Very excited to be sharing our new paper, just out in Nature Cell Biology! The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?

Alright, I am pausing my social media break to share with you the final review of my PhD erra (times fly by 🥲). Featuring 2 of my favorite science fields: #RNAbiology and #celladhesion 😍. Also a fantastic collab with one of my top #women_in_sci role models: Stavroula Mili 💙

ICYMI - we're hosting a new quarterly webinar series on cell migration! In our first webinar on Thursday 11 June at 15:00 BST (UTC+1), we'll hear talks from @juanmagararc.bsky.social, @kyohalie.bsky.social & @djcohen.bsky.social. focalplane.biologists.com/2026/05/29/n...

FocalPlane @focalplane.bsky.social · 2mo ago

We are excited to announce another new webinar series, this time on cell migration, hosted by @pjsaez.bsky.social & @valeriaventurini.bsky.social. In our 1st webinar, we’ll hear talks from @juanmagararc.bsky.social, @kyohalie.bsky.social & @djcohen.bsky.social. 🗓️11 June, 15:00 BST

That’s a wrap for #JCSimaging, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti. Thanks to everyone who joined us and made the conference such a wonderful community event. journals.biologists.com/jcs

A new label-free nanoscale imaging technique has revealed intricate cellular behaviours previously invisible to conventional microscopes. science.anu.edu.au/news-events/...

Thrilled to share that our team’s latest work is now live in @natcomms.nature.com ! 🔬, we established RO-iSCAT (speckle-free iSCAT) and use it to track membrane protrusions in 3D. *Online* www.nature.com/articles/s41... *PDF* rdcu.be/fiFM3 *Press* www.eurekalert.org/news-release...

Using rotational integration of oblique interferometric scattering to track axial spatiotemporal responses of tubular membrane protrusions - Nature Communications

The authors develop RO-iSCAT, which uses rotational integration of off-axis oblique-illuminated interference scattering signals to remove speckle noise in real time. It enables fast, label-free imagin...

nature.com

A clear/significant finding derived from the single cell (sc) analysis of biological systems has been the realization that phenotypically homogeneous populations are heterogeneous at the level of gene expression (GE). www.cell.com/fulltext/S00... 🧵

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

Gene expression is a fundamentally stochastic process, with randomness in transcription and translation leading to cell-to-cell variations in mRNA and protein levels. This variation appears in organis...

cell.com

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

Meet MagLuc: a magnetically-controlled luminescent protein. This is a foundational tool for remote control of biological processes, also known as "magnetogenetics". Can you tell when the magnetic field turns on and off? From @mariaingaramo.bsky.social and the team at @nonfictionlabs.bsky.social

I'm SO excited to see this new paper from our lab's first PhD graduate @wangjianxiong.bsky.social. An outstanding student with a promising career ahead! A PCP-independent role for Prickle1 in junctional neural tube formation. 🧪🐣 Check it out: www.nature.com/articles/s41...

Using light-activated CRISPR in zebrafish, we triggered synchronized DNA breaks and track the repair process. ⚡🐟⚡ 

 Well ... DNA repair is very different in embryos compared to tissue culture cells. Embryos repair DNA breaks incredibly fast - within minutes! www.biorxiv.org/content/10.6...

Optogenetic control of mechanotransduction based on light-induced homodimerization of talin url: journals.biologists.com/jcs/article-...

Optogenetic control of mechanotransduction based on light-induced homodimerization of talin

Integrin-based adhesion complexes serve as primary sites for actomyosin force transmission to the extracellular matrix, providing traction that drives cell mechanical responses including adhesion, mig...

journals.biologists.com

We've integrated FRAP, HILO, and TIRF microscopy into a single setup, driven entirely by a single SLM. Check out the details! #Microscopy #CellBiology #OpticsExpress opg.optica.org/oe/fulltext....

This blowing my mind 🧪

tal boger@talboger.bsky.social · 12mo ago

On the left is a rabbit. On the right is an elephant. But guess what: They’re the *same image*, rotated 90°! In @currentbiology.bsky.social, @chazfirestone.bsky.social & I show how these images—known as “visual anagrams”—can help solve a longstanding problem in cognitive science. bit.ly/45BVnCZ

🚨Job Alert: My department in UNSW Sydney is recruiting a teaching-only Lecturer in Biophysics. The lecturer will play a key role in the pedagogical development and delivery of courses and practicals in the new undergraduate (BSc) major in #Biophysics that we are launching from 2026. #AcademicBsky 🧪

Pleased to share that a SLM can achieve multiple FRAP to HILO to TIRF. biorxiv.org/content/10.1... (to appear in Opt Exp opg.optica.org/oe/home.cfm). Great work done by Avinash www.linkedin.com/in/avinash-u... and Daniel linkedin.com/in/daniel-li... from the team.

We are recruiting for an academic position (Assoc Prof/Prof) in Optical and Photonic Engineering in Oxford. Please share. Closing date 9 September 2025. my.corehr.com/pls/uoxrecru...

WAVE complex forms linear arrays at negative membrane curvature to instruct #lamellipodia formation, say Muziyue Wu, Orion Weiner @oweinerlab.bsky.social and colleagues: rupress.org/jcb/article/... #Biophysics #Cytoskeleton #Migration #Motility #Actin

Publishing scientific papers is an obstacle course. There are many aspects to this but lengthy review times are one. That's why I am very excited about the new initiative @biologyopen.bsky.social, @biologists.bsky.social open access journal: Fast & Fair 1/n 🧪 journals.biologists.com/bio/pages/fa...

Excited to share our new review with Emmanuel on tissue patterning in organ morphogenesis! We explore how repetitive patterns form, starting with the concept of L-systems and highlighting an ERK-mediated curvature feedback. Please check it out! sciencedirect.com/science/arti...

Curvature feedback for repetitive tissue morphogenesis – Bridging algorithmic principles and self-regulatory systems

Tissue patterning during organ development consists of intricate morphogenetic processes, driven by the interplay of physical and genetic cues among c…

sciencedirect.com

Join us in Singapore in September for the "Mechanobiology in Time and Space" meeting hosted by the Mechanobiology Institute at NUS @mbisg.bsky.social and Max Planck Society @maxplanck.de. Abstracts due soon! www.mbi.nus.edu.sg/events/mbico...

Combining Multi-site FRAP and HILO-TIRF microscopy using a Spatial Light Modulator https://www.biorxiv.org/content/10.1101/2025.04.15.649016v1

Adaptive Optics summer school - early registration deadline coming up on 14 April. Register soon to get reduced price.

MMartin J Booth@profmartinjbooth.bsky.social · last yr.

Registration is open for the European Adaptive Optics Summer School, to be held at the Institut d’Optique near Paris, France 9th – 13th June 2025. Topics cover the basics of adaptive optics across applications in vision science, ophthalmology, astronomy, microscopy, free space optics and beyond.

📝 New preprint! 📝 Happy to share a new preprint from @kimboonekamp.bsky.social and me: We developed a 3D force inference method for budding organoids! biorxiv.org/content/10.1... From the labs of @ulrichschwarz.bsky.social and @michaelboutros.bsky.social with help from U. Engel. Here the details.

bioRxiv Biophysics@biorxiv-biophys.bsky.social · last yr.

Fully three-dimensional force inference in intestinal organoids reveals ratchet-like bud stabilization https://www.biorxiv.org/content/10.1101/2025.04.02.646749v1

Getting tissue stress from images is tough, and elastic tension sensors are a way to solve this. Still, the analysis is complex. Try our GUI gitlab.gwdg.de/betzlab_publ... implementing analytical solutions to obtain surface stresses AND shape parameters of beads and nuclei.

Also check out the related work led by Boaz Mohar. Pulse-chase labeling with permeable HaloLigand dyes probes protein turnover. www.nature.com/articles/s41...

DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning - Nature Neuroscience

Researchers developed DELTA, a method for brain-wide measurement of synaptic protein turnover with single-synapse resolution, providing a powerful tool to localize and study mechanisms underlying syna...

nature.com

Imaging throughput of compact handheld microscopes for quantitative single cell studies www.biorxiv.org/content/10.1... Using rotational integration of oblique interferometric scattering (RO-iSCAT) to track axial spatiotemporal responses of membrane protrusions www.biorxiv.org/content/10.1...

Great to be part of a fantastic community event with so much more to discover! Great science and fun Thanks to Leslie Yeo, Dario Carugo, Jessie Jeon, Christoph Westerhausen & @dfrivas.bsky.social for putting together such a wonderful meeting on high frequency mechanostimulation #sonomechanobiology

Imaging throughput of compact handheld microscopes for quantitative single cell studies https://www.biorxiv.org/content/10.1101/2025.03.24.645046v1