Happy to share the first preprint out of the Nomburg lab! Many aspects of cellular immunity are shared across the tree of life. Here, we show that some of these conserved aspects of cellular immunity are mirrored by conserved effectors of immune antagonism. Thread below! 1/15

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · 2w ago

Conserved folds enable immune antagonism across the tree of life https://www.biorxiv.org/content/10.64898/2026.07.21.739742v1

RNA splicing was discovered in adenovirus almost 50 years ago. In our lab's first pre-print we have turned that relationship around, showing that viruses dependence on the cell's splicing machinery leads to a hidden vulnerability that can be targeted with drugs already in human clinical trials.

It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum.bsky.social demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats Apoorva Uboveja! www.nature.com/articles/s41...

αKG-mediated carnitine synthesis drives DNA repair via histone acetylation - Nature

The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications f...

nature.com

The wobble-skip mechanism of matching two-of-three bases is wildly cool. Most synonymous mutants can’t escape

Kenneth Loi@kenjmloi.bsky.social · 3mo ago

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

Our lab is hiring for a Research Assistant position! Please repost widely. jobs.dayforcehcm.com/en-US/wistar...

We are excited to share our new paper in Molecular Cell uncovering how the viral lncRNA RNA2.7 reshapes host cell biology! sciencedirect.com/science/authShare/S1097276526001565/20260324T143400Z/1?md5=16c84051c2f253c4665427f837a529d3&dgcid=author A thread 🧵

🚨 Postdoc position open - please repost! Join our lab in Lausanne🇨🇭to study KSHV, virus–host interactions & RNA decay + great quality of life right by Lake Leman and the Alps ⛰️ Apply here 👉 sites.google.com/view/muller-...

Muller Lab

Welcome to the Muller Lab website - here are our latest news:

sites.google.com

Have you ever wondered why children starting nursery/daycare pick up so many germs? I certainly did, and with a crack team of parent-scientists/clinicians, we set out to answer that question. Is childcare a germ factory or an immune bootcamp? journals.asm.org/doi/10.1128/...

Germ factories or immune boot camps? Infection and immunity in childcare settings | Clinical Microbiology Reviews

SUMMARYChildcare outside the home is a common experience for many children in high-income countries. It is associated with an increase in the incidence of infectious diseases—not just for the child bu...

journals.asm.org

Very excited to announce that the Price Lab has received a first major NIH award! In this five year NIGMS R35 MIRA we will be exploring fundamental processing and recognition of nuclear double-stranded (ds)RNA.

Very elegant microscopy and in depth interpretations!

Apratim (Appy) Mukherjee@mukherja.bsky.social · 11mo ago

(1/3) Excited to post our updated pre-print! We show RNAPII clusters are simply collections of polymerase molecules stably engaged at single genes & cluster intensity is strongly correlated with txn output during Drosophila embryogenesis. www.biorxiv.org/content/10.1...

Honored and grateful to be promoted to Professor. Thank you to the mentors, colleagues, students, and collaborators who made this possible.

The Wistar Institute@wistar.org · 7mo ago

Congrats to Dr. Italo Tempera on his promotion to Professor! After postdoc training in Wistar's Lieberman lab, he launched his own lab at Temple before returning to Wistar in 2020. Since then, he's published in top‑tier journals and had major grant success. 👏 Congrats! bit.ly/49mwnTv

Thrilled to share the first major preprint from the lab. Viruses are classically viewed as targets of host sensing. Do viruses also sense and respond to the host? We propose viruses may act as “biosensors” of the host signaling state. A thread👇🏾 www.biorxiv.org/content/10.1...

Global Landscape of Human Kinase Motifs in Viral Proteomes

Viruses are classically viewed as targets of host sensing, yet whether they also sense and respond to host cues remains largely unexplored. We propose that host-driven post-translational modification ...

biorxiv.org

Wonderful opportunity!

Lisa Akhtar@lisanakhtar.bsky.social · 8mo ago

The Akhtar Lab @manneresearch.bsky.social and Northwestern University @nufeinbergmed.bsky.social is hiring a full time RESEARCH TECHNICIAN. If you want to study neonatal HSV pathogenesis please send me a message and apply for the position here: luriechildrens.wd1.myworkdayjobs.com/externalport...

Well. It's certainly not boring over in vaccine world.

He made beer that’s also a vaccine. Now controversy is brewing

An NIH scientist’s maverick approach reveals legal, ethical, moral, scientific and social challenges to developing potentially life-saving vaccines.

sciencenews.org

🚨New faculty job opportunity 🚨 Please share this ad for a faculty position in our department at UC Irvine, in the fields of microbiology and infectious disease. MD/PhDs and PhDs are desired and should apply! recruit.ap.uci.edu/JPF09954

Pediatric Infectious Diseases/Microbiology - Professor Series (tenure track/tenure), Open Rank

University of California, Irvine is hiring. Apply now!

recruit.ap.uci.edu

🧬 Exciting news from our lab 🧬 The Swiss National Science Foundation (SNSF) has approved our project studying KSHV and RNA decay: our first grant since re-launching the lab in Switzerland 🎉 We’re now looking for a Postdoc and a PhD student to join the team (start date January 2026) - please repost!

I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com

Very excited to share the first publication from the Price Lab, "Replication-competent adenovirus reporters utilizing endogenous viral expression architecture", is now online at Journal of Virology! journals.asm.org/doi/10.1128/...

Replication-competent adenovirus reporters utilizing endogenous viral expression architecture | Journal of Virology

This research provides powerful new tools to rapidly study adenovirus gene expression and replication. By integrating fluorescent and secreted luciferase reporters into native viral regulatory element...

journals.asm.org

So excited to see our newest study out in print! Led by the brilliant @jgezelle.bsky.social and @sophiekorn.bsky.social, we discovered how viruses from highly divergent families converge on a shared RNA structure mechanism to inhibit cellular nucleases. #RNAsky #LoveVirology

Jeanine Gezelle@jgezelle.bsky.social · 11mo ago

Our study from the Steckelberg lab is out now in @narjournal.bsky.social !! We dove into a new nuclease-blocking viral #RNA structure important for viral infection, which provided evidence of similar structure-based strategies across diverse viral families. academic.oup.com/nar/article/...

First ever Price Lab paper accepted this morning!!! Hopefully follow-up post soon to showcase our new systems.

Stats: www.smbc-comics.com/comic/number... (also you can buy the mug and other smbc stuff here: smbc-store.myshopify.com/products/goo...) #smbc

The 20 years of sneezes to the face is what sent me, but every panel has a line that makes me laugh!

Zach Weinersmith@zachweinersmith.bsky.social · last yr.

Immune Full comic here: www.smbc-comics.com/comic/lesson #smbc

Excited to share that our latest story on Restrictor is out now in @genesdev.bsky.social!! Big thank you to my fellow co-first author Hanneke, Karen @adelmanlab.bsky.social and co-authors Nathalie and Allison!

Genes & Development@genesdev.bsky.social · last yr.

In this study, Mimoso et al. show that Restrictor serves as a transcriptional safeguard that suppresses the spurious transcription of non-coding RNAs, while preserving mRNA transcription. Learn more here: ➡️ tinyurl.com/gd352654

We are excited to share our recent work: EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation url: academic.oup.com/nar/article/...

EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation

Abstract. Epstein-Barr virus Nuclear Antigen Leader Protein (EBNA-LP) plays a pivotal role in the transformation of B cells by Epstein-Barr virus (EBV), fu

academic.oup.com

The Price Lab turned two years old this week! Of course we celebrated with cake, but the cherry on top was submitting our labs very first manuscript today! Excited to see what the rest of the year holds.

Postdoc positions available! Please re-post! Are you interested in how viruses manipulate chromatin? Are you excited to discover unknown facets of molecular biology? If so, we’d love to hear from you! Come check us out at: avgoustilab.org

Excited to share with you my postdoctoral work published today in Nature Microbiology! www.nature.com/articles/s41... We have known for a while that stress can impact the outcome of infectious diseases; however, we reveal in our paper that it is not always detrimental.

Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology

Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...

nature.com

#NewResearch 🚨Out now! Environmental stress drives clearance of a persistent enteric virus in mice 🐀 @christinviral.bsky.social @cadwelllab.bsky.social #MicroSky #VirusSky www.nature.com/articles/s41...

Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology

Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...

nature.com

#NoKings protest in Philadelphia