“Reform has the most extreme policy on energy and climate the UK has seen since modern science on the subject began. The party opposes solar; it opposes wind; it opposes batteries… Once again: Reform is largely funded by fossil fuels” Private Eye on the anti-thought, pro-corruption threat of Reform
Teddy Tun Win HLA
@teddyhla.bsky.social
- intensive care medicine specialist registrar in London with an interest in cardio respiratory failure #ECMO - data scientist in health sector [own views / not related to employer]
@jama.com hi I can’t seem to access supplementary material of this paper. It just didn’t load. Other colleagues with right access tried unsuccessfully too. Can you have a look? Thanks jamanetwork.com/journals/jam...
Levosimendan to Facilitate Weaning From ECMO in Patients With Severe Cardiogenic Shock: Research Summary
This study aimed to determine if early levosimendan administration shortens the time to successful weaning from venoarterial extracorporeal membrane oxygenation (VA-ECMO) in adult patients with severe...
jamanetwork.com
A point of view. Thought you might like this. @doced.bsky.social kancelaria-skarbiec.pl/en/the-death...
The Lucy Letby Case: Presumption of Innocence vs Statistics
The Letby case illustrates a broader truth about human cognition: we're pattern-seeking creatures in a world where true randomness often looks like pattern.
kancelaria-skarbiec.pl
www.weightmans.com/media-centre... This ruling is just a lot to unpack. 😨
Clinicians or Court: Who decides about medical treatment options? Exploring the case of Townsend v Epsom
The Court of Appeal decision of Townsend v Epsom would change medical law fundamentally, but we should not overreact pending any appeal...
weightmans.com
@ficm.bsky.social is here on Bluesky. 👏🏽👏🏽👏🏽Give a follow iCM people ! :)
Proud to be part of this ! Excellent work from the team. www.kcl.ac.uk/news/securin...
Securing patient data in large-scale AI healthcare development: AI Centre and deepc launch FLIP | King's College London
The AI Centre for Value-Based Healthcare, King’s College London, and Guy’s and St Thomas’ NHS Foundation Trust, together with strategic partner deepc, in collaboration with OneLondon and Flower Labs, ...
kcl.ac.uk
Very sadly Seshagiri Mallampati, the anesthesiologist who devised the Mallampati score, die two weeks ago. He only retired in 2017, 49 years after he began clinical practice. litfl.com/seshagiri-ra...
Seshagiri Rao Mallampati
Seshagiri Rao Mallampati (1941 – ) Indian born American anesthesiologist. Eponym: Mallampati Score used to predict the ease of endotracheal intubation
litfl.com
This is basically my villain origin story. "How old are you?" (unique responses)
OpenSAFELY is open from today! Huge thanks to all who supported this vast collaboration: whole population GP data; in a productive platform; innovative privacy protections; unprecedented support from professions, privacy campaigners; &c Now it's over to users! www.bennett.ox.ac.uk/blog/2026/02...
OpenSAFELY news: you can apply to do non-COVID research, from today! | Bennett Institute for Applied Data Science
We are delighted to announce that - from today - you can submit applications to the OpenSAFELY service for non-COVID-19 studies.
bennett.ox.ac.uk
Proud to have graduated at this venue @ficm.bsky.social and didn’t realise its history ! youtube.com/shorts/VqtA9...
What incredibly historic meeting took place in Methodist Central Hall 80 years ago?
YouTube video by Jack Chesher- Living London History
youtube.com
🎥 Maximizing donor pool: #ECMO driven advances in #transplantation: ELSO & @ishlt.bsky.social #ELSO2025 session 🧠 diagnosing BD in #ECLS 🚑 #ECPR to organ donation ⚙️ #NRP and MP in cardiothoracic #Tx ⚖️ ethical dilemmas of #ECLS, DCD, NRP 🫁🫀 DCD for pediatric recipients 🔗 bit.ly/ELSO2025virtual
@kamranabbasi.bsky.social shines with this scathing editorial on the mess that has been made with locally employed Doctors (LEDs) in the U.K. www.bmj.com/content/391/...
NHS 2025: a wobbly triadic stool and a gig economy
The NHS sits seventh on the list of the world’s largest employers, rubbing shoulders with the armies of China, India, and the US, as well as mega-corporations.1 It’s also part of the “gig economy.” Th...
bmj.com
Firstly, do no (net) harm. ~ (adapted from) Hippocrates Reading Hunink et al (2014) this morning…
🧐
Fascinating paper suggesting the assumption that there is a sigmoid dose response relationship and threshold effect ( "all-or-nothing") for loop diuretics rests on repeated misinterpretation of original studies from the 70s and 80s. #nephsky #cardiosky #emimcc academic.oup.com/ehjcvp/artic...
So a recent Veritasium video on natural selection explains kin selection and does the unavoidable thing of saying that a parent shares "half of its genes with the child". This is wrong, because for any 2 humans, we share almost all of our genes. We share more than 95% with chimpanzees ffs. >>
This honestly should be required reading for anyone undertaking (or evaluating) exploratory studies... ⬇️👍 (It's proper funny too 😅)
Which reminds me of this old classic on the Noise Miners. “'Noise mining is a funny thing,' he said. 'When you first see a bit of noise, it doesn’t look so impressive. But as you work it out of the rock, it gets more and more refined.' This process, he explained, is called 'shucking.'"
NEW paper "Clinical prediction models using machine learning in oncology: challenges and recommendations" --> tinyurl.com/2h2mcy5h #machinelearning #prediction #statssky #MLsky #methodsmatter
Which reminds me of this old classic on the Noise Miners. “'Noise mining is a funny thing,' he said. 'When you first see a bit of noise, it doesn’t look so impressive. But as you work it out of the rock, it gets more and more refined.' This process, he explained, is called 'shucking.'"
The Noise Miners
As regulators turn an eye toward noise mining, I wanted to meet some of those who will be affected
medium.com
Pergaminium is what you go dig for in the paper mines.
Remembering the most likely mediator of reduced mortality in the original EGDT therapy was the presence of the CI in the intervention arm, the regular attendance of an interested and informed clinician (and skilled ICU nurse) likely has a bigger impact than any single drug or intervention.
"One intangible advantage of capillary refill time is that performing it brings the clinician back to the bedside to reassess the patient. This act may be itself the holy grail of early sepsis management." great piece on #sepsis
💬 Editorial: The BICARICU-2 trial finds IV sodium bicarbonate may delay or reduce kidney replacement therapy in #criticallyill patients with severe #acidemia and #AKI, but its effect on mortality remains uncertain. #LIVES2025 @esicm.bsky.social ja.ma/47NwK8E
ANDROMEDA-SHOCK-2 is up next…. this looks at personalised phenotype-based, capillary refill time (CRT) targeted resuscitation in early septic shock, comparing to standard resuscitation. It is large (86 centres, 19 countries). Read it free from JAMA: tinyurl.com/mjcj8s5w #Lives2025 #criticalcare
Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock
This randomized clinical trial examines whether a personalized hemodynamic resuscitation protocol targeting capillary refill time was more effective than usual care in patients with early septic shock...
tinyurl.com
EVERDAC is hot off press @esicm.bsky.social #Lives2025 in @nejm.org open access currently: www.nejm.org/doi/full/10.... Reports that in (non-blinded trial) patients with shock, management *without* early a-line insertion was noninferior to early catheter insertion…. #Lives2025 #criticalcare
Deferring Arterial Catheterization in Critically Ill Patients with Shock | NEJM
In patients with shock, whether noninvasive blood-pressure monitoring is an effective alternative to the recommended use of an arterial catheter is uncertain. In this multicenter, open-label, nonin...
nejm.org
In light of the art line trial. Interesting result. Need to read in depth. We really have gone full circle. A lot reflects on my practice and how I have grown up doing icu 2016 on wards and the UK practice. Back in those days, icu is a place where things are done “properly” @drfreeze.bsky.social 1/n
well, gonna have to read this
📚 Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score: Presented today in the #LIVES2025 Hot Topics session. 🔗 Free to read online: ja.ma/4qzouAz
From @jamanetworkopen.com: The SOFA-2 score updates the 1996 Sequential Organ Failure Assessment, reflecting current definitions, variables, and thresholds to grade organ dysfunction in critically ill adults receiving intensive care. #LIVES2025 @esicm.bsky.social ja.ma/3JuguA7
Who’s watching
Trials coming up at #esicm #lives2025 I am by far most interested in #andromedashock2. The usual yearly sweepstakes apply ping @avkwong.bsky.social @redneeraj.bsky.social I think all of those trials will be “positive”. Your thoughts?
We now have a stream of garbage in US newspapers, like this one in @washingtonpost.com denigrating London, all coded attacks on @zohrankmamdani.bsky.social Well, I live in London, love it, and am delighted to have Sadiq Khan @london.gov.uk as my mayor. www.washingtonpost.com/opinions/202...
Opinion | London’s sad decline is a warning to New Yorkers
In three terms as mayor, Sadiq Khan has crushed the economic life out of Britain’s capital.
washingtonpost.com