Single author work by Dr. Wieschaus with lovely microscopy 🧪🤩! from the discussion:Although powerful, the logic behind [mutant] approach is always indirect, given that the phenotype one sees is produced by the genes that remain, not the gene that was removed. journals.biologists.com/dev/article/...

Maternal patterning in early Drosophila embryos: how much information can single maternal gradients supply?

Highlighted Article: Comparison of the patterning capacity of Drosophila embryos that have only one of the three maternal gradients known to control anterior posterior patterning.

journals.biologists.com

Come join us! 🔬🐣 The Piacentino Lab at Johns Hopkins @hopkinsmedicine.bsky.social is recruiting a postdoc to study membrane lipids, cell migration, and invasion in neural crest and embryonic models! @socdevbio.bsky.social @ascbiology.bsky.social #devbiol #cellbio #lipids

Join us on a journey into the dynamics of cells during embryo development. We are offering a fully funded PhD position to investigate cell behavior using cutting-edge quantitative live imaging at the interface of Development, Immunity, and Tissue Biology. embryobioimaging.com

Most distant #organizer transplants arrived: #cells from ctenophore convince a cnidarian to make a second embryo axis! Organizers (possibly) are pushed back to eumetazoan ancestor... 🧪 www.nature.com/articles/s41...

A blastoporal organizer in a ctenophore - Nature

Experiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a core signalling pathway may have been a key innovation enabling the transit...

nature.com

1 week to start🔥 New @focalplane.bsky.social webinar series focused on #CellMigration, register & join us▶️, it will be fun! pls spread the word, in the next one, ECRs could apply to show their work ;) ▶️ to register: focalplane.biologists.com/2026/05/29/n... @dgz.bsky.social @the-node.bsky.social

SAVE THE DATE for the 13th Canadian Developmental Biology Conference — March 7–10, 2027 — bringing together researchers, trainees, and innovators in developmental biology from across Canada and beyond.

It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪

We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply! #optogenetics #metabolism #devbio #hESCs Please RT. Thank you!🙏

Institute of Molecular Biotechnology@imbavienna.bsky.social · 6mo ago

Apply to the Master’s project position at IMBA: https://www.oeaw.ac.at/imba/career-education/open-positions/pos2607-masters-project #research #jobs #europe #biology

I am thrilled to share our paper introducing RBPscan, a novel approach to profile RNA–protein interactions in living cells. Free access link at the end ⬇️ 🧵 1/ www.cell.com/molecular-ce...

RBPscan: A quantitative in vivo tool for profiling RNA-binding protein interactions

Kretov et al. introduce RBPscan, an RNA-editing-based platform that measures how RNA-binding proteins engage their targets in living cells. This approach quantifies the binding strength of protein-RNA...

cell.com

#Canada 🍁 has opened prestigious CIRTA fellowship for internationally based candidates in Ph.D. and postdoctoral levels. We (Physical biology of developing systems lab at McMaster University) are interested in recruiting through that stream. Please apply / spread the word for those interested:

Oh my god, @biologyopen.bsky.social put this newbie next to John Gurdon in their @biologists.bsky.social 100-year anniversary cover dedicated to reviewers! What a lovely gift and coincidence for closing the year... 🤩

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

Modelling co-development between the somites and neural tube in human trunk-like structures - Nature Cell Biology

Makwana, Tilley et al. generate human stem cell-based trunk-like structures approximating Carnegie stage 13–14 of development. They use them to model and study the development of the thoracic and lumbar trunk.

nature.com

#FluorescenceFriday bleed-through from yesterday #zebrafish 🐟🔬:

We are hiring an Imaging Scientis. Apply here: go.mbl.edu/AS1887

A picture snapped with phone camera today: a rare 'supernumerary' #rainbow over Hamilton with repeating colour sequence due to very small droplet sizes giving rise to interference patterns of #light by its #wave nature. 🧪

Fascinating timelapses of #somite clock with cadherins from Kageyama Lab @dev-journal.bsky.social : journals.biologists.com/dev/article/...! A new player in clock and #fgf gradient cross-talk besides previously discovered Dusps linking both transcriptional and post-translationally. 🧪🔬 #devbio

New BBSRC funded PhD opportunity in my group with Inspiralis Ltd and @conradn.bsky.social. If you are interested in RNA - protein interactions and RNA modifications check the details below for how to apply. @nrpdtp.bsky.social @biouea.bsky.social @earlhaminst.bsky.social tinyurl.com/bdzvn4dr

How do RNA molecules shape genome regulation in the nervous system? (AKAY_U26CASE) | Doctoral Training Partnership

This PhD project will investigate how RNA modifications influence the activity of topoisomerase I (TOP1), a crucial enzyme that regulates DNA supercoiling during replication and transcription. Using C...

biodtp.norwichresearchpark.ac.uk

It was one-of-a-kind moment to meet Sir John Gurdon at @socdevbio.bsky.social meeting in 2019. Such a humble, down-to-earth personality who was deeply content with life! An exemplary scientist that one could find at the benchside playground regardless of age or career stage! May he rest in peace...

Xenbase@xenbase.bsky.social · 10mo ago

Prof. Sir John Gurdon (1933-2025). It is with great sadness that I share the news of the death of a father of the Xenopus field, Professor Sir John Gurdon. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

1/5 Lab's first manuscript 🎉 is out @biorxivpreprint.bsky.social today! Beautifully, it is performed by a senior undergraduate thesis student, Mohammed! We developed a 3-D printed #zebrafish embryo imaging chamber 🔬and connected it to syringe pumps to be able to perfuse drugs in a timely fashion. 🧪

🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/

I am excited to announce that I will be moving to IMB Mainz next year! The Winter call for the IPP PhD program is now open; if you are interested in maternal #mRNA regulation and #translation in early vertebrate development, please apply! Deadline: 16 October. More info: www.imb.de/students-pos...

🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25! 🎤 We have an exciting line-up of speakers this fall. See the image below for details 🌐 Website: sites.google.com/view/devmech... 📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Mathematical modelling of the first fate decision This Research Highlight showcases the work from Maria Avdeeva, Madeleine Chalifoux, Bradley Joyce, Stanislav Y. Shvartsman, Eszter Posfai @eposfai.bsky.social : journals.biologists.com/dev/article/...

Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...

Are different cell types like oil and water? Over a century ago, researchers found that dissociated sponges and embryonic tissues can self-assemble into functional structures. Join me, @benswedlund.bsky.social to explore the differential adhesion hypothesis & its applications in tissue engineering!

CIHR rant here: our panel funded 6 (!!) out of 42 applications. That is only 14% success rate. That is as bad as the worst of times. So much good science left unfunded, labs closing, skilled workers let go. Without a $$ infusion, the Canadian research ecosystem is never going to survive and thrive.

I was interviewed recently by @stemcellpodcast.com I witter on about morphogens, notochord, @dev-journal.bsky.social & how biology is becoming a data science Thanks @stemcellpodcast.com for talking to me stemcellpodcast.com/ep-299-spina...

Ep. 299: "Spinal Cord Development" Featuring Dr. James Briscoe - The Stem Cell Podcast

Dr. James Briscoe is a Group Leader at the Francis Crick Institute and Editor-In-Chief of Development. His lab uses an interdisciplinary approach, including mice, chicks, and other models, to study de...

stemcellpodcast.com

📣 We're on the lookout for a creative postdoc with strong computational skills! Be the go-to person in the lab for building simple but powerful simulations that test wild ideas on biological rythems: from daily cycles of mussel groups at deep sea, to firefly flash synchronization! More info below👇

Have you ever thought about inflating tissues? Or maybe quickly deflating those inflated tissues? New #EpithelialMechanics pre-print: doi.org/10.1101/2025... 🧵 with pressure control, multiscale buckling, controlled wrinkling