TBH my main takeaway from The Odyssey viewing experience yesterday was that John Leguizamo continues to be a national treasure, and yes, everything is too loud for me now.

New research from @daslabpombe.com shows that cell-cycle phase-dependent differential gene expression promotes the transition from monopolar to bipolar growth in #yeast Schizosaccharomyces pombe. Find out more in #G3journal 🔗 buff.ly/ZCVyAs7

Arp2/3-dependent #endocytosis ensures #Cdc42 oscillations by removing Pak1-mediated negative feedback. from Marcus Harrell, Ziyi Liu, @daslabpombe.com and colleagues: rupress.org/jcb/article/... 📕 Part of "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...

Day 10. Good bye Rome. Heading home after the most meaningful experience of life. This is a gift I will hold and cherish forever. I made some really good friends along the way. The places we visited were magical, the food exquisite but it really was the compania that made this trip such a success.

Maitreyi Das@daslabpombe.com · last mo.

Day 9. Started the day with Mass in the basilica of st. Peter and then had the whole day free to ourselves. Enjoyed a bus tour of the city. Its toooooo hot to walk.

Day 9. Started the day with Mass in the basilica of st. Peter and then had the whole day free to ourselves. Enjoyed a bus tour of the city. Its toooooo hot to walk.

Maitreyi Das@daslabpombe.com · last mo.

Day 8. We got to listen to the president of the Gregorian University, Fr. Mark Lewis, audience with the pope, saw the tomb of st. Peter in the vatican and visited the church of Gesu.

Day 8. We got to listen to the president of the Gregorian University, Fr. Mark Lewis, audience with the pope, saw the tomb of st. Peter in the vatican and visited the church of Gesu.

Maitreyi Das@daslabpombe.com · last mo.

Day 7. Good bye Barcelona, hello Rome.

Day 7. Good bye Barcelona, hello Rome.

Maitreyi Das@daslabpombe.com · last mo.

Day 6. In Barcelona. Visited the Basilica Santa Maria del Mar and La Sagrada Famalia. The later was the most moving experience I have had in this trip so far.

Day 6. In Barcelona. Visited the Basilica Santa Maria del Mar and La Sagrada Famalia. The later was the most moving experience I have had in this trip so far.

Maitreyi Das@daslabpombe.com · 2mo ago

Day 5 at Manresa. Visited the cave where st. Ignatius wrote his spiritual exercises, and visited a basilica where he prayed. Also got to enjoy black rice for lunch. So so good.

Day 5 at Manresa. Visited the cave where st. Ignatius wrote his spiritual exercises, and visited a basilica where he prayed. Also got to enjoy black rice for lunch. So so good.

Maitreyi Das@daslabpombe.com · 2mo ago

At Montserrat, Spain.

At Montserrat, Spain.

Maitreyi Das@daslabpombe.com · 2mo ago

I got the most amazing gift this summer. I was invited to join the Campania-Ignatian pilgrimage with some wonderful colleagues from @bostoncollege.bsky.social . This has been one of my best experiences. I am currently in Sos del Rey Catolico, Zaragoza in Spain.

I got the most amazing gift this summer. I was invited to join the Campania-Ignatian pilgrimage with some wonderful colleagues from @bostoncollege.bsky.social . This has been one of my best experiences. I am currently in Sos del Rey Catolico, Zaragoza in Spain.

Our newest review on septins as makers & breakers of membrane contacts in J Neurochem Fun writing with new PhD grad (and FASEB Septin Conference A/V Assistant Extrordinaire) TJ Holt Thanks @mcmurraylab.bsky.social @sergemostowylab.bsky.social for input. onlinelibrary.wiley.com/doi/10.1111/...

Septins in the Middle—Makers and Breakers of Membrane Contact Sites

Septins are a family of GTP-binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. G...

onlinelibrary.wiley.com

If you are an ASCB member, please consider nominating a junior colleague with a strong, promising research program who is already demonstrating leadership in their field, department, and the broader community for the WICB Junior Award for Excellence in Research. www.ascb.org/award/women-...

Ah great! Its exam week and Canvas is down. This should be fun.

Little Girl Rubbing Eyes

ALT: Little Girl Rubbing Eyes

static.klipy.com

OK, here we go. This is the good stuff. An awesome and technically innovatie new paper by good friends of mine including @profsharona.bsky.social, Bill Zagotta, and my next-door science neighbors Professor Suzanne Hoppins and grad student Sophie Hurwitz. 1/

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Hurwitz et al. leverage a novel FRET-based approach to quantify conformational dynamics of Mfn1, a member of the dynamin superfamily that mediates mitochon

rupress.org

They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

Why scientists are nervous about fungi

They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

n.pr

I'm excited to tell you about the most recent preprint in my lab, demonstrating that a conserved spindle matrix protein, NPP-21/TPR, is required for the stronger checkpoint in germline cells during embryogenesis in C. elegans

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 4mo ago

NPP-21/TPR is required for developmental control of spindle checkpoint strength in C. elegans https://www.biorxiv.org/content/10.64898/2026.04.13.718277v1

NSF GRFP results are out! Awardees: docs.google.com/spreadsheets... Honorable Mention: docs.google.com/spreadsheets... (Our team members didn't get emails but discovered the lists through Reddit. Confirmed by logging in to the website and checking.) #NSF #GRFP

In their Review, Prasanna Katti, Antentor Hinton, Jr and colleagues discuss how imaging techniques have advanced our understanding of mitochondrial biology. journals.biologists.com/jcs/article/...

A new study from our group, led by Iris Eisermann, of the septin interactome during appressorium development, revealing many new interactors and significantly widening the biological function of septins in fungal pathogenesis. 👇 @thesainsburylab.bsky.social

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 4mo ago

A stage-resolved map of dynamic septin interactions required for infection by the rice blast fungus https://www.biorxiv.org/content/10.64898/2026.04.02.716073v1

Another paper from our awesome lab out today @nature.com. Led by 🌟 PD Jihye Yeon with fantastic collaborators. We show how an ionotropic receptor (related to insect sensory IRs) in a single pharyngeal enteric neuron senses ingested salts and protects the worm from high salt stress. rdcu.be/fbd4a

I’m excited to be on the leadership ballot for an @ascbiology.bsky.social Council position. The past and present Council members are amazing scientists, mentors, and community members, so thank you to whoever suggested that I might be a good fit! It’s honestly an honor even to be nominated. ❤️

a woman in a neon yellow dress says it 's such an honor to be here on snl

Alt: a woman in a neon yellow dress says it 's such an honor to be here on snl

media.tenor.com

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...

Please check out our new preprint! Using single cell analysis paired with HCR to visualize transcript localization we have identified cell and tissue-specific expression of various genes encoding tubulins, kifs, and dyneins during neural crest development!

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · 5mo ago

A spatial and temporal atlas of tubulin isotype expression during neural crest EMT https://www.biorxiv.org/content/10.64898/2026.03.04.709627v1

just got my summary statement 😭😭 and as I gear up to write a MIRA (re)submission, I'm trying to INTERNALIZE this thread: more declarative statements, less hedging more leading w/ conclusions, less leading w/ data more broad and expansive language, less narrow language maybe it'll work? 🤷🏽‍♀️

AZ Faust@azfaust.bsky.social · 6mo ago

These days, more than ever, you need an enthusiastic advocate on the study section. You need someone who is going to go to bat for your grant and convince other reviewers and the other members that this is the project that will solve that big, outstanding problem in the field.

More than 2,000 people gathered on Capitol Hill to worship, sing and march to bring attention to the plight of immigrants in the United States. The event brought together United Methodist bishops, clergy and laity alongside faith leaders from several traditions. www.umnews.org/en/news/unit...

United Methodists lead witness for immigrants | UMNews.org

More than 2,000 people of faith marched around the U.S. Capitol to witness to the Christian faith and to let immigrants know that they do not stand alone.

umnews.org

Postdoc job alert in the Crick Institute in London. Are you interested in the actin cytoskeleton? I am looking for a postdoc to examine the cellular, developmental or physiological role of Arp2/3 iso-complex driven actin polymerisation. Multiple aspects available. crick.ac.uk/WayPostdoc2026

I am finally getting around to discussing our preprint "Septins mediate cell-cycle-dependent exclusion of Cdc42 GAP Rga4 from growth sites in fission yeast" by a very talented grad student Justin McDuffie in the Das lab. www.biorxiv.org/content/10.1... 1/

New preprint from us and our friends in the Odorizzi lab at CU-Boulder – we find an apparent role for septin cytoskeletal filaments and vesicle transport from the Golgi to the vacuolar lysosome in budding yeast.

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 6mo ago

Septins associate with AP-3 to support trafficking to the vacuole/lysosome in yeast https://www.biorxiv.org/content/10.64898/2026.02.13.705769v1

Cdc42 is a small GTPase crucial for #CellPolarity, but how does it contribute to #aging when upregulated? This study shows that the ER-anchored chaperone Ydj1 interacts with Cdc42, enhancing its stability & partitioning during asymm #CellDivision & aging in yeast @plosbiology.org 🧪 plos.io/4qz7WaM