Andrew Maclean

@macleanlab.bsky.social

MRC research fellow at the University of Edinburgh working on parasite metabolism.

This week, our paper came out in @jem.org showing that: This week, our paper came out in @JEM showing that: 1. Long-lived Tim-4+ macrophages are present in the lamina propria and submucosa/muscularis. 2. Macrophage-derived TGF-beta is key to instructing macrophage identity in the lamina propria.

Journal of Experimental Medicine@jem.org · 4mo ago

New study from Jayaraman, Prise, et al. from the Grainger & @tovah-shaw-lab.bsky.social labs @edinburghbiology.bsky.social @lydiabeckeriii.bsky.social challenges the prevailing paradigm that long-lived gut #macrophages are restricted to the muscularis. rupress.org/jem/article/...

It feels cheesy when people say this but it really was a privilege to be part of this work. Our recent paper (led by the fantastic Ben Royer @swallacelab.bsky.social) shows how engineered Ecoli can turn the main product of PET plastic breakdown it into an anti-Parkinsons drug (L-DOPA) rdcu.be/e84ZO

Microbial upcycling of plastic waste to levodopa

Nature Sustainability - The production of high-value chemicals can involve energy-intensive processes, necessitating sustainable production strategies. Here the authors present a circular...

rdcu.be

Like #hemocytes? I'm advertising a 3 year, BBSRC #postdoc position, in #Edinburgh, using #Drosophila & human cells to understand sex differences in the regulation of #macrophage function, an exciting collaboration with the Bénézech and Wood labs. Please share! 🪰🏴󠁧󠁢󠁳󠁣󠁴󠁿 www.jobs.ac.uk/job/DQU604/p...

Postdoctoral Research Associate at The University of Edinburgh

Discover an exciting academic career path as a Postdoctoral Research Associate at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

jobs.ac.uk

📆 Join us for the scientific session of the ParaFrap Next Generation in Parasitology Workshop (May 18-21, 2026, Montpellier) ! 🧑‍🔬 Junior PIs will present their work. Registration is free but mandatory (includes lunch & coffee breaks). Spots are limited, register now! 👉 forms.gle/bYsb47iZG7pR...

Bild

A great collaboration of my group with @herassr.bsky.social and @heick.bsky.social groups searching for mammalian dsRNAs and their importance to human disease 🧬

Ana Gázquez-Gutiérrez@anagazquezg.bsky.social · 5mo ago

I'm so happy to share our latest paper! Now out in @narjournal.bsky.social 🥳 Did you know that transposable elements embedded in mRNAs can form dsRNA and activate innate immunity? 🧬🦠 Have a look! academic.oup.com/nar/article/... #TEsky #RNAsky #RNAbiology #immunity #NAR

🚨 Postdoc position 🚨 I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026). Details & application: jobs.uzh.ch/job-vacancie.... Please share! 😊

UZH: Postdoc

The newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl...

jobs.uzh.ch

Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunity👇🏾

Bild
bioRxiv Plant Bio@biorxiv-plants.bsky.social · 6mo ago

Ubiquitin recognition integrates plant immune signaling by cell-surface and intracellular receptors https://www.biorxiv.org/content/10.64898/2026.02.06.703835v1