Structural biology postdoctoral position open in my lab--apply now! For more information about the lab, see www.umassmed.edu/munsonlab/. Interested candidates should apply through the University of Massachusetts Chan Medical School jobs portal (www.ummsjobs.com/job/11668/).

Munson Lab | Home | BMB | UMass Chan Medical School

The Munson Lab researches the mechanistic basis for the regulation of spatial and temporal specificity in membrane trafficking in the Biochemistry & Molecular Biotechnology Department at UMass Chan Me...

umassmed.edu

The Biophysical Society Membrane Fusion, Fission, and Traffic Subgroup is hosting an exciting set of 4 virtual talks on Wednesday September 16th starting at 1 pm Eastern Time on clathrin structure and dynamics. Please join! www.biophysics.org/outreach/sub...

Piezo1 balances focal and reticular adhesions to enable EGFR clathrin-mediated endocytosis https://www.biorxiv.org/content/10.64898/2026.08.21.746250v1

Endocytic clathrin coats are surprisingly dynamic: triskelia turn over in seconds. How is the turnover regulated and what is it for? Read Anne-Laure Boinet's preprint with @rouxlab.bsky.social www.biorxiv.org/content/10.6...

Activity-dependent astrocytic cholesterol release fine-tunes modes of synaptic exo- and endocytosis. New study from Jongyun Myeong and Vitaly A. Klyachko @washumedicine.bsky.social: rupress.org/jcb/article/... #CellSignaling #Neuroscience

Take a look at our new paper on the structure of the EHD2 that, upon oligomerization, forms rings that remodel the plasma membrane and form caveolae. Beautiful work by Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff & Oliver Dumke's team; take a look: www.nature.com/articles/s41...

Western North Carolina

www.biorxiv.org/content/10.6... Layered helical order reveals assembly states in podosome actin networks

The heart has a mysterious and complex nervous system of its own. Scientists are starting to reveal its secrets go.nature.com/4wl3z70

The heart has a ‘little brain’ — and it protects against stress

A subset of cardiac neurons keep the heart from malfunctioning in stressed mice.

go.nature.com

Here's a classic for Sci-Fi Cutaway Saturday: A 1970s cutaway view of a Toroidal Colony, by NASA artist Rick Guidice

Doors in Pisa @taraska.bsky.social

De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging | Science www.science.org/doi/10.1126/...

De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging

Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...

science.org

Looking for poetry in graphic novel form? We suggest the graphic novel adaptation of The Odyssey by @garethhinds.bsky.social. #AskALibrarian

The Odyssey — Multnomah County Library

The Odyssey — Hinds, Gareth, 1971- — Retells, in graphic novel format, Homer's epic tale of Odysseus, the ancient Greek hero who encounters witches and other obstacles on his journey home after fighti...

multcolib.bibliocommons.com

Excited to share our new paper, now published in Nature Cell Biology! 🎉 We asked a fundamental question in cell biology: How do cells maintain polarity while migrating? Especially how do cancer cells navigate confined spaces? www.nature.com/articles/s41556-026-01981-1

CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration - Nature Cell Biology

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

nature.com

Glenstone, Potomac, MD

I had a ton of fun the other day talking with @nonresidentdesi.bsky.social and @scifri.bsky.social 's Flora Lichtman and Rasha Aridi about murderous microbes and the things that we are trying to learn from them. Happy for the opportunity to bring some new awareness to the world of protists!

Science Friday@scifri.bsky.social · 2mo ago

Researchers like Ben Larson and Glen D’Souza are piecing together the world of killer microbes, including why they turn on each other and if their tiny weapons could be harnessed to fight disease. Listen to the podcast now: www.sciencefriday.com/segments/kil...

Researchers like Ben Larson and Glen D’Souza are piecing together the world of killer microbes, including why they turn on each other and if their tiny weapons could be harnessed to fight disease. Listen to the podcast now: www.sciencefriday.com/segments/kil...

Swords, cannibalism, poison: inside the world of killer microbes

Some microbe species have evolved to stab, bomb, cannibalize, or poison each other. Can we harness their weapons for good?

sciencefriday.com

Native maypop purple passionflower, Maryland

How does a cell remodel the ER membrane into a lipid droplet? Excited to share our new bioRxiv preprint, where we find that regulated opening of the seipin ring defines a functional ER–lipid droplet interface — and identify SMLR1 as a regulator of this transition. www.biorxiv.org/content/10.6...

Looking for your next step after a BS/BA or MS in biology, cell biology, biochemistry, or a related field? My NIH lab in Bethesda, MD is looking for a Lab Manager/Technical Specialist. Interested in basic research? Please email me directly or learn about our lab here: irp.nih.gov/pi/justin-ta...

ICYMI: New Online! Caveolae mechanics in cellular functions and disease

Caveolae mechanics in cellular functions and disease

Nature Reviews Molecular Cell Biology, Published online: 02 June 2026; doi:10.1038/s41580-026-00964-2Caveolae are membrane invaginations that facilitate cell signalling and act as membrane reservoirs. This Review discusses recent insights into caveolae assembly and disassembly, their roles in mechanotransduction and how impaired caveolae mechanics contribute to human disease.

dlvr.it

🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars Damián Martínez & Bruno Saraiva, inaugural preprint of @mariodelr.bsky.social new lab www.biorxiv.org/content/10.6...

Mario Del Rosario@mariodelr.bsky.social · 3mo ago

Congratulations to Damián Martinez, Bruno Saraiva, @taylashakespeare.bsky.social, @wmarkbates.bsky.social, Dylan Owen, @christlet.bsky.social and @henriqueslab.bsky.social We hope VLab4Mic helps researchers design better experiments and ask better biological questions 💻 vlab4mic.henriqueslab.org

Huge thank you to the labs of @christlet.bsky.social, Dylan Owen and @wmarkbates.bsky.social, and to Tayla Shakespeare, who helped us make it happen. #VLab4Mic also heavily uses data from @rcsbpdb.bsky.social, @jonasries.bsky.social and @taraska.bsky.social

Better vitrification = better cryo-ET. We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science. Apply here: bit.ly/4uip6eJ

And now it's out! Happy that PNAS selected for the cover this SEM image snapped by @samjlord.bsky.social, one of the most evocative visualizations of Euplotes that I have ever encountered. www.pnas.org/doi/10.1073/... Stay tuned for what is shaping up to be some fascinating follow-up in the lab...

Ben Larson@blarson.bsky.social · last yr.

What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells? www.biorxiv.org/content/10.1... Video by Vittorio Boscaro. 1/n

Bay Bridge, Maryland

A new paper in #ScienceSignaling visualizes the delicate ebb and flow of receptors within neurons via the unusual process of transcytosis—helping answer how these cells maintain their function and connectivity in vivo despite their spindly, elongated nature. https://scim.ag/4dlUGl8

Transcytosis-mediated anterograde transport of the receptor TrkA mediates the formation of presynaptic sites in sympathetic neurons

Sympathetic innervation requires transport of TrkA from the soma surface to the axon.

scim.ag

Some moments between teaching microscopy at @mblscience.bsky.social in Woods Hole.

It was an honor to hear Prof. Sarah Veatch, PhD, deliver yesterday’s Inoué Lecture, discussing how spatiotemporal pair-correlation analysis can recover nanoscale membrane organization in live-cell single-molecule localization #microscopy despite diffusion and molecular motion. #MBL 🌊 #AQLM 🧫