Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...
Theresia Gutmann
@thegutmann.bsky.social
European Molecular Biology Laboratory (EMBL) Membrane Biology • Receptor Proteins • Signal Transduction • Immunity ORCID: 0000-0003-0562-2880 Google Scholar Profile: https://scholar.google.de/citations?user=ZfCAngoAAAAJ&hl=en
Nachgefragt: Dr. Theresia Gutmann im Interview www.biospektrum.de/artikel/nach... @thegutmann.bsky.social Copyright rechter Bildteil: Katrin Boes (MPI-CBG)
The need for strong #ScientificSocieties has taken on a new urgency in the era of AI. It was a pleasure and an honor to deliver the #keynote lecture at the Polish Biochemical Society symposium on "New Perspectives in Biochemistry Research" at the Wrocław University of Science and Technology.
Can a German scientist make science fun and understandable? I will be giving a #ScienceSlam at the Grand Finale of the Long Night of Sciences. Join me for the "Mission Invisible! Virale Tricks gegen das Immunsystem" at TU Dresden. @tudresden.bsky.social @mpi-cbg.de #Immunology #Virology #SciComm
Had a fantastic EMBO|EMBL Symposium on "Cellular Mechanisms Driven by Phase Separation" and was delighted to present our perspective on biomolecular condensation in virus–host interactions. Congrats to our Predoc Silja Zedlitz @hymanlab.bsky.social on her poster prize! #2026PhaseSeparation @embl.org
As part of @sfb1638.bsky.social in 𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞 𝐑𝐞𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠, we are committed to developing computational tools that make complex membrane simulations more accessible, reproducible, and scalable for the scientific community. Today, we are happy to share the public release of 𝐎𝐩𝐞𝐧𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐁𝐮𝐢𝐥𝐝𝐞𝐫 v1.2.1
Safe to say that Day 1 of 'Cellular mechanisms driven by phase separation' has been a success so far, with lots of great talks, including a keynote by Karla Neugebauer, and plenty of opportunities to socialise and get to know each other 🙌🏼 #EESPhaseSeparation @embo.org @embl.org
Did you know that most of our conferences are in a hybrid format? Even if you are unable to travel, you have a few more days to register to attend #EESPhaseSeparation virtually! 🧬🦠🧪 • Access talks at your convenience • Ask questions • Network Register by 12 May: s.embl.org/ees26-08-bl
This is the most detailed 3D rendering of a eukaryotic cell to date, obtained using X-ray, nuclear magnetic resonance (NMR), and cryo-electron microscopy datasets. 🔬🧪
Anthony Hyman @embl.org & @mpi-cbg.de @hymanlab.bsky.social & Clifford Brangwynne @princetonupress.bsky.social & @hhmi-science.bsky.social receive their 2023 Breakthrough Prize at the Awards Ceremony in Santa Monica,LA, April 18, by Eileen Gu & @mrgatoasdf.bsky.social! www.mpi-cbg.de/news-outreac...
Breakthrough Prize Award Ceremony
Antony Hyman and Clifford Brangwynne receive their 2023 Breakthrough Prize
mpi-cbg.de
Cells are not just bags of molecules. Function depends on spatial interactions: RNAs and/or proteins come together with interaction partners to drive regulation and function. In our new preprint, we introduce ProPER, a novel method for in situ proximity detection. Preprint: tinyurl.com/muju86s6
1/ ProPER - Our novel ligation-free proximity detection method for efficient multiplexed imaging of molecular interactions in situ. Among other things we use it to image the life cycle of RNA molecules and resolve differential kinetics of gene expression steps. New preprint: doi.org/10.64898/202...
Heartfelt congratulations to our new PhD student Silja Zedlitz on receiving the Rainer Rudolph Award 2025 for her MSc thesis in the lab of @kjohnsson.bsky.social on minimal rhodamine probes for protein labeling in cells. @hymanlab.bsky.social @mpi-cbg.de @gbmev.bsky.social @mpi-mr.bsky.social
Our work is finally out in Science Immunology ! This was an Amazing collaborative work from all co-authors, in particular the two co-first authors James Curson and Syeda Farhana Afroz . Never give up ! :) www.science.org/doi/10.1126/...
Mitochondrial fission mediates an evolutionarily conserved antibacterial defense response
Mitochondrial fission promotes antibacterial defense via the mitochondrial unfolded protein response and inducible lipid droplets.
science.org
Excited to share our paper on the NLRP3 inflammasome condensate at the Microtubule Organizing Center (MTOC) by "precise!" cryo-electron tomography (cryo-ET), in collaboration with Jue (phyllis) Wang in the labs of Grant Jensen (BYU) and Pete Dahlberg (Stanford)! www.science.org/doi/10.1126/...
Design principles of human membrane protein topology https://www.biorxiv.org/content/10.64898/2026.04.18.719382v1
Dear Lipid and Membrane Enthusiasts, There is only one month!! left to register and submit your abstracts for the @embo.org Workshop “Lipid Code to Life”, which will be held from September 7–11, 2026, in Dresden, Germany. Workshop program and registration page: meetings.embo.org/event/26-lip...
Lipid Code to Life
Modern lipid biology has evolved far beyond the traditional view of lipids as simple building blocks or energy substrates. Lipids are now recognised as dynamic regulators of biological structures and…
meetings.embo.org
www.nature.com/articles/s41...
SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis - Nature Cell Biology
Liu, Gad et al. develop an approach to purify the endoplasmic reticulum and integrate genetic, structural, molecular and cell biological analyses to identify SLC33A1 as an endoplasmic reticulum oxidiz...
nature.com
Lipid-CLEM by @mathilda95.bsky.social on the Cover of @natcellbio.nature.com! Link to article: www.nature.com/articles/s41...
A renaissance in targeting the PI3K/AKT/mTOR pathway www.nature.com/articles/s41... rdcu.be/faYxr This new Perspective discusses how advances in understanding of PI3K signalling in disease and novel pharmacological strategies are revitalizing interest in targeting the pathway
Welcome, Tony Hyman! EMBL welcomes its new Director General, Tony Hyman, as he takes up the mandate of leading EMBL's six sites. www.embl.org/news/embl-an...
Have you registered yet? Early bird registration and abstract submission are open until January 31. mosbacher-kolloquium.org
Ein internationales Forschungsteam unter der Leitung von Prof. Dr. Konstanze F. Winklhofer, @ruhr-uni-bochum.de, hat einen entscheidenden Mechanismus der zellulären Müllabfuhr entschlüsselt. advanced.onlinelibrary.wiley.com/doi/10.1002/... Bild: Erstautorin Georgina Herrera, © RUB, Marquard
Ups we did it again! Please mark your calender. EMBO Workshop “Lipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova, @lipid.bsky.social, Valerie O'Donnell, @holthuislab.bsky.social and @molcellbiophys-lab.bsky.social 🥳 Retweets = lipidlove
Congratulations to Julia Mahamid @embl.org on receiving the #LeibnizPrize 2026 for her pioneering work in in situ #structural #biology and for advancing our understanding of molecular architecture and cellular dynamics.
Und hier sind sie – die 10 Preisträger*innen des Gottfried Wilhelm #LeibnizPreis' 2026 – ausgezeichnet für ihre exzellenten Forschungsarbeiten und Errungenschaften in der Wissenschaft! 🏆👏 Die Verleihung der Preise feiern wir am 18. März in Berlin. Einzelheiten & Kurzprofile: sohub.io/1uv1
Here is a short video by @tudresden.bsky.social (in German) of me explaining what beta cells do and talking about our research on investigating the structural features of their function and dysfunction.
Wie wird #Insulin produziert? Was passiert bei #Diabetes im Körper? 🩸 In der »Kurzen Frage« spricht @andimicroscopy.bsky.social vom Paul Langerhans Institut von @helmholtzmunich.bsky.social & #TUDresden über seine Forschung an den Betazellen der Bauchspeicheldrüse. Zum Video ➡️ youtu.be/KAeSulc4Neo
𝐂𝐨𝐧𝐠𝐫𝐚𝐭𝐮𝐥𝐚𝐭𝐢𝐨𝐧𝐬 𝐨𝐧 𝐫𝐞𝐜𝐞𝐢𝐯𝐢𝐧𝐠 𝐭𝐡𝐞 𝐒𝐓𝐒 𝐒𝐜𝐢𝐞𝐧𝐜𝐞 𝐀𝐰𝐚𝐫𝐝 2025! 🎉 At the 28th STS Meeting in Weimar Theresia Gutmann @thegutmann.bsky.social was honored with this award, which recognizes outstanding research by postdocs or junior PIs within the STS. Congratulations! @mpi-cbg.de #STS #CellCommSummit
Tony will become the next EMBL Director General! Congratulations, @hymanlab.bsky.social, exciting times ahead!
Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...
🎉 Hao Wu received the STS Honorary Medal for her lifetime contributions to uncovering molecular details of innate immune signaling. The laudatio by Theresia Gutmann highlighted her impact as scientist and mentor. Prof. Wu: your brilliance, dedication, and humor made this evening unforgettable ! 🌟
We had a good line up of speakers at the 50 years anniversary meeting of the german society of cell biology @dgz.bsky.social in Heidelberg. Tony gave the plenary, Koichiro talked about spatial control of P granules and Silja received a price for her Master thesis and gave a talk. Congratulations!