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@mnprioleau.bsky.social

Group leader@ijmonod. Studying DNA replication and genomic instability

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Julian Sale@juliansalelab.bsky.social · 5d ago

Working with a hugely engaged group of editors (all of whom are practising scientists), authors and reviewers, and a great publisher, is a hugely rewarding way to contribute to the community. Your chance to get involved!

Nucleic Acids Research@narjournal.bsky.social · 6d ago

📣NAR is recruiting a new Executive Editor!📣Seeking an established researcher with expertise in RNA biology and translation mechanisms to help shape the journal's scientific direction, oversee peer review, and support its growth. Apply by 30 Sept 2026: academic.oup.com/nar/pages/ex...

Development@dev-journal.bsky.social · 3w ago

In preprints – housekeeping the housekeeping genes Maxim V. C. Greenberg @maxvcg.bsky.social writes about two complementary preprints by the @grandlab.bsky.social & @schubelerlab.bsky.social labs that elucidate the mechanistic framework of essential gene expression. doi.org/10.1242/dev....

In preprints – housekeeping the housekeeping genes

The term ‘housekeeping gene’ evokes a sense of banality. These are the boring genes that hum in the background, impervious to cell state or stress. For a developmental biologist captivated by the…

doi.org

Aga Gambus@agagambus.bsky.social · 3w ago

We’ve been awarded European Commission Choose Europe for Science Co-fund at Uni of Birmingham! MOBILITY will fund 6 talented postdoctoral researchers at the transition to independence. All within remit of Molecular Biodiscovery. Applications open in October 😀👍. www.birmingham.ac.uk/news/2026/bi...

First UK institution awarded Choose Europe for Science grant - University of Birmingham

Birmingham awarded £1.2m in ERC funding to attract talent from outside of Europe

birmingham.ac.uk

Dirk Remus@dirkremus.bsky.social · 2mo ago

If you have experience in biochemistry/cryo-EM, are interested in DNA replication, and would like to do a postdoc in New York - our lab has positions available! Just DM or email me with your CV.

Maxim Greenberg@maxvcg.bsky.social · 2mo ago

🚨Preprint Drop🚨 We are very pleased to release our study on DNA methylation dynamics at enhancers during ESC differentiation! This work was led by Marlet Morales-Franco and Priscillia Lhoumaud 🧵(1/13) www.biorxiv.org/content/10.6...

Dual profiling of DNA modifications with enhancer features during the exit of naive pluripotency

Cis-regulatory elements, such as enhancers, play an essential role in coordinating gene expression programs during cellular transitions. As such, substantial efforts have been made to characterize enh...

biorxiv.org

@sandraduharcourt.bsky.social · 3mo ago

Please join the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination in Roscoff, France. Deadline for abstract submission extended to May 20, 2026. cjm.sb-roscoff.fr/en/conferenc...

The mechanistic and evolutionary basis of programmed DNA elimination | CNRS - Conférences Jacques Monod (CJM)

cjm.sb-roscoff.fr

@sandraduharcourt.bsky.social · 3mo ago

The Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination is approaching. There are selected talk slots available. Abstract submission deadline: Tuesday, May 5, 2026.

Bruno Miroux@brunomiroux.bsky.social · 3mo ago

Investissement en R&D. Il a fallu 27 ans à 21 pays européens pour augmenter leurs dépenses en recherche et développement de 0,8 % en moyenne de leur PIB. Il faudra 30, 40, 50 ans à la France pour rattraper l’Autriche ou la Belgique!

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Kasia Siudeja@ksiudeja.bsky.social · 4mo ago

📣📣 Deadline approaching 📣📣 (Please re-post) If you are thinking of starting (or moving) your lab, do not miss the opportunity to apply to join us at the @i2bcparissaclay.bsky.social Diversity of topics, interdisciplinary environment and excellent platform support! Recommended!

@i2bcparissaclay.bsky.social · 5mo ago

We are looking for outstanding scientists to develop ambitious research programs in molecular and cellular biology, with special interest in multidisciplinary projects and computational biology.More info: www.i2bc.paris-saclay.fr #MolecularBiology #CellBiology #ComputationalBiology #TeamLeaders#I2BC

@sandraduharcourt.bsky.social · 4mo ago

Our latest publication is now out at Genome Biology! link.springer.com/article/10.1... We uncover a unique association between a H3K27me3 reader complex and active transcription. A thread with our key findings: (1/8) #TEsky #Polycomb #transcription #smallRNAs

A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology

Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...

link.springer.com

Aurele Piazza@aurelepiazza.bsky.social · 5mo ago

Our OA author manuscript is always available here: hal.science/hal-05520503

Spatial controls of homology search

Homologous recombination is a conserved DNA double-strand break (DSB) repair pathway that uses an intact dsDNA molecule as a template. A filament of the RecA/Rad51 protein family catalyzes the search for this homologous template, in a process that minimally requires the collision of these two partners in the nuclear space. Orthogonal methodological developments recently revealed that this search for homology is a choreographed process under control by both 3D chromatin organizers of the structural maintenance of chromosomes (SMC) family and the structure and dynamics of the RecA/Rad51 filament. Here we review these advances that establish a novel framework for homology search, highlight the commonalities and distinctions between search facilitation strategies in eukaryotes and bacteria, and discuss outstanding open questions.

hal.science