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Taia Wang Laboratory

@wanglaboratory.bsky.social

How antibodies orchestrate the immune response. https://www.taiawanglaboratory.com/

38 Posts3019 Follower1631 Folgt
Immunity@cp-immunity.bsky.social · 3mo ago

Online now: Pharmacologic glycoengineering of Fcγ receptor IIIa enhances force-resistant IgG-FcγR interactions and anti-tumor antibody efficacy

Pharmacologic glycoengineering of Fcγ receptor IIIa enhances force-resistant IgG-FcγR interactions and anti-tumor antibody efficacy

Therapeutic monoclonal antibodies are central to cancer treatment but often show incomplete efficacy. Cheng et al. demonstrate that transient host-cell glycoengineering to reduce N-glycan trimming strengthens IgG-FcγRIIIa bond resilience under vascular flow forces and potentiates therapeutic antibody efficacy in lymphoma and melanoma models. This study establishes force durability as an optimization parameter for therapeutic antibodies beyond the affinity-centric paradigm.

dlvr.it

Sarah Cobey@cobey.bsky.social · last yr.

I received a surprising and disturbing request from NIH on Friday. They wrote to cancel a subaward to Hong Kong on one of my grants. (This was disturbing but not surprising.) They also ordered us not to interact with our collaborators in Hong Kong on any work under the award:

Screenshot of email stating "The subaward and the associated amounts listed above will need to be removed from the current and future year awards, and any other amounts budgeted for activities related to the Hong Kong research must also be removed. No rebudgeting of these funds is permitted, and no involvement or collaboration with researchers in Hong Kong or China is permitted in connection with the activities of this award, regardless of whether any funds are transferred," with the "no involvement" clause highlighted.
public health guy@publichealthguy1.bsky.social · 3mo ago

nancy cox was a true public health hero. a brilliant and dedicated civil servant who worked diligently for decades to protect the public's health. she saved a lot of lives, and did so in the background

Helen Branswell 🇨🇦@helenbranswell.bsky.social · 3mo ago

The world of influenza science has lost one of its giants. Nancy Cox, who led #CDC's flu division for years & worked assiduously to improve global flu surveillance, died Thursday. I learned a ton from Nancy Cox. RIP. www.statnews.com/2026/04/25/n...

Marion Pepper@marionpepper.bsky.social · 10mo ago

Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here: www.biorxiv.org/content/10.1...

Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells

Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...

biorxiv.org

Taia Wang Laboratory@wanglaboratory.bsky.social · last yr.

Assistant professors studying immunity to infectious disease - don’t miss this opportunity! The BWF PATH program supports innovative research on molecular and/or systemic mechanisms that influence outcomes of pathogen exposure. @bwfund.bsky.social Learn more & apply: www.bwfund.org/funding-oppo...

Investigators in the Pathogenesis of Infectious Disease - Burroughs Wellcome Fund

bwfund.org

Burroughs Wellcome Fund@bwfund.bsky.social · last yr.

Announcing the 2025 Investigators in the Pathogenesis of Infectious Disease www.bwfund.org/news/announc... #bwfpath

Jake Janey@phlogiston1.bsky.social · last yr.

An amazing opportunities on my team at #VertexPharmaceuticals I’m looking for a Director in Chemistry Technology for research and preclinical #Chemsky #Chemistry #IT #Data www.linkedin.com/jobs/view/42... coming soon is another director level role in #HPC and data @chemjobber.bsky.social

Vertex Pharmaceuticals hiring Director, Chemistry Technology in Boston, MA | LinkedIn

Posted 5:52:23 PM. Job DescriptionGeneral Summary:Vertex is a global biotechnology company that invests in scientific…See this and similar jobs on LinkedIn.

linkedin.com

@LaBonneLaB@labonnelab.bsky.social · last yr.

Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post. www.washingtonpost.com/opinions/202...

Opinion | Universities and the government: Which needs the other more?

From public health to high-tech innovation, universities are the workhorses of national progress.

washingtonpost.com

Peter Gleick@petergleick.bsky.social · last yr.

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

Graphs showing 25 years of budgets for the National Institute of Health, NASA, and the NSF. In all cases, the proposed budget for next year is far, far below any year of the previous quarter century.