Erik Van Dis

@erikvandis.bsky.social

Immunologist and Damon Runyon fellow in the Stetson lab at UW, interested in innate immunity and cell death. Previously at Berkeley, Carleton College and Rocky Mountain Labs

I wrote about a reason not to use generative AI in your writing that I haven't seen anyone talking about. Once I realized this, banning GenAI in our lab's writing became a no-brainer. Feel free to share, I think this is probably useful especially for trainees: www.carlsonlab.bio/thoughts/the...

The only reason you’ll ever need not to write with AI — The Carlson Lab

Over the last year, our lab has been developing a policy on AI use. To do this, we did three main things: We read a lot of academic publications and tech news. We set up an #ai channel on our la...

carlsonlab.bio

Incredibly, mice with ablated VPGABA neurons (red line) completely failed to gain weight on high-fat diet. Normal control mice are in gray. By turning off over-eating outside of caloric need, we blocked obesity in mice.

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Dr. Marc K. Jenkins is a scientific hero for so many of us. And just a man who loves to sing Johnny Cash for some. Please join us in celebrating his extraordinary career with a retirement symposium at the University of Minnesota on Monday, September 14th! 🎉 To learn more see link in post below👇:

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SCOOP: Two weeks ago, the head of the CDC delayed publication of a report showing covid vaccine cut likelihood of ER visits and hospitalizations by half. Now that report is no longer allowed to be published in CDC’s flagship scientific journal. My latest. 1/2 www.washingtonpost.com/health/2026/...

CDC won’t publish report showing covid shots cut likelihood of hospital visits

The report, which had cleared the agency’s scientific-review process, had been delayed. It now won’t be published at all, people familiar with the decision told The Post.

washingtonpost.com

The number of NIH competitive awards is down 50% from 2025, and down ~70% from prior years. Even if they catch up by the end of the year, only wealthy institutions can bridge these huge funding gaps.They're killing science-and violating the constitution-by weaponizing the bureaucracy

figure showing the trends I detail in the tweet text
The Washington Post@washingtonpost.com · 4mo ago

Through March 31, the number of grants awarded by the National Institutes of Health is down by more than half compared with the same period last year, a Post analysis found. There are also fewer grants focused on women’s health, cancer and mental health, the analysis found. https://wapo.st/48dWJWX

And finally: K grants These support post-docs and early career researchers. Landing one of these can be your ticket to a tenure track gig. They're career-makers. # of new grants issued through April 15 in FY2024 (the last “normal” year): 374 FY2025: 252 FY2026: 140

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American science is shrinking. 
A Post analysis found that, halfway through this fiscal year, the number of competitive grants awarded by the National Institutes of Health is down by more than half compared with the same period last year. https://wapo.st/3OgoHKV

For U.S. medical researchers, shrinking labs and bare budgets are the new reality

The Trump administration has slashed the number of grants from the National Institutes of Health, with far fewer focused on women, cancer and mental health.

washingtonpost.com

The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.

Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302

Thrilled to share our new preprint showing that dietary amino acids license the NLRP3 inflammasome via mTOR-dependent mRNA translation! Congrats to co-1st authors @mikelhaggadone.bsky.social, Brian Goldspiel, co-senior author @metabailism.bsky.social & collaborators! www.biorxiv.org/content/10.6...

biorxiv.org

Mikel Haggadone, PhD@mikelhaggadone.bsky.social · 7mo ago

I’m stoked to share my postdoc work with @sunnyshinlab.bsky.social, a collaborative effort with @metabailism.bsky.social & Brian Goldspiel, aided by many valued collaborators: Environmental Amino Acid Sensing Regulates the Rate of ASC Translation and NLRP3 Inflammasome Assembly. Some big takeaways: