Rita Rebollo

@ritarebollo.bsky.social

just Rita

Next, Jesus Uxue Mendez Leyva on a recently acquired bacterial endosymbionts in weevils. Their genomes have lots mobile genomic elements suggesting that they are undergoing a period of genomic instability, and the genes associated with TEs might play a role in the symbiosis #EESSymbiosis

How do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...

Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells.

The Human Silencing Hub (HUSH) complex safeguards genome integrity in human somatic cells by repressing transposable elements and regulating type I interferon (IFN-I) induction. In early development, ...

biorxiv.org