Happy #dayofimmunoloy! We work hard to understand how our immune system protects us from infection! Thanks to @ukri.org @yorkshirebiodtp.bsky.social MRC and BBSRC to support our research and the development of novel therapies!
Proteases and Innate immunity lab @ York
@protinnimmunity.bsky.social
Immunology lab led by Dr. Dave Boucher, Unravelling how proteases control innate immune responses to infections and diseases Boucherlab.org
The 2026 UK Cellular Microbiology Network Meeting is approaching fast! Submit an abstract until May, 12th and join us June, 22nd/23rd in Belfast! Exiting keynote speakers and opportunities for early career researchers from the UK, Ireland and beyond to share their work. www.ukcellmicro.org
With all the excitement about AI giving us answers, we often forget that the real trick is to figure out what is the question.
Jo in our team - we are looking for a PhD student, postdoc or lab manager! More information and links to job portal for application submission: lnkd.in/dcU2Vg7W lnkd.in/dgVKTARV Please share widely 🙏🏼 @yefis-immunology.bsky.social @syis-ecr.bsky.social
Postdoc or PhD student position in molecular dissection of cellular crosstalk in the intestinal mucosa
lnkd.in
3 PhD positions in the lab for British Students. Inflammasome, cell death and skin immunity, with fantastic colleagues. Check them out or share it with curious and motivated PhD students: www.findaphd.com/phds/?Keywor... @yorkshirebiodtp.bsky.social @ybri-uoy.bsky.social @biologyatyork.bsky.social
dave boucherare PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in dave boucherare. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
findaphd.com
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!
New story from the lab by PhD student Seb Grant. Started as a summer project and developed into an interesting story. www.biorxiv.org/content/10.1...
Evolutionary convergence of a Pyroptosis-Apoptosis crosstalk drives non-canonical inflammasome signalling.
The coordination of efficient immune responses to infections is essential to enable pathogen clearance and host survival. Cell death modalities are a crucial component of the innate immune system and ...
biorxiv.org
Interested in joining the Powrie Lab? We’re looking for a Postdoctoral Researcher to study the neutralisation capacity of human anti-IL-10 autoantibodies. You’ll be part of our new MRC CoRE in Exposome Immunology!🧫🦠 Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...
bulletin.ndorms.ox.ac.uk
🔔 Chech out this new cool story on non-canonical inflammasome signaling in NK cells by @protinnimmunity.bsky.social
Non-canonical inflammasome drives intrinsic anti-microbial responses in human Natural Killer (NK) cells. https://www.biorxiv.org/content/10.1101/2025.10.20.682800v1
SAVE THE DATE! The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast. Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions. Follow us to stay tuned! www.ukcellmicro.org
The second day of the @dib-unil.bsky.social #PRR symposium kicks off with more excellent talks including our own Jakub Began.
📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵 biorxiv.org/content/10.1...
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
currentprotocols.onlinelibrary.wiley.com
Ready to start 2 days of everything innate immunity and inflammation #bsiinflammation2025 @britsocimm.bsky.social
Looking for passionate candidate to apply to PhD fellowship to University of Murcia call: www.um.es/documents/d/... Interested students contact me!
um.es
#MycobiotaPower! Exciting work @nature.com by Behnsen, Jaswal &co showing that #Salmonella uses type 3 secretion system to hijack #Candida_albicans to produce arginine in the gut, boosting Salmonella infectivity & reducing the immune response! www.nature.com/articles/s41...
Commensal yeast promotes Salmonella Typhimurium virulence - Nature
Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.
nature.com
So excited that this study is now online! It's been a pleasure to work with BioAge Labs and our collaborators on this story. We characterise a new class of #NLRP3 inhibitors with translational potential for so many inflammatory diseases.
#NLRP3 is a target for antiinflammatory therapies & can be inhibited by the tool compound MCC950. Wilhelmsen, @colllab.bsky.social et al characterize new small-molecule inhibitors, BAL-0028 & BAL-0598, that have a distinct mechanism of action & binding site. rupress.org/jem/article/... #Inflammasome
Still time to register for the BSI inflammation meeting 2025! Don’t miss out on this fantastic meeting !.
🔥 Last call! Today’s the FINAL day to submit your abstract for “Innate immunity & inflammation: UK inflammation 2025.” Don’t miss your chance to get involved! Submit now and join leading experts this September in Manchester. Event & submission info: bit.ly/43q9x9r
10 things you wish you knew about inflammatory caspases: a holistic review of their biochemistry, activation, and signalling - Journal of Biological Chemistry www.jbc.org/article/S002...
10 things you wish you knew about inflammatory caspases: a holistic review of their biochemistry, activation, and signalling
Caspases are a family of cysteine proteases conserved across all multicellular life which play critical functions that range from cell death, inflammation and cellular differentiation. Caspases cleave...
jbc.org
(1/3) We've been catching up with our GenerationResearch students so far this summer..! "Hi, I am Naomi, a Biomedical Sciences student going into the final year of my Integrated Masters at York. I am currently doing my Generation Research studentship in Dave Boucher's Lab.
🔥 Last call! Today’s the FINAL day to submit your abstract for “Innate immunity & inflammation: UK inflammation 2025.” Don’t miss your chance to get involved! Submit now and join leading experts this September in Manchester. Event & submission info: bit.ly/43q9x9r
Still time to register to the next BSI Innate Immunity and Inflammation meeting. Join us for 2 days packed with great science and networking opportunities!
Interested in innate immunity and inflammation? Join us in September for a great meeting! Superb lineup of speaker and lots of opportunities for Ecrs to present!
Still time to register to the next BSI Innate Immunity and Inflammation meeting. Join us for 2 days packed with great science and networking opportunities!
Interested in innate immunity and inflammation? Join us in September for a great meeting! Superb lineup of speaker and lots of opportunities for Ecrs to present!
Congratulations to the winner of the 2025 BSI Outstanding Leadership Award, sponsored by @ceijournal.bsky.social … Professor Clare Bryant, @clarebryant.bsky.social
Interested in innate immunity and inflammation? Join us in September for a great meeting! Superb lineup of speaker and lots of opportunities for Ecrs to present!
Dive into cutting-edge innate immunity & inflammation science at our event on September 11! From immune cell roles to inflammasome signalling, discover advances shaping clinical care. 📆Abstract deadline: 15 July 🐦Early bird registration ends: 27 August 🔗 bit.ly/43q9x9r
Interested in #InnateImmunity ? Register now to secure your spot — abstracts can be submitted later! More info: wp.unil.ch/immunobiolog... #ImmunoSky
Symposium immunobiology
wp.unil.ch
🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!
Great work by the @inflammasomelab.bsky.social @s-burgener.bsky.social and colleagues showing in vivo the importance of caspase-1 inactivation in controlling inflammation! Impressive amount of work behind it, glad to see this out! www.biorxiv.org/content/10.1...
Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseases
Signal shutdown mechanisms must exist to silence the potent inflammatory programs initiated by the caspase-1 (CASP1) protease, to allow inflammation to resolve and reinstate tissue homeostasis. It is ...
biorxiv.org
We have a 3-year PDRA post in Cancer Immunogenomics. Ideal to use and strengthen your bioinformatics skills to discover how cancer transcriptome quirks shape immunotherapy outcomes. Funded by @cancerresearchuk.org. It’ll be fun! jobs.york.ac.uk/vacancy/rese... @hyms.ac.uk @ybri-uoy.bsky.social
Jobs - The University of York
jobs.york.ac.uk
🔥 Open postdoc position in human inflammation-driven control of infection! 🔥 Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5) Please share!