It was my pleasure to attend the workshop which was a full day of amazing science!

Center for Advanced Studies@caslmu.bsky.social · last wk.

A great kick-off for our new #CASesearchFocus "Nucleic Acid Stress" with the workshop "Nucleic Acid Stress and Surveillance." Exciting discussions and a fantastic start with participants including Tuğçe Aktaş @aktast.bsky.social @molgen.mpg.de, Daphne Selvaggia Cabianca @helmholtzmunich.bsky.social

Today, it was Lisa's turn to defend her PhD thesis and she did an absolutely fantastic job 😍 Especially going into full structure of the RNA Pol2 catalytic core and explaining the mutants. It was an outstanding discussion! I am really proud of her performance today 🥹

Tomorrow I'll be at @molgen.mpg.de, hosted by @aktast.bsky.social and @glazar.bsky.social. I come to Berlin all the time and I've never visited! Tomorrow, we fix that😊 I'll meet w/ PIs to discuss their work, and I'll also give a talk about life as an editor. If you're around, please come say hi!

It was my pleasure to present our work and attend career event at the 7th national molecular biology and genetics meeting organized by the students of Iztech. The future of Turkish molecular biology community is bright 🤩

👋 Transposon lovers: registration is now open for the CSHL TE meeting! We have a 🔥 lineup of invited speakers and many slots for short talks selected upon abstract across all areas of TE biology. 🧬➰🧬 #TEsky Abstract deadline: July 10 meetings.cshl.edu/meetings.asp...

In our "Meet the first author" series we spoke with Lisa Martina and Michal Malszycki about their recent paper, their fascination with nuclear speckles, and how an unexpected discovery helped them gain insight into the functions of speckles. www.molgen.mpg.de/news-2026-mt... @aktast.bsky.social

Our super star MSc student Sarah just passed her defense with flying colors (sehr gut, 1.0). I'm proud of you Sarah 🤩

The research highlight of our recent work on nuclear speckles is online. The photo choice is eggcellent. Happy Easter! 🌸🐰🥚 www.nature.com/articles/s41...

Nuclear speckles of GC richness - Nature Reviews Molecular Cell Biology

Nuclear speckles support the splicing of levelled exon–intron architecture transcripts, and their evolution shaped genome organization in amniotes.

nature.com

Proud PI moment with @malszycki.bsky.social today. Michal got his paper out last week, defended the thesis today and will be starting his postdoc in 2 weeks🔥

Our Lab is searching a postdoc for an exciting ERC-funded project that will start this summer. Apply if you’re passionate about multi-omics, cutting-edge computational approaches, and exploring biological questions across the animal 🪼 🪱 🐞 🦎 🦋 🕷️ tree of life www.biozentrum.unibas.ch/open-positio...

Congratulations to the entire team (l to r): Ibrahim Ilik, first authors Lisa Martina and Michal Malszycki and group leader Tuğçe Aktaş! Work is a collaboration with @ferhatay.bsky.social at the @lji.org and Cantas Alev at Kyoto University. -> Original Publication: doi.org/10.1016/j.ce...

New paper in @cellpress.bsky.social by the Aktas lab @aktast.bsky.social! The scientists show that nuclear speckles help process RNA transcribed from dense regions of the genome, providing an answer to the long-standing question of speckle function. Read more: www.molgen.mpg.de/news-2026-nu...

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

I would like to hear your thoughts on something: paper accepted (Yay! 🥳) but we need to shorten it (like half) to get the final acceptance. We think it's going to be very dense and difficult to understand. Should we post the long version on e.g. our website or what should we do?

IMPRS-BAC Open Call: Current IMPRS student Marcel Wittmund talks about what pursuing a PhD means to him and how the IMPRS program supports his doctoral studies at the MPIMG. Apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj... #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de

🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social 📩 Questions? Contact us ✉️ 🔗 Apply here: www.mpg.de/25243280/bio...

Bioinformatician / Data Scientist (m/f/d)

Bioinformatician / Data scientist position in the Aztekin Lab focusing on Structural Regeneration and support the working group together with the other members

mpg.de

Looking for a master student to help with a superexciting EU-funded project on mRNA metabolism. It'll involve cutting-edge sequencing and imaging techniques as well as computational workflows and modelling - great training opportunity! Get in touch if interested humantechnopole.it/en/research-...

Legnini Group - Human Technopole

Laboratory for Molecular and Systems Biology of RNA   The Legnini Group at Human Technopole combines molecular and systems biology approaches to study gene regulation. We use synthetic biology and opt...

humantechnopole.it

Transposon enthusiats: you don't want to miss this story.

Juliane Glaser@julianeg.bsky.social · last yr.

Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁 Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

New Online! Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease

Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease

Nature Reviews Molecular Cell Biology, Published online: 30 June 2025; doi:10.1038/s41580-025-00867-8Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppression and regulate endogenous genes in development and disease, and emerging therapeutic strategies that exploit TE derepression.

bit.ly

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease. www.nature.com/articles/s41...

Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease - Nature Reviews Molecular Cell Biology

Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppressio...

nature.com

📢 Don't miss! Wayo Matsushima of École polytechnique fédérale de Lausanne (EPFL) will speak at our #DahlemColloquium! 📜 Gene regulatory evolution driven by transposable elements and their controllers 📆 20. JUN, 11:00 AM (CET) 📍MPIMG, Berlin 🔗 www.molgen.mpg.de/events/41978...

In @nature.com Yaotian Zhang and @henriniskanen.bsky.social from the Hnisz Lab discovered a micropeptide, the "Killswitch," which alters the physical state of biomolecules in condensates. This tool solidifies dynamic, liquid-like droplets, affecting their function. --> www.molgen.mpg.de/4884827

Congratulations neighbors! We are very happy to be part of this story and looking forward to the future work we'll be doing with the Hnisz lab 😉

Henri Niskanen@henriniskanen.bsky.social · last yr.

What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments play a key role, and can be probed by a micropeptide killswitch in live cells. www.nature.com/articles/s41... in @nature.com ‬ with @yaotianzhang.bsky.social Denes Hnisz & team.

The awesome Helene Kretzmer and I are looking to recruit a join computational PhD student. Applications will be evaluated on a rolling basis, so don't wait! Any questions get in touch. We are looking forward.

How to find binding sites or your favorite #RNA binding protein? Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy Learn more and register here: meetings.embo.org/event/25-icl... @embo.org @mixmue.bsky.social

iCLIP2, mapping protein-RNA interactions: from A to Z

RNA is increasingly recognized as a key therapeutic target , driving the development of RNA-based therapeutics for a broad spectrum of diseases. RNA-binding proteins (RBPs) play a fundamental ro…

meetings.embo.org

Don't miss the first edition of the CSH-Asia meeting on "The Repetitive and Mobile Genome" taking place in Suzhou, China. 📅 Abstract submission deadline extended: Feb 21, 2025 👉 www.csh-asia.org?content/2544 #transposon #mobileDNA #TEsky

CSH Asia is organising its first transposon meeting. Don't miss out on some great science and a fantastic trip. Abstract deadline fast approaching. www.csh-asia.org?content/2544

🎉 Excited to announce job openings in our new lab @mpi-bio-fml.bsky.social in Tübingen!🇩🇪Looking for enthusiastic colleagues to explore regeneration together! We have positions for: 🔬 Research Technician 💻 Bioinformatician 🎓 PhD Studentship 🧪🔬📖 Postdocs Details and links below👇

The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring? Apply before Feb 15th 📌