Lorena Oli
@olifiersl.bsky.social
PhD student at the Max Planck for Biological Intelligence & GSN-LMU I like to find out what makes our muscles move 🔬 #nerdfighter
🧠 What if #LongCovid is, in part, a disorder of dopamine? Our new commentary explores how disrupted dopamine signaling may help explain fatigue, brain fog, and autonomic dysfunction, and what this could mean for future therapies. Open access link: shorturl.at/vLAfU
Chantzy@chantzy.bsky.social · 4w ago"Our findings provide compelling evidence that long COVID involves the loss of dopamine-releasing neurons," says Dr. Jeffrey Meyer, senior scientist at the Brain Health Imaging Center, Canada Research Chair medicalxpress.com/news/2026-07...
Losing one side of Superior Colliculus is bad, but losing both sides seems fine. Wait, what? Flora & team discovered why: both sides press for contra actions and against inaction, obeying an incredibly simple additive rule. Out today in bioRxiv: www.biorxiv.org/cgi/content/...
"would you still love me if I had no cortex" is a neuroscientist's equivalent of "would you still love me if I was a worm"
How do sperm and egg fuse? Surprisingly, we still don’t fully know… Our field has uncovered many pieces of the fertilization puzzle, but not how they fit together. We identify ✨ SPARK ✨ - a conserved sperm complex that couples sperm-egg binding to fusion. tinyurl.com/34cm4xat Read on! 🧵👇
academic couples really be out here making meals for when their significant other comes home at 11pm 🥺🥺🥺
The Landoni Lab opens this summer at UNIL! @fbm-unil.bsky.social 🔬 Quantitative #imaging + systems biology to decipher how #metabolic architecture & #mtDNA dynamically shape tissue development, #aging and #mitodisease. Beyond excited to fire up the lasers, open positions soon! 🧪 #mitochondria #newPI
Congratulations to Tim @timayupov.bsky.social, Kika @vmorenojuan.bsky.social and everyone on the team for their wonderful paper on the targeted delivery of mitochondria published in Nature today 🥳 Couldn’t be prouder of you! www.nature.com/articles/s41...
Cell-type-targeted mitochondrial transplantation rescues cell degeneration - Nature
MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.
nature.com
Every scientist is a bit of an artist and every artist is a bit of a scientist
Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]
Early demyelination by off-target complement injury in a mouse model of neuromyelitis optica https://www.biorxiv.org/content/10.64898/2026.03.13.711636v1
⚡️We are excited to share a new paper from the lab by @drkhole.bsky.social in @cp-cellrepmethods.bsky.social - suggesting MitoTracker dyes are not a reliable tool for detecting intercellular mitochondrial transfer❗️ www.cell.com/cell-reports...
MitoTracker transfers from astrocytes to neurons independently of mitochondria
The mitochondrial dye MitoTracker is commonly used to investigate intercellular mitochondrial transfer (IMT), particularly between astrocytes and neurons. Hole et al. compare MitoTracker with a geneti...
cell.com
🧠Constitutive neuronal expression and disease-associated upregulation of #chitinases in #amyotrophiclateralsclerosis 🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...
Bucket list goal accomplished: having my question answered by Hank & John (minute 4:30) open.spotify.com/episode/17w4...
436: The Kelce Green Brother Bowl Brawl
open.spotify.com
Local demyelination rekindles oligodendrocyte precursor dynamics and remyelination in old age https://www.biorxiv.org/content/10.64898/2026.02.15.705983v1
The amount of people left stranded in #BadEndorf by @deutschebahn.com with no shelter and no way of getting home. If you come to Germany: DONT TAKE THE DEUTSCHE BAHN!!! also, happy Valentine's day 🫠
Check out my first @prelights.bsky.social article, based on some great work done by Dr. Tejashree Waingankar & @samlewis.bsky.social at UC Berkeley 🔬🧬🧠 prelights.biologists.com/highlights/s...
Self-renewal of neuronal mitochondria through asymmetric division - preLights
Neurons contain “hotspots” for mitochondrial biogenesis at distal branch points
prelights.biologists.com
The moment to celebrate a paper is when it’s shared with the world, not when it passes the arbitrary hurdle of “acceptance”
Schwarz lab @bostonchildrens.bsky.social identify a mechanism coupling mitochondrial movement to energy demand. When energy levels are low, the energy-sensing kinase AMPK phosphorylates the motor/adaptor protein TRAK1, arresting #mitochondria via the #actin #cytoskeleton. rupress.org/jcb/article/...
Research with fruit flies could unlock riddle of neurodegenerative disorders www.manchester.ac.uk/about/news/r... by @manchester.ac.uk #Alzheimers #dementia #Parkinsons #MND #neuroscience #NeuroSkyence
Research with fruit flies could unlock riddle of neurodegenerative disorders
A study by University of Manchester scientists using fruit flies as model has identified a mechanism which can explain aspects of neurodegeneration which have baffled scientists for decades.Scientists...
manchester.ac.uk
Loss & gain of motor protein function cause microtubule bundle damage in 🪰 axons: @currentbiology.bsky.social Biology www.cell.com/current-biol... @poppi62.bsky.social
Loss and gain of motor protein function cause microtubule bundle damage in Drosophila axons
Liew et al. show that neurodegeneration-linked mutations of different transport motor classes cause damage to axonal microtubule bundles in the form of microtubule-curling. Transport loss of mitochond...
cell.com
My quote of the day I must uphold my ideals, for perhaps the time will come when I shall be able to carry them out. Anne Frank
New preprint from my lab!!! We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
Mitochondrial hitch-hiking of Mapt mRNA maintains Tau levels in axons
Hitch-hiking of transcripts on organelles, including mitochondria, has emerged as a common pathway to transport mRNAs into the axon to enable their local translation. However, the extent of mitochondr...
shorturl.at
🚨 REGISTRATION NOW OPEN – CAJAL CONFERENCE 2026 “Novel Insights Into Brain Energy Metabolism in Health and Disease” 📍 April 15–17, 2026 | Cádiz, Spain 🔔 SENC Fellowships available 🔔 20 slots for Oral Communications 👉🏻 Register here: amconferences.eventsair.com/senc-cajal-c... 👇🏻 SPEAKERS
How do cells assess mtDNA quality? Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection. We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae. Great collaboration with the Schmoller Lab. journals.plos.org/plosgenetics... 🧬⚡
Local mitochondrial physiology defined by mtDNA quality guides purifying selection
Author summary Mitochondria are essential organelles in our cells that convert nutrients into usable cellular energy. They contain their own DNA, and mutations in this DNA can compromise mitochondrial...
journals.plos.org
www.nature.com/articles/s41...
Mitochondrial transfer from glia to neurons protects against peripheral neuropathy - Nature
Mitochondria that are transported from satellite glial cells in dorsal root ganglia to peripheral sensory neurons through tunneling nanotube-like structures provide protection against peripheral neuro...
nature.com
🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)! An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools. 🗓️ Apply online by Jan 30, 2026
Quantitative Imaging: From Acquisition to Analysis
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
meetings.cshl.edu