 'Neural Networking Night' season !

2/6 Recording in decision-making regions from many neurons at once revealed the neurons' collective evolution as decisions were made Each decision had two phases: first, neural state was sensitive to sensory inputs; then, trajectories in neural state space turned and became insensitive to inputs.

How does the brain decide? 🧠 Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc. After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up. rdcu.be/eGUrv

Transitions in dynamical regime and neural mode during perceptual decisions - Nature

Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...

nature.com

🚨New preprint alert! The thalamus has long been seen as a relay of sensory signals to cortex. But could it also generate its own structured activity? Our study explores this question in the head-direction (HD) system. Some explanation 🧵👇 1/13 www.biorxiv.org/content/10.1...

Coherent dynamics of thalamic head-direction neurons irrespective of input

While the thalamus is known to relay and modulate sensory signals to the cortex, whether it also participates in active computation and intrinsic signal generation remains unresolved. The anterodorsal...

biorxiv.org

Voir Montrer Regarder 👀 Observer Mesurer Vérifier #SciArt If you are in Paris in September check out our exhibit “Regards Croisés”: Come for the Art, stay for the Science ! This scientific outreach event is supported by @c-brains.bsky.social, @sppin-cnrs.bsky.social and the Capitainerie de l’Isle.

Saints-Pères Paris Institute for the Neurosciences@sppin-cnrs.bsky.social · last yr.

🎨🔬 Quand l’art rencontre la science ! Le SPPIN est heureux de vous annoncer l'Expo #SciArt “Regards Croisés” avec l’artiste Sophie Sainte-Marie-Heim et notre collègue @desdemonafricker.bsky.social 🗓 22–28 sept. 2025 📍 Capitainerie de l’Isle, 26 rue Chanoinesse, Paris 4e Venez nombreux !