Q: What is the only known planet in the Universe to be inhabited entirely by Alien Robots? A: Mars.

#Splicing dysfunction may represent a cryptic form of #genome erosion. This study shows that intron retention freq is much higher in #recombination -suppressed #MatingType regions in 4 #phytoplankton species, producing aberrant transcripts & functional decay @plosbiology.org 🧪 plos.io/44vbDFI

Die AfD ist verfassungswidrig und könnte verboten werden – das ist das Ergebnis unseres umfassenden Rechtsgutachtens. Ein Grund dafür: Die AfD will politische Gegner\*innen unterdrücken. 🧵

"Sie ist wieder da - die Debatte um ein Verbotsverfahren gegen die AfD. Anlass ist ein Gutachten, das zu dem Schluss kommt: Die Partei ist klar verfassungsfeindlich." www.zdfheute.de/politik/afd-...

AfD-Verbotsverfahren: Gutachten löst eine neue Debatte aus

Sie ist wieder da - die Debatte um ein Verbotsverfahren gegen die AfD. Anlass ist ein Gutachten, das die AfD als verfassungsfeindlich einstuft.

zdfheute.de

Interested in hearing about mechanisms of cohesin-dependent vs. -independent enhancer regulation? @karissalhansen.bsky.social will be presenting her work **Tues June 23rd 8am CET** www.biorxiv.org/content/10.6... www.science.org/doi/10.1126/... Thank you @genome-org-aus.bsky.social ! 👇

GOA - Genome Organisation Australia@genome-org-aus.bsky.social · 2mo ago

Only one week to go until our next GOA seminar! @karissalhansen.bsky.social will present here work on the mechanisms of long-range enhancer-promoter communication. Registration link: unimelb.zoom.us/webinar/regi...

Exciting breakthrough technology from the lab, now live in @cellcellpress.bsky.social ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!

Submit today!! Time is running short to present your work at #TT2026 tt2026.org

#RNAsky

Christine Mayr@christinemayr.bsky.social · 2mo ago

Finally out in @Cellcellpress! Proteins with long IDRs are prone to misfolding during protein synthesis. This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones. www.cell.com/cell/fulltex...

Hi everyone! I am a PhD student in virology and I built a completely free iOS app in my free time. Please try it, any feedback is welcome! A repost would help more scientists see it. 📱 apps.apple.com/us/app/cell-... #Biology #PhD #AcademicSky #scicomm #virology #LabLife

Cell Culture and Lab Assistant App - App Store

Download Cell Culture and Lab Assistant by Umut Tank on the App Store. See screenshots, ratings and reviews, user tips, and more apps like Cell Culture and Lab…

apps.apple.com

Seminar Alert: *Prof. Elena Conti* 'RNA exosome complex: Molecular Mechanisms of RNA degradation in health and disease' When: 18.06.2026, 14:00 Where: Haus 22-1 (lecture hall H22-1), Neiderad Campus (Uni KliniK), Goethe University RT🙏 @scale-cluster-ffm.bsky.social @goetheuni.bsky.social

Super happy to see our work published in @nature.com last week 🤩 By combining whole-body tissue clearing, light-sheet microscopy and AI, we mapped obesity-associated remodeling across the entire mouse body in 3D at cellular resolution. www.nature.com/articles/s41... @erturklab.bsky.social

TWO WEEKS to go!!!!! Submit your abstract for TT2026 today #tt2026 #transgenic #GEMM tt2026.org/abstract-sub...

🚨 Excited to share a new paper in Cell! Human genetics led us to HOTSCRAMBL, a HOXA-locus lncRNA that regulates 🩸#stemcell self-renewal and HOXA9 splicing, with implications for AML. Amazing work by @lvchosen1.bsky.social with many others! www.cell.com/cell/fulltex...

The authors of a Comment artcle in Nature outline four key aspects of the drug development and approval process that need updating to make the production of personalized CRISPR therapies economically viable. #medsky 🧬🧪

Personalized CRISPR therapies could soon reach thousands — here’s how

A fresh approach to trialling treatments for rare genetic diseases could make their production an economically viable prospect at last.

go.nature.com

Transcription termination safeguards quiescent chromatin for faithful cell-cycle re-entry https://www.biorxiv.org/content/10.64898/2026.03.28.714970v1

A nice opportunity to repost some great work from Mary Lyon. Transmission Ratio Distortion in Mice - www.annualreviews.org/content/jour...

Transmission Ratio Distortion in Mice

▪ Abstract The most studied example of transmission ratio distortion (TRD) in mice is that of the t-complex. This is a variant region of Chromosome 17 which exists as a polymorphism in wild mice. Male...

annualreviews.org

bioRxiv Genetics@biorxiv-genetic.bsky.social · 5mo ago

Discovery of a Genetic Toxin-Antidote System in Vertebrates https://www.biorxiv.org/content/10.64898/2026.03.04.709565v1

If you want to explore ncRNA dynamics during mammalian development, love microscopy, and are not afaraid of transposons biology, apply‼️ We are looking for a postdoc to join our team at @imbavienna.bsky.social More details 👇🏻

Institute of Molecular Biotechnology@imbavienna.bsky.social · 5mo ago

We are hiring! Join the Jachowicz lab as a postdoctoral researcher. The project focuses on understanding the dynamics of ncRNAs using high-resolution and single-molecule microscopy approaches. Link below 👇

its amazing how chatgpt knows everything about subjects I know nothing about, but is wrong like 40% of the time in things im an expert on. not going to think about this any further

This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...

Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation

Transcriptional adaptation (TA) is a genetic robustness mechanism through which mutant messenger RNA (mRNA) decay induces sequence-dependent up-regulation of so-called adapting genes. How cytoplasmica...

science.org

Attention RNA biology and antisense therapy folks: this is HUUUUUUGE!!! Termination windows as therapeutic opportunity!

Pawel Grzechnik@grzechnikpawel.bsky.social · 6mo ago

Interested in antisense oligonucleotides? Check our story about downstream-of-gene ASOs (DG-ASOs)! Together with the Roche Innovation Center we identified transcription termination windows of protein-coding genes as ASO target regions. link to BioRxiv: www.biorxiv.org/content/10.6...

Be seen at TT2026 in Leiden! Sponsorship and exhibition opportunities are now available for TT2026. Put your brand in front of a global audience and be part of an exciting international conference. ✨ Sponsorship Packages ✨ High-impact Brand exposure 📩 Enquire now: tt2026@in-conference.org.uk

Our atlas of lncRNAs associated with M1 and M2-like phenotype in TAMs in lung cancer is out www.nature.com/articles/s41...

Association of tumour-associated macrophage states with non-conserved lncrnas in lung cancer - Genes & Immunity

Genes & Immunity - Association of tumour-associated macrophage states with non-conserved lncrnas in lung cancer

nature.com

Wir sind bei der Kinotour von "BLAME" in Köln, München und Berlin mit dabei! Der erste Termin findet am 3.2. im Odeon Kino in #Köln statt. Nach der Filmvorführung spricht Regisseur Christian Frei mit Leon Wansleben. Er ist Forschungsgruppenleiter @mpifg.bsky.social 📽️ www.mpg.de/25990221/dok...

AlphaGenome is out in @nature.com today along with model weights! 🧬 📄 Paper: www.nature.com/articles/s41... 💻 Weights: github.com/google-deepm... Getting here wasn’t a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc

Human heart organoids reveal a regenerative strategy for mitochondrial disease https://www.biorxiv.org/content/10.64898/2025.12.18.695153v1

CISTR-ACT was the 1st lncRNA involved in inter-chromosomal contacts and in Mendelian disease (brachydactyly). We now revealed CISTR-ACT’s molecular mechanism: tinyurl.com/CISTR-ACT, @sickkidsto.bsky.social, @uoftpress.bsky.social, @natcomms.nature.com, @natureportfolio.nature.com

A systems genetics approach to uncover mitochondrial drivers of heart failure reveals mitochondria-nuclear cross talk in genetically diverse mouse strains https://www.biorxiv.org/content/10.64898/2025.12.12.693865v1

First day of the #Microbiome Symposium at #Georg-Speyer-Haus organized by LOEWE-FCI professor Canan Arkan was a great success. Thanks to all speakers & supporters (Cathrin Schleussner from Schleussner Stiftung and Martin Zörnig, Else-Kröner-Fresenius-Stiftung). Looking forward to the second day!

Now online! RNA innate immunity constitutes a barrier for interspecies chimerism

RNA innate immunity constitutes a barrier for interspecies chimerism

Interspecies PSC co-culture induces horizontal RNA transfer that activates innate immunity in “winner” mouse cells, a response that is alleviated by Mavs deletion, thereby enhancing “loser” human PSC survival and chimerism.

dlvr.it

🍾🥂 @melanietichet.bsky.social of @loewe-fci.bsky.social is an awardee of the Metastasis Prize of the Beug Foundation 2️⃣0️⃣2️⃣5️⃣. We congratulate👏🏼 and look forward to the progress the research will bring to the treatment of metastatic melanoma in older patients➡️https://www.beugstiftung-metastase.de/tichet/