I am deeply moved and grateful to receive the Sue Eccles award from the @metastasisresearch.bsky.social, a community whose work I admire profoundly. It really belongs to my mentors; they are the ones that helped me reach this point! So this is to you @megeblad.bsky.social and @drusqui.bsky.social

Thrilled to welcome the wonderful @adrover.bsky.social to Zurich for our monthly SMyLe @smyle-ch.bsky.social seminar! 📅 March 24 | 16:30 📍 ETH Hönggerberg Join us to hear José present his great science! Special thanks to @syis-ecr.bsky.social for supporting this event!

Swiss Myeloid League (SMyLe)@smyle-ch.bsky.social · 5mo ago

The next SMyLe seminar is coming up soon! Please join us on March 24th at 16.30 at ETH Höngg (HCI J6) or via Zoom (ethz.zoom.us/j/63706799264) for a talk by @adrover.bsky.social "From Guardians to Foes: Cancer-induced host remodelling and neutrophil plasticity drive tumour necrosis and metastasis"

Are you a clinician looking for a fully-funded postdoctoral research opportunity? Check out our postdoctoral career development fellowships for clinicians, and see how you can join our vibrant community: www.crick.ac.uk/careers-and-...

Postdoctoral clinical fellows

Opportunities for postdoctoral clinicians to consolidate their research experience.

crick.ac.uk

Absolutely delighted that our latest paper is out today @natimmunol.nature.com. It has taken five years to uncover a role for cross-presentation in shaping the immune visibility of tumour antigens. A labour of love led by @drjonlim.bsky.social and Oliver Schulz. Great start of 2026!

The Francis Crick Institute@crick.ac.uk · 7mo ago

Researchers at the Crick have uncovered how certain proteins that become exposed on dying tumour cells can be detected by the immune system, alerting it to the cancer’s presence and prompting an immune response. www.crick.ac.uk/news/2025-12...

🏆 MRS Sue Eccles Early Career Investigator Award: Jose M. Adrover

🚀 Two weeks to go! The ECR Meeting brings together early-career scientists driving the next wave of metastasis research. ⚡ Don’t miss: 💡 Inspiring talks from rising leaders 💬 Community-led discussions 🌍 A global metastasis community 🗓️ Register by Nov 18 ➜ bit.ly/4qyxE0o Program ➜ bit.ly/4qtpVR9

2nd MRS Early Career Research Virtual Meeting | Metastasis Research

The 2025 MRS Early Career Research Virtual Meeting is a two day meeting aimed at engaging trainees and early career researchers from around the world and highlighting recent advances in metastasis research through keynote presentations, invited talks, panel discussions, and selected talks from abstracts. The meeting is organized and hosted by the Early Career Leadership Council (ECLC) of the MRS. Abstracts are being accepted for consideration for oral presentations. Abstract submission is open to graduate students, postdoctoral fellows, medical students, residents, clinical fellows, and researchers within 3 years of starting their own independent research group. Registration for this meeting is free for MRS Members!

metastasis-research.org

This review from Ambreen, @adrover.bsky.social et al. explores cancer-elicited changes to #neutrophil behaviour and proposes ways in which these may contribute to cardiovascular pathology. rupress.org/jem/article/... 📘 In #Cytokines collection: rupress.org/jem/collecti... #Cytokines2025

My lab will be recruiting a PhD student this year. Have a look and apply if it sounds interesting! adroverlab.com/open-call-fo...

Open call for a PhD student - Cancer Macroenvironment Lab

Investigating the role of neutrophils in tumour progression, microenvironment dynamics and metastatic spread Application deadline: 5th of November, 2025 Project background and description Our laborato...

adroverlab.com

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

🔥Trio Fatale: Neutrophils, NETs and Necrosis 👉 authors.elsevier.com/a/1lk-k3qNrU... We summarized for @cp-immunity.bsky.social "Neutrophils drive vascular occlusion, tumour necrosis and metastasis" published in @nature.com by @megeblad.bsky.social @adrover.bsky.social rdcu.be/eFdau Congrats!

A new model of #TumorNecrosis👹 Tumor CXCL1➡️myeloid skewing➡️ Ly6C-low Neutrophil forms intravascular #NeutrophilExtracellularTrap➡️ Intratumoral vascular occlusion➡️ Pleomorphic Necrosis-to-Metastasis a role of TGFβ @adrover.bsky.social @megeblad.bsky.social Nature 2025 www.nature.com/articles/s41...

Heart of the matter: #Neutrophils, #cancer, and #CardiovascularDisease. New review from Saira Ambreen, Afshan McCarthy, Andrés Hidalgo, and Jose Adrover @adrover.bsky.social @crick.ac.uk: rupress.org/jem/article/... #TumorImmunology #CardiovascularBiology #InnateImmunity #inflammation

#Cancer patients display an elevated burden of #CardiovascularDisease. This review from Ambreen, @adrover.bsky.social et al. explores cancer-elicited changes to #neutrophil behaviour and proposes ways in which these may contribute to cardiovascular pathology. rupress.org/jem/article/...

Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neutrophils, cancer, and cardiovascular disease", just published @jem.org with Saira Ambreen, Afshan McCarthy and @drusqui.bsky.social rupress.org/jem/article/...

Thanks to Cancer Discovery for highlighting our manuscript with such a nice summary! Intravascular Neutrophil-Derived NETs Drive Tumor Necrosis and Metastasis aacrjournals.org/cdnews/news/...

Intravascular Neutrophil-Derived NETs Drive Tumor Necrosis and Metastasis

Major Finding: A Ly6GhighLy6Clow subset of neutrophils drives pleomorphic necrosis by forming intravascular neutrophil extracellular traps (NET).Concept: Tumor cells adjacent to neutrophil-induced nec...

aacrjournals.org

@cdi-einstein.bsky.social Director @jaguirreghisolab.bsky.social co-leads a study showing how viral infections can trigger via IL6 signaling awakening of dormant breast cancer cells in lungs. CDI's research focuses in part on host variations controlling the timing of residual cancer awakening

Aguirre-Ghiso Lab@jaguirreghisolab.bsky.social · last yr.

Delighted to see this story out and collaborate with amazing teams led by @jdegregori.bsky.social Mercedes Rincon & @roelvermeulen.bsky.social. Proud to see science propelled by our lab @cdi-einstein.bsky.social expanded to better understand cancer dormancy. Congrats! www.nature.com/articles/s41...

Nature research paper: Neutrophils drive vascular occlusion, tumour necrosis and metastasis go.nature.com/4lzilSb

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature

Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

go.nature.com

Happy to share our latest preprint doing low cell number (mini-bulk) and single cell #proteomics on tumour associated neutrophils from human glioblastoma where we find multiple functional states that would be invisible to scRNAseq, some showing pro-tumoural states with potential therapeutic value

Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma

Neutrophils are vital innate immune cells shown to infiltrate glioblastomas, however we currently lack the molecular understanding of their functional states within the tumour niche. Neutrophils are k...

biorxiv.org

A fascinating study reports that neutrophils and NETs actively induce tumor necrosis. Congratulations, BDP @megeblad.bsky.social and @adrover.bsky.social on your latest publication in @nature.com.

Mikala Egeblad@megeblad.bsky.social · last yr.

As a new postdoc in my lab (@cshlnews.bsky.social → @jhu.edu) @adrover.bsky.social (now @crick.ac.uk) saw NETs in tumors—I shrugged. But he looked closer in 3D: NETs block tumor vessels, driving necrosis, hypoxia, EMT & metastasis. 🔗 www.nature.com/articles/s41... @jhu-bdps.bsky.social @nature.com

As a new postdoc in my lab (@cshlnews.bsky.social → @jhu.edu) @adrover.bsky.social (now @crick.ac.uk) saw NETs in tumors—I shrugged. But he looked closer in 3D: NETs block tumor vessels, driving necrosis, hypoxia, EMT & metastasis. 🔗 www.nature.com/articles/s41... @jhu-bdps.bsky.social @nature.com

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature

Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

nature.com

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13) www.nature.com/articles/s41...

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature

Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

nature.com

Are you curious about how cancer impacts immune cell progenitors and how that changes mature cell function? My lab will soon be recruiting a Postdoctoral Fellow. If you are interested, please find more information here: adroverlab.com/open-positio...

Open call for a Postdoctoral Fellow - Cancer Macroenvironment Lab

Open postdoctoral position at the Cancer Macroenvironment Lab led by Dr. Adrover at the Francis Crick Institute in London

adroverlab.com

💥 Really excited to say that our paper with Karin de Visser and @dewitlab.bsky.social is now online! A beautiful story to culminate years of great collaboration and teamwork at the @nkinl.bsky.social. A 🧵 www.sciencedirect.com/science/arti...

Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

Tumor-induced systemic accumulation and polarization of neutrophils to an immunosuppressive phenotype is a potent driver of metastasis formation. Yet,…

sciencedirect.com

I had a wonderful time in the Tumor Microenvironment Working Group session! #AACR25 Thanks everyone for the warm welcome and lively discussion!

William Hill is presenting his work on air pollutants in lung adenocarcinoma in a fascinating session exploring ageing and environmental factors in the development and spread of lung cancer. #AACR25 | @drwilliamhill.bsky.social | @crick.ac.uk

If you’re attending #AACR25 stop by and say "Hi!" to our colleagues in @cancergrand.bsky.social at stand 2327, and Cancer Tools at stand 2424 in the exhibition hall.

I’m thrilled to be presenting our work next Monday the 28th at the #AACR25 in beautiful Chicago!

OBS #Immunology Seminar Neutrophils and regulation of skin physiology 📆 Thu, 10th April, 12 pm EDT/5 pm CET 🎙️ Speaker @alazozcan.bsky.social @yalesph.bsky.social @drusqui.bsky.social @cnic @nature.com 📣 Moderator @eugecc.bsky.social us02web.zoom.us/meeting/regi...

I had a wonderful time! Great conference and speakers! Thanks @casanova-acebes.bsky.social @sancholab.bsky.social and Carlos Silvestre for the great work organizing such an amazing meeting!

Casanova-Acebes Lab@casanova-acebes.bsky.social · last yr.

@adrover.bsky.social rocking on a fantastic new and vascular-damaging Ly6Clo neutrophils, he will now investigate deeper in his #brandnewlab #EPW2025

Last contribution to the understanding of #neutrophil biology. Superb work from Tommaso, @alazozcan.bsky.social, and Jackson that I had the pleasure to contribute to and see growing during my time at @drusqui.bsky.social lab.

Andres Hidalgo@drusqui.bsky.social · last yr.

Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork! Free link: rdcu.be/eeeA2 www.nature.com/articles/s41...