NiceLab

@nicelab.bsky.social

We study antiviral immune responses of the intestinal epithelium, especially interferon lambda. We focus on how they are specialized for the gut, interactions with normal microbiota at homeostasis, and how they may go awry during inflammatory diseases.

💐 To NIH and NSF program officers, and anyone else trying to keep those institutions alive: Thank you for trying to do an impossible job in an impossible time. I’m sorry for all of us that this is the world we’re living in. 1/n

Jeremy Berg@jeremymberg.bsky.social · last yr.

Just before bedtime last night I got a message from inside NIH which read: “It’s so, so bad and no one cares (who has any influence)” I asked “What, in particular?” My friend responded “Everything”

Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/... Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n

Rewilding catalyzes maturation of the humoral immune system

Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.

science.org

NEW: In every way, shape, form, actions being taken say ‘don’t go into science,’ Donna Ginther told me as NIH forced to cancel programs to train future researchers. More than 1,000 students, including one who emailed 60 PIs, now scrambling to find positions. www.statnews.com/2025/03/05/t...

Cancellation of NIH summer internships disrupts ‘vital’ training program for U.S. scientists

The NIH cancelled an internship program that gave more than 1,000 college students hands-on research training each summer

statnews.com

First post on Bluesky! Excited to share the first paper from our lab in 2025! cell.com/cell-host-mi.... Our study demonstrates that UV-inactivated replication-defective rotaviruses can cause diarrhea in neonatal mice, suggesting the host response also contributes to diarrhea to flush out the virus.

Innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea

Hou et al. demonstrate in an infant mouse model that innate immune sensing of enteric viruses induces IFN-λ signaling, which downregulates an apical chloride exchanger that leads to increased intestin...

cell.com

No new NIH study sections have been announced in the Federal Register since Jan 21. But I hear that colleagues have been asked to serve. Does your meeting appear in these announcements? If this applies to you, please check and reply here with info! www.federalregister.gov/documents/se...

Document Search Results for 'center for scientific review'

Search, browse and learn about the Federal Register. Federal Register 2.0 is the unofficial daily publication for rules, proposed rules, and notices of Federal agencies and organizations, as well as e...

federalregister.gov