Lab Lunch: English Edition! Advanced English language with #TheStreets Fit but you know it 🎶 and a trifle to fuel the afternoon's work
Alison Forrester
@aforrester.bsky.social
A fan of ER and derivatives thereof, I’m a microscopic cell biologist. PI at University of Namur in Belgium
🚨🚨Last day to register for the next annual meeting of Club Exocytose-Endocytose !!!🚨🚨 Invited speakers: M. Stroeber, G. D'Angelo and @christlet.bsky.social 📍 Centre Paul-Langevin, Aussois, France 📅 May 27–29, 2026 Get ready for exciting science!! Registration here exoendo.org/evenement/28...
28ème congrès du Club Exo Endo - Aussois (Savoie)
Speakers invités: Giovanni D’Angelo (EPFL, Lausanne, Suisse) Christophe Leterrier (INP, Marseille, France) Miriam Stoeber (University of Geneva, Genève, Suisse)
exoendo.org
That time of the year again. The @szndohrn.bsky.social 2026 call for the Open University-SZN PhD program is open. 5 projects available (one of which is in my lab). Application deadline is the May 21st. Link to the call: www.szn.it/index.php/it... and the flyer of the project in my lab
The application deadline for the 20th FEBS/EMBO Spetses meeting is extended to the 15th March! Please sign up at the link below, or encourage your PhDs and postdocs to come along for what is certain to be a wonderful week!
CALLING PHDs AND POSTDOCS! Apply for the 20th FEBS/EMBO summer school on Membranes lipids & proteins in organelle biogenesis! Spend a glorious week with leaders in the field on the beautiful island of Spetses in Greece this May. Registration: spetses2026.sites.uu.nl @embo.org @febspress.bsky.social
A study on the effect of being a PI on greying hair. Correlation or causation? (Also an article on the Roadmap published last year in NRMCB) www.unamur.be/en/newsroom/...
A multidisciplinary framework for protein trafficking: tackling unanswered questions
unamur.be
CALLING PHDs AND POSTDOCS! Apply for the 20th FEBS/EMBO summer school on Membranes lipids & proteins in organelle biogenesis! Spend a glorious week with leaders in the field on the beautiful island of Spetses in Greece this May. Registration: spetses2026.sites.uu.nl @embo.org @febspress.bsky.social
𝙈𝙚𝙢𝙗𝙧𝙖𝙣𝙚𝙨 𝙖𝙣𝙙 𝙩𝙝𝙚𝙞𝙧 𝙡𝙞𝙥𝙞𝙙𝙨 𝙖𝙣𝙙 𝙥𝙧𝙤𝙩𝙚𝙞𝙣𝙨 𝙞𝙣 𝙤𝙧𝙜𝙖𝙣𝙚𝙡𝙡𝙚 𝙗𝙞𝙤𝙜𝙚𝙣𝙚𝙨𝙞𝙨 - Spetses, Greece - May 2026 | Utrecht University
Utrecht University
spetses2026.sites.uu.nl
I'm very happy to have been involved in this roadmap. Thank you all for the fantastic discussions, I hope that it initiates many more!
ER exit sites are dynamic ER subdomains that integrate signals, reshape membranes and steer secretion. Twelve groups in the field came together to map their diversity, regulation, unanswered questions and future directions. www.nature.com/articles/s41...
Dear all, I have coined a phrase: To A.Iron Definition: To polish text using AI @academic-chatter.bsky.social
📄Shoutout to our 2019 Research Center awardees at Yale (@pdc-lab.bsky.social, @shawnferguson.bsky.social) for their new publication on the bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage: www.nature.com/articles/s41...
The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage - Nature Cell Biology
Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal damage.
nature.com
For clear thinking, cultivate passionate indifference. Buddhists call it non-attachment. We all have hopes, desires and ambitions. Non-attachment means acknowledging them, accepting them, and then not inserting them into a process that has nothing to do with you. podcasts.apple.com/us/podcast/n...
Congrats to the Johannes lab! 👏 E MacDonald, @aforrester.bsky.social @cessvala.bsky.social E Dransart, A Akhil Shp, L Leconte, V Chambon, D Ghosh, A Pinet, D Bhatia, B Lombard, D Loew, MShafaq-Zadah, @christianwunder.bsky.social @institutcurie.bsky.social pubmed.ncbi.nlm.nih.gov/39984654/
Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis - PubMed
Glycolipid-lectin-driven endocytosis controls the formation of clathrin-independent carriers and the internalization of various cargos such as β1 integrin. Whether this process is regulated in a dynam...
pubmed.ncbi.nlm.nih.gov
📣 We are advertising for a postdoc to join our team at the University of Edinburgh! Our lab studies gene regulatory mechanisms in development, and how genetic changes may impact these processes to alter development and shape human craniofacial form and function 🧬🧪
Postdoctoral Researcher
Our research is focused on understanding how genetic changes in the non-coding genome can impact gene regulatory mechanisms, alter developmental processes and ultimately affect human craniofacial shap...
elxw.fa.em3.oraclecloud.com
The 16th ER & Redox club meeting ends. THANK YOU to co-organiser @fenech-lab.bsky.social & to everyone for outstanding presentations, discussions, posters and fun over the last 4 days in Namur. Huge thanks to @unamur.bsky.social @biologists.bsky.social @febspress.bsky.social for support and funding!
A terrific perspective from Vivek Malhotra @naturecomms.bsky.social on the fundamental importance of pathways and mechanisms by which cells secrete proteins, ensuring their delivery in the correct quantities and at the appropriate times. Interesting section on unanswered questions. rdcu.be/ecb2B
The pathways of secretory cargo export at the endoplasmic reticulum
Nature Communications - The author presents an overview of the complex challenge of protein export from the Endoplasmic Reticulum, and discusses how cells may deploy novel pathways utilizing...
rdcu.be
journals.biologists.com/jcs/article/...
The importance of delivering Recherche d'Avenir – research for the future
In recent years, several European countries, including France, have reduced their investment in scientific research, with biomedical research taking a significant hit. The primary casualty is basic re...
journals.biologists.com
Lab manager position open. Does the idea of helping a busy structural cell biology and biochemistry-based drug discovery lab stave off chaos appeal to you? Apply now at tinyurl.com/4dsvpwbw
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tinyurl.com
Just a week left to apply for this postdoc position in my lab in Oxford.
I'm happy to announce a postdoctoral position is available in my lab. We have lots of great data to analyze with respect to transposons & epigenetics and cool biological questions to answer. Please reskeet and share.
... and soon the structural glycoswitch: www.biorxiv.org/content/10.1...
Spatial N-glycan rearrangement on α5β1 integrin nucleates galectin-3 oligomers to determine endocytic fate
Membrane glycoproteins frequently adopt different conformations when altering between active and inactive states. Here, we discover a molecular switch that exploits dynamic spatial rearrangements of N...
biorxiv.org
I'm thrilled that our paper is now online: www.nature.com/articles/s41... describing an elegant pH-triggered CIE. Thanks to everyone who made it an exciting and successful project @ewanmacdonald.bsky.social @cessvala.bsky.social @christianwunder.bsky.social #fluorescencefriday #microscopymonday
Growth factors trigger receptor desialylation at the plasma membrane, galectin binding and subsequent endocytosis. => A proton pump driven glycoswitch @naturecellbiology.bsky.social : rdcu.be/eaLM9 #glycotime, @institutcurie.bsky.social, @cnrs.fr, @inserm.fr, #NIH, #CellBiol, #Cancer
I'm happy to share our review latest review on flotillins! We discuss the recent insights into the structure of these interesting proteins from cyro-EM studies. doi.org/10.1111/boc....
Flotillins in membrane trafficking and physiopathology
Flotillin 1 and 2 scaffold sphingolipid-rich membrane microdomains involved in endocytosis and endolysosome maturation through the generation of sphingosine 1-phosphate (S1P) by sphingosine kinase 2...
doi.org
Going Green at the Department of Biology and Faculty of Medicine at the University of Namur! We've worked on it for a year, now it's time to go big 😁💚🔬 The initiative seems to be making some waves and it's great to see som much enthusiasm! @fsilvestrelab.bsky.social #sustainability #GreenLab
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy www.biorxiv.org/content/10.1...
Inscriptions for the 27th annual meeting of the Club Exo-Endo are opened. Please register on exoendo.org !!
Check it out, powerful new method for optical imaging of the live ECM, from @hhmijanelia.bsky.social Group Leader Kayvon Pedram #proudofalumni #glycotime www.nature.com/articles/s41...
Live imaging of the extracellular matrix with a glycan-binding fluorophore - Nature Methods
Rhobo6 is a cell-impermeable small-molecule fluorophore that displays reversible fluorogenic binding to glycans, making it a general, wash-free, and non-perturbative label for the extracellular matrix...
nature.com
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that. www.biorxiv.org/content/10.1...
Our plasmids for editing are now on @addgene.bsky.social! www.addgene.org/Francesca_Bo... I promise you a detailed protocol on how to use them is coming very very soon! Currently proofreading :)
Addgene: Francesca Bottanelli Lab Materials
addgene.org
Excited to see work led by @autophazeke.bsky.social, @minghaochen.bsky.social, Thanh Nguyen, and Ainara Claveras out in @science.org today, the culmination of a 15-year project to understand structurally how the synthesis of the critical lipid of autophagy, PI3P, is regulated. tinyurl.com/ywvjh8u4
We're happy to announce the launch of the new website of the Club Exo-endo. From the site, you can register for the annual meeting, register as a new member, advertise a position, apply for the thesis prize or post your latest publication. Please visit us at exoendo.org and make it interactive !
Club Exo Endo - Exocytose Endocytose
Le Club Exocytose-Endocytose est une association à but non lucratif, sans financement ni cotisation. Il rassemble près de 340 chercheurs, enseignants ou étudiants travaillant dans des domaines variés ...
exoendo.org
The #MembraneTrafficking seminar series is back this Thursday, and we are very happy to start the 2025 season with two talks by early career scientists: Adam Krahn from the Glick Lab at University of Chicago and @jkefauver.bsky.social at CINN-CSIC, Spain.
MEMBRANE TRAFFICKING | Membrane Trafficking
felixcampelo.wixsite.com
Just wrapped up an incredible meeting in Innsbruck with an amazing group of membrane traffickERs. The intimate, congenial setting fostered open, positive discussions and constructive critiques—intense and inspiring. Huge thanks to Hesso @hessofarhan.bsky.social for organising!
The first sermon!