🚨New preprint doi.org/10.64898/2026.06.07.730682. We show that zebrafish larvae exhibit complex, internally generated, spontaneous behavioral patterns in the absence of stimuli. These dynamics can be described by a simple Markov process with transition probabilities that change over time.
Oded Mayseless
@mayseless.bsky.social
Postdoc in the @schierlab. Visiting scientist @RainerFriedri12. PhD @lab_oren @WeizmannScience. What is the molecular basis of good vs evil? #zebrafish #olfaction
Yet another #zebrafish genome update: We just updated our ZebrafishGenomics public datahub for the UCSC browser (available all the way at the bottom here: genome.ucsc.edu/cgi-bin/hgHu...). We added several useful tracks including:
genome.ucsc.edu
Finally out in @natneuro.nature.com! A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work! www.nature.com/articles/s41...
Creating true and false memories from forgotten information in Drosophila - Nature Neuroscience
Forgotten memories in Drosophila persist as silent memory traces and can be recovered by reminder cues. Manipulating reminders can create false memories, showing that memory reconstruction flexibly in...
nature.com
🧠 A new paper from our lab is out! In this study, we explore how dorsal raphe nucleus (DRN) circuits modulate forebrain activity and behavior. www.nature.com/articles/s41...
Topographically organized dorsal raphe activity modulates forebrain sensory-motor representations and contributes to defensive behaviors - Nature Communications
Functional heterogeneity of dorsal raphe nucleus is not fully understood. Here authors show topographically organized sensory and locomotor responses from the zebrafish dorsal raphe and its forebrain ...
nature.com
We're excited to present a single-cell atlas of vertebrate cranial motor neuron development, the first story from my postdoctoral work in the Moens lab, up now on bioRxiv!
We have an open professor position at my institute, the Institute for Quantitative Biosciences, The University of Tokyo! www.iqb.u-tokyo.ac.jp/recruiting/2...
iqb.u-tokyo.ac.jp
🚨 New Preprint! 🚨: A new method for quantifying #tissue #clearing and a next-get #lightsheet #Microscope - the #mesoSPIM ultra by Marko Pende, @jcregg.bsky.social, @murawalalab.bsky.social @mdibl.org & many more! Preprint: www.biorxiv.org/content/10.6... Github: github.com/mesoSPIM/mes...
We are excited to share our collaboration with @pheereynolds.bsky.social, Robert Hindges & team on retinal plasticity, now out in Neuron! This work shows how visual experience during early development changes the anatomical and functional properties of amacrine cells and ultimately behavior!
Early visual experience elicits cellular and functional plasticity in the retina and alters behavior
The understanding of experience-dependent plasticity in the vertebrate retina is largely incomplete. Reynolds et al. discovered that raising animals in differently patterned visual environments change...
cell.com
I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...
science.org
Out now in @science.org by @emreyaksi.bsky.social, Anh-Tuan Trinh and colleagues at the Kavli Institute in Trondheim: Hierarchical sensory processing in zebrafish thalamocortical-like circuits doi.org/10.1126/scie...
Happy to share our new paper published in @currentbiology.bsky.social! Using in vivo imaging of genetically defined zebrafish retinal ganglion cells (RGCs), we show that while some Satb2+ RGCs maintain stable functional identities during development, others undergo functional changes.
My department, Neurobiology and Biophysics at the University of Washington (nbio.uw.edu), is hiring a new tenure-track Assistant Professor, application deadline 09/30/26. It's a broad search — molecular to organismal, all of neuroscience/physiology/biophysics welcome. apply.interfolio.com/187735
1/ 🧬🔬 How does one cell become an entire animal? We can now film it in 3D 🐟, but turning those movies into accurate cell tracks is brutally hard. Enter our new #Kaggle challenge: $60K prize pool, to help crack 3D+time cell tracking at scale! 🧵👇 www.kaggle.com/competitions... @biohub.org
Very excited to finally share my PhD! 🎉 Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances. Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social! 📄 www.science.org/doi/10.1126/...
Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish
Loss of the conserved splicing factor for neuronal microexons disrupts neuromodulatory signaling and drives hyperarousal.
science.org
We're hiring! The Department of Life Sciences at Imperial College London is seeking a new Assistant Professor in ecology, evolution, or environmental science. It's a great department with great students at a great university. www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
imperial.ac.uk
I’m very excited to share that our paper is now out in Neuron! 🎉
New paper out: www.cell.com/iscience/ful... Congratulations to our former PhD student @maxcapelle.bsky.social whose work reveals that the switch in light preference across zebrafish development is driven by a reweighting of three parallel visual processing pathways. Check out a short summary below!
We are proud to have @maxcapelle.bsky.social's paper out on bioRxiv! He found that phototactic behavior in #zebrafish switches during #ontogeny🐟🔆 Through elegant behavioral dissections, he identifies the navigational strategies related to this transition. www.biorxiv.org/content/10.1... Thread 👇
Might cerebellar disinhibition underlie Restless Legs Syndrome symptoms? Will Joo found that loss of the RLS-associated gene meis1b perturbs locomotion in zebrafish by disinhibiting cerebellar output. www.sciencedirect.com/science/arti...
Congratulations! This was long in the making and the resulting data is quite beautiful. Definitely worth a read!
1/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
🔗 to paper: www.biorxiv.org/content/10.6...
1/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
Happy to have contributed to this mastodon of a paper about how the nose knows 🧪🐟
1/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
1/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪
biorxiv.org
Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis
Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...
science.org
1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here: rdcu.be/eX1L4
Plastic landmark anchoring in zebrafish compass neurons
Nature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.
rdcu.be
Very proud to see our paper selected as one of Nature’s 2025 highlights! @johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social www.nature.com/articles/d41...
Asteroids, antibiotics and ants: a year of remarkable science
Highlights from News & Views published in 2025.
nature.com
“Up ’till now, we couldn’t detect it, because we didn’t look at the garbage cans of cells.” Yifat Merbl found a new trick of the immune system, and is part of Nature’s 10, a list of people who shaped science in 2025 go.nature.com/3XQWoUt
This scientist found a new trick of the immune system by digging through cellular rubbish
Yifat Merbl is part of Nature’s 10, a list of people who shaped science in 2025.
go.nature.com
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus - Nature Communications
How are various visual signals integrated in the vertebrate brain for navigation? Here authors show that different spatial signals are topographically organized and align to one another in the zebrafi...
nature.com
Very excited to share this thread on our recent paper! We show how Zebrafish integrate visual navigation signals in aligned topographic maps. Full thread below🧵
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv: www.biorxiv.org/content/10.1...
biorxiv.org
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp