Registration is now open for the LGBTQ+ in STEM Workshop! 22nd-23rd September, Cambridge. Excellent speaker line-up confirmed, with subsidised accommodation and travel bursaries. Come down, share your experiences of being queer in STEM www.outsavvy.com/event/35459/... @lgbtqstemworkshop.bsky.social

We are very excited to present spatial-spectral single-molecule microscopy. We use spatial patterning of filters on commercial cameras to enable multiplexing and spectroscopy. We really put the technique through its paces, and it did everything we threw at it! www.biorxiv.org/content/10.6...

Delighted to share our preprint describing COMET, a new approach to drift correction for #SMLM, which performs exceptionally well in practice. Check out the benchmarking results compared to other methods! :) Thanks to @lreinkensmeier.bsky.social for a superb effort. www.biorxiv.org/cgi/content/...

Your Party's new slogan "It's Your Party, so cry if you want to"

rich dudes got freakier after butlers fell out of fashion, like say what you will about having domestic servants but clearly it was some sort of moderating force on old rich dudes having a fancy man follow you around saying shit like "oh dear sir, that wouldn't be very becoming"

Thrilled to see our recent preprint on tipping points in neurodegeneration highlighted on Alzforum! Read it here: www.alzforum.org/news/researc.... Many thanks to Jessica Shugart for the engaging coverage, and to everyone involved in this exciting project at the @ukdri.ac.uk and elsewhere!

www.nature.com/articles/s41... It's out at last! Work that I was totally privileged to be a part of led by @becs-andrews.bsky.social, with @jcbreiter.bsky.social @stevethechemist.bsky.social and funded by @asapresearch.parkinsonsroadmap.org

Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue - Nature Biomedical Engineering

An optical detection and analysis platform quantifies aggregate density, distribution and size in fluorescently labelled post-mortem human brain tissue.

nature.com

Please share: The application for Les Houches is open (until Oct 31) fluorescenceleshouches.wordpress.com *This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!* PS: no fees this year, you just need to get there, that's all!

French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026"

March 15-20 2026, Les Houches, France

fluorescenceleshouches.wordpress.com

I am finding the fact that "is it acceptable and proportional to call for trans women to be assaulted in public" is now a subject of public debate in the UK really very upsetting.

Out now on biorxiv! Excited to share our latest collaborative work investigating the earliest stages of Parkinson’s disease. www.biorxiv.org/content/10.1... Thanks to all the amazing co-authors Melissa Grant-Peters @jsbeckwith.bsky.social @stevethechemist.bsky.social Mina Ryten Sonia Gandhi

Single-Molecule Friends! Just 10 more days to apply for an exciting joint postdoc with @KlenermanLab, feel free to research out www.ch.cam.ac.uk/job/52425

Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.08.25.671921v1

Build microscopes, solve immunology (kinda)... come and work with us! We have an exciting collaborative postdoc position in the group. www.cam.ac.uk/jobs/postdoc...

Cool work from a cool lab!

Susan Cox@micoxscopy.bsky.social · 12mo ago

How do you quantify cell structures which are deformed between different observations? Our preprint shows how to perform Simultaneous QUAntification of Structure and Structural Heterogeneity (SQUASSH) on 3D fluorescence microscopy data. (1/5) www.biorxiv.org/content/10.1...

Please repost: PhD position with my lab and @weisslab.bsky.social in a great collaboration on bacterial adhesion #microsky. See drive.google.com/file/d/1GJD4...

Hello microscopy and imaging experts and enthusiasts! We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English). Please apply and/or repost! jobs.unige.ch/www/wd_porta...

Why have I done this ridiculous pose

Martijn Zwijnenburg@zwijcompchem.bsky.social · last yr.

Joseph Beckwith from Cambridge gave the first invited talk of the 2nd day of the @rsc-photochem.bsky.social ECR meeting talking about multicolour single molecule spectroscopy. #chemsky #fluoresence

Excited to share some recent work tracking the 3D movement of individual molecules inside the organelles of living cells (💡+ 🦠 + ⚽️💨) with the best team @joechambers.bsky.social @jamesdmanton.bsky.social @jsbeckwith.bsky.social @dgershlick.bsky.social @stevethechemist.bsky.social

bioRxiv Biophysics@biorxiv-biophys.bsky.social · last yr.

Volumetric single-molecule tracking inside subcellular structures https://www.biorxiv.org/content/10.1101/2025.06.09.658280v1

The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology. Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at bsmbc@icloud.com. Fee waivers and bursaries available. ! Please share widely !

www.rsc.org/events/detai... Come to this meeting magnificently organised by @rsc-photochem.bsky.social! Abstract deadline May 30, conference is 26–27 June in London, and I am baffled and happy to be an invited speaker alongside some really great people. #photochem #photophysics #microscopy

Section 28 was "the law" too - that doesn't change the fact that the people who supported it were doing so out of bigotry.

Today, thousands gathered across the country - from Hastings to London to Glasgow - to say: we will always stand with trans people. Trans rights are human rights. 🏳️‍⚧️

🚨We have a 4-year ERC-funded PhD position available in the beautiful city of Leuven, Belgium, for building artificial nanomachines in lipid membranes. Check out the details and apply here: www.kuleuven.be/personeel/jo... Feel free to email me for more information!

Today we share our Collection on protocols describing how to build and operate a broad variety of microscopy setups. Let us know which one is your favourite microscope? 🧪 🔬

Microscopy setup protocols

A collection of Protocols and Tutorials covering a range of microscopy approaches, and including the build of microscopy setups and the use of microscopy ...

bit.ly

A fringe group of bigoted weirdos have dragged British media, government, and law into their hateful obsession with trans people. Grim, depressing, and dangerous. Everyone with power in the UK who's played along should be ashamed of themselves.

Hi all---I sadly cannot make it to #FOM2025, would anybody want to take my registration? Feel free to ping me on here/forward to possibly interested people.

Just had the pleasure to experiment with a camera targeting the astronomy market, but offering great value for microscopy. Cooled, low noise (<1.5 e read-noise), high QE cameras that work with Micro-Manager can be bought for ~$1k: nicost.github.io/microscope-t...

Do you want to learn #BioimageAnalysis? Do you want to strengthen your skills? We're thrilled to announce the #NEUBIAS Pasteur Course on Bioimage Analysis - May 2025! in @pasteur.fr Paris! research.pasteur.fr/en/course/ne... Details are on the page linked here, some info below 👇

NEUBIAS Pasteur course on Bioimage Analysis - 2025 - Research

Topics The exact schedule is still being finalized. Here is a description of the course content. Both tracks of the course have a specific focus on hands-on and interactive tutorials. They are meant t...

research.pasteur.fr

Microscope objectives can be confusing, and detailed specs (or even basic properties) are often hard to find. Here's an introductory resource to help new builders and instrument designers with the basics. It's a work in progress so feedback is appreciated: amsikking.github.io/microscope_o...