Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...
Our new paper is out in @nature.com! We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females! A remarkable mammalian parallel to bees and ants! 🐝🐜 @garyrlewin.bsky.social youtu.be/enfv3zJrWKM?...
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
youtu.be
Horizontal gene transfer (HGT) in ants - several likely underpinning functional innovations, primarily by mediating immune-system adaptations or facilitating nutritional niche expansions academic.oup.com/gigascience/... #biodiversity #genomics
Comparative analysis of 163 ant genomes reveals recurrent horizontal gene transfer from bacteria to ants
AbstractBackground. Horizontal gene transfer (HGT) from bacteria can drive phenotypic innovation and adaptation in eukaryotes. Ants are likely carriers of
academic.oup.com
Yesterday, @nicolasparisot.bsky.social received his "Habilitation à Diriger des Recherches" in front of a jury composed of C. Braquart-Varnier, O. Duron, M. Sicard, T. Lefebure, and Z. Haichar. He brilliantly presented his research at @inrae-umr-bf2i.bsky.social. Congratulations 👏
Out today in Nature Microbiology: a paper that started in 2021 with an email from @sullivan-lab.bsky.social. Subject line: "Crazy ideas". www.nature.com/articles/s41... 1/23
Major development in the #Transposon world! Repbase is joining the Dfam project and becomes open-access! link.springer.com/article/10.1...
Unifying Repbase and Dfam: a new open foundation for transposable element research - Mobile DNA
Repbase and Dfam, the two foundational resources for transposable element annotation, are being unified into a single, fully open access framework, with Repbase released under CC-0 and its core curati...
link.springer.com
A New Open Foundation for TE Research: GIRI is transitioning the full Repbase collection to an open-access license and joining the Dfam effort to help build a unified open resource for transposable element research. Full announcement: tinyurl.com/48665xss
Yes!!!!
A New Open Foundation for TE Research: GIRI is transitioning the full Repbase collection to an open-access license and joining the Dfam effort to help build a unified open resource for transposable element research. Full announcement: tinyurl.com/48665xss
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
Host-transposable element coexistence: a matter of resistance, tolerance and trade-off Read this new review by Séverine Chambeyron, Charlotte Grimaud, Mikiko Siomi et al link.springer.com/article/10.1...
🧬 Interested in Transposable Elements? Join our course with @valentinapeona.bsky.social @ritarebollo.bsky.social @clementgoubert.bsky.social & learn about TE libraries, genome annotation, insertion polymorphism, transcriptomics, manual curation and much more www.physalia-courses.org/courses-work...
Our latest publication is now out at Genome Biology! link.springer.com/article/10.1... We uncover a unique association between a H3K27me3 reader complex and active transcription. A thread with our key findings: (1/8) #TEsky #Polycomb #transcription #smallRNAs
A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology
Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...
link.springer.com
This week @annazaidmanremy.bsky.social and @jesuxueml.bsky.social were at the EMBL symposium entitled “The cellular mechanics of symbiosis: sensing friend from foe” @events.embl.org. They gave excellent presentations which sparked lively discussions! #EESSymbiosis #SymbioSky
Next, Jesus Uxue Mendez Leyva on a recently acquired bacterial endosymbionts in weevils. Their genomes have lots mobile genomic elements suggesting that they are undergoing a period of genomic instability, and the genes associated with TEs might play a role in the symbiosis #EESSymbiosis
Following the #EESSymbiosis @events.embl.org through Bluesky! Keep posting! @annazaidmanremy.bsky.social gave a wonderful talk yesterday (I've been told!), & @jesuxueml.bsky.social will take the floor today! Have fun, I'm not jealous at all #FOMO And go Mobile Genetic Elements <3 #SymbioSky
We are looking for a Postdoc to join our lab at @oxfordbiochemistry.bsky.social. This is a dry-lab focused post on the computational analysis of long read single-cell sequencing data to understand the role of transposable elements (TEs) in early development. my.corehr.com/pls/uoxrecru... #TEsky
This link will take you to a page that’s not on LinkedIn
lnkd.in
🚨📢📄 Article in press in Genome Biology doi.org/10.1186/s130... We introduce panREPET, a reference-free pipeline to detect shared transposable element (TE) insertions across pangenomes and retrace their evolutionary dynamics #TEsky 🧵👇
A reference-free pipeline for detecting shared transposable elements from pan-genomes to retrace their dynamics in a species - Genome Biology
Background The role of transposable elements (TEs) in host adaptation has gained interest in recent years. Individuals of the same species undergo independent TE insertions, providing genetic variabil...
doi.org
Everything you always wanted to know about TE classification ! @nico971.bsky.social and @johannconfais.bsky.social present RepetDB a TE database to support your science at GDR #MobilET meeting.
Time to publish responsibly: DAFNEE, a database of academia-friendly journals in ecology and evolutionary biology url: academic.oup.com/jeb/article/...
Time to publish responsibly: DAFNEE, a database of academia-friendly journals in ecology and evolutionary biology
Abstract. The current economics of scientific publishing reveal a profound imbalance: academia pays prices far exceeding the actual costs of publication. R
academic.oup.com
Hi! Florence Hommais, @nicolasparisot.bsky.social , and I are looking for a postdoctoral candidate to investigate the molecular dialogue between three weevil species and their endosymbiotic bacteria #symbiosis! Please see the #post-doc offer for more information. #SymbioSky #Bioinformatics
Had to draw a cartoon for this fascinating finding! Defensive fungal symbiosis on insect hindlegs: www.science.org/doi/10.1126/... #SymbioSky
How do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...
Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells.
The Human Silencing Hub (HUSH) complex safeguards genome integrity in human somatic cells by repressing transposable elements and regulating type I interferon (IFN-I) induction. In early development, ...
biorxiv.org
Internship position open at INRAE-URGI for 2026, more details available here www.sfbi.fr/emplois/offr...
Optimisation de la classification automatique des éléments transposables par des approches d’IA | SFBI Société Française de Bioinformatique
Emploi en bioinformatique à None Stage Stage M2
sfbi.fr
📣 #OurLastPaper is out! And it's a major breakthrough that we're publishing in @cp-cell.bsky.social l: we've discovered architect bacteria that build complex structures to feed themselves better! #SymbioSky 1/5
1/9 New in @science.org www.science.org/doi/10.1126/science.ado8005 How does genetic architecture constrain evolutionary trajectories? To address this question, we inferred the genetic architecture of convergent plumage coloration and its evolutionary history in wheatears.
A mosaic of modular variation at a single gene underpins convergent plumage coloration
The reshuffling of genomic variation from multiple origins is an important contributor to phenotypic diversification, yet insights into the evolutionary trajectories of this combinatorial process and ...
science.org
🚀 The next edition of Bioinformatics of Transposable Elements with @valentinapeona.bsky.social & @ritarebollo.bsky.social is just around the corner! 🧬 Jump into the world of #transposons and level up your #bioinformatics skills ⏳ Seats are limited: www.physalia-courses.org/courses-work...
🧑🔬 The fête de la science Symbiosis walk was a success! Thank you all the school and families that have shared a bit of their curiosity with us 🪲🦠
Come talk Symbiosis with me! 😍
📅 On October 10–11, members of @inrae-umr-bf2i.bsky.social & MAP will guide you through the alleys of La Doua Campus to talk all about symbiosis! ✨ Book your slot here 👉 www.fetedelascience.fr/la-symbiose-... 🎉 Join us for a fun time at Fête de la Science!
Dear all, registration for the upcoming EMBO/EMBL Symposium on "the cellular mechanics of symbiosis" is now OPEN 🤩 ! Feel free to register ! www.embl.org/about/info/c... #EESSymbiosis #ProtistsOnSky #SymbioSky @hassansalem.bsky.social @berasymbionts.bsky.social @embl.org
The cellular mechanics of symbiosis: sensing friend from foe
embl.org