Jonny Nixon-Abell
@abelljonny.bsky.social
Group Leader @TheCIMR. Organelle Interactions and dynamics in neurons. Wellcome CDA Fellow. prev: @NIH, @UCL, @HHMIJanelia. 🧠+🔬 (AbellJonny on X) https://www.cimr.cam.ac.uk/staff/dr-jonathon-nixon-abell
www.biorxiv.org/content/10.6...
Ire1 membrane stress responses support cell growth upon disruptions in inter-organelle contacts
Disruptions in inter-organelle contacts result in membrane lipid homeostasis defects that ultimately impair cellular function and viability. Yet, essential responses to membrane lipid imbalances remai...
biorxiv.org
Job alert! I'm recruiting a new post-doc to work on mechanisms of co-translational quality control in the ER. Looking for expertise in ribosome biology and yeast genetics/cell biology. Please reach out to me with any questions. www.dundee.ac.uk/work-for-us/...
Postdoctoral Research Assistant - UOD2336
Closing date: Thursday 27 August 2026, 23:59
dundee.ac.uk
🚨🚨Final reminder for abstract submission deadline next Tuesday (28th)! Please RT 🙏
Jonny Nixon-Abell@abelljonny.bsky.social · 7mo ago‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏
🚀🔬 Can cell shape, signal and movement tell us about a cell's future? #DeepLearning studies now predict cell fate from #microscopy. Together w Rita, @mariodelr.bsky.social, @inesmcunha.bsky.social, @juliettegriffie.bsky.social + @guijacquemet.bsky.social👇 www.preprints.org/manuscript/202607.1414/v1
Reminder all that the deadline for sign up and abstract submissions is July 28th!!
Jonny Nixon-Abell@abelljonny.bsky.social · 7mo ago‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏
Exciting preprint from @hessofarhan.bsky.social! Mechanical stress has a new sensor! IRE1 detects ER membrane tension and drives protein synthesis independently of its canonical UPR role, reshaping cell and organelle mechanobiology. www.researchsquare.com/article/rs-1...
Mechanosensing at the endoplasmic reticulum by IRE1
Sensing and integration of mechanical forces in eukaryotic cells have largely been attributed to the plasma membrane and the nucleus. Here, we identify the endoplasmic reticulum (ER) as an autonomous ...
researchsquare.com
Last chance to apply for Associate or Senior Editor in Neuroscience and Regenerative Medicine for Science magazine @science.org jobs.sciencecareers.org/job/679035/a...
Associate or Senior Editor - Washington D.C., Cambridge, UK job with American Association for the Advancement of Science | 679035
Join the editorial team at Science! We are seeking a full time Associate or Senior Editor
jobs.sciencecareers.org
Thrilled to share this #lipidtime mechanism story in @jcb.org where, led by Shiying Huang and in collaboration with Tamas Balla’s lab, we uncover plasticity in phospholipid metabolism to preserve plasma membrane identity and integrity in the face of disease-relevant perturbations!
Journal of Cell Biology@jcb.org · last mo.How does the plasma #membrane preserve its #lipid identity under stress? The Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. rupress.org/jcb/article/... @jeremybaskin.bsky.social
Great collaboration with @adrianisaacs.bsky.social showing coordinated role for FTD/ALS proteins CHMP2B and ANXA11 in membrane repair! Well done Catherine Heffner, Georgina Starling, Lorian Cobra Straker and Pippa Hawes! @crick.ac.uk, @ukdri.ac.uk, @kingslsm.bsky.social. www.cell.com/developmenta...
The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair
Heffner et al. show that ANXA11 and CHMP2B, proteins encoded by ALS- and FTD-risk genes, are sequentially recruited to sites of plasma membrane damage. Membrane repair involves ANXA11-positive plug fo...
cell.com
Your periodic reminder that the non-profit publisher @biologists.bsky.social funds grants that support meetings in the areas of its journals: @jcellsci.bsky.social @dev-journal.bsky.social @jexpbiol.bsky.social @dmmjournal.bsky.social 1/2 🧪 www.biologists.com/grants/scien...
Scientific Meeting Grants
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
biologists.com
This amazing work by @danialv.bsky.social and Bodan Hu is now out in peer-reviewed form at @cp-cell.bsky.social with a lot of new simulations! Check it out if interested in lipid transport!
Vanni Lab at UNIFR, Switzerland@labvanni.bsky.social · 7mo agoHappy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7) www.biorxiv.org/content/10.6...
Today is bittersweet as we have to say goodbye to the amazingly talented Priyanka Peres. Our first lab alumni who will be going on to do her PhD as a Clarendon Scholar at Oxford. Huge congrats Priyanka - you will do great things and will be sorely missed @thecimr.bsky.social 🙏
Great opportunity for those looking for a PhD in synaptic biology and A-syn!
lautenschlagerlab.bsky.social@lautenschlagerlab.bsky.social · 2mo ago👉 Fully Funded PhD (UK Students Only) 👈 I'm recruiting a PhD student to join my lab at UCL to investigate how alpha-synuclein condensates contribute to synaptic dysfunction in Parkinson’s, for details: www.findaphd.com/phds/project... #PhD #Neuroscience #Parkinson @ucl.ac.uk @uclnpp.bsky.social
☕ @dr-downes.bsky.social et al. use in situ cryo-electron tomography and super-resolution fluorescence microscopy to define ER exit site architecture in unperturbed human cells. They visualize ribosome-exclusion zones enriched with COPII- and COPI-coated vesicles. bit.ly/3RGH6lp
In situ cryo-ET defines the ultrastructure of ER exit sites in human cells - Nature Cell Biology
Downes et al. use in situ cryo-electron tomography and super-resolution fluorescence microscopy to define ER exit site architecture in unperturbed human cells. They visualize ribosome-exclusion zones ...
bit.ly
Wow! It was not simple, but we managed to package and ship 3 confocal microscopes from @thecimr.bsky.social to the Sena Institute of Technology in Penyi, Ghana. A massive thanks to all the amazing people at CIMR who helped out, and can’t wait to see these scopes running and producing data at SIT!
Really looking forward to this and can’t wait to visit @livuni-ismib.bsky.social !!
Molecular & Clinical Cancer Medicine (MCCM)@livunicancer.bsky.social · 2mo agoOur NWCR-sponsored seminar this Tuesday 2nd June, 1-2pm! All invited! @livuni-ismib.bsky.social "Understanding organelle contact sites in neuronal health and disease" Guest @abelljonny.bsky.social Host @drlornayoung.bsky.social
Guess what neurobiology fans?!? Registration is open!! More info on the website neurobiouk.sites.sheffield.ac.uk/registration #neurobiology #neurobiouk #neuronalcellbiology #molecularneurobiology #cellularneuroscience #neuroscience
NeuroBioUK - Registration
Step 1: Register through our event page. All attendees should register to attend through our event page. Early bird registration deadline is the 17th of July (£35) and late registration deadline is th...
neurobiouk.sites.sheffield.ac.uk
Ali Twelvetrees @dozenoaks.bsky.social · 5mo agoSave the date for #NeuroBioUK26 Do you like neurons? Maybe glia? Molecules? Cell biology? - The venue is booked and we are excited to see you and your incredible science there on the 11th of September! Please do join our email list to stay up to date. neurobiouk.sites.sheffield.ac.uk
That’s a wrap for #JCSimaging, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti. Thanks to everyone who joined us and made the conference such a wonderful community event. journals.biologists.com/jcs
Could we boost the nervous system's ability to repair damaged brain cells?🔬 New research by Dr Jobert Vargas and Prof Giampetro Schiavo (UK DRI at UCL) in collaboration with Dr Andrea Serio (UK DRI at King’s), uncovers key insight into how human neurons can be repaired. ukdri.ac.uk/news-and-eve...
The Canadian Association for Neuroscience is very proud to announce Dr. Maria Ioannou, from the University of Alberta, has been awarded the CAN 2026 New Investigator Award View her profile: can-acn.org/awards/new-i...
Maria Ioannou wins the 2026 CAN New Investigator Award for groundbreaking research on lipid metabolism in the brain – Canadian Association for Neuroscience
Canadian Association for Neuroscience
can-acn.org
Neat!
Oliver Rocks@oliverrocks.bsky.social · 4mo agoCheck out our new release on BioRxiv co-lead by @pm-mueller.bsky.social 👉 rb.gy/lnrizk special🙏 to Severine Kunz #MDC @leventallab.bsky.social @andimicroscopy.bsky.social @ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM Are the days of discovering new cellular structures over?? /1
Spectral multiplexing is typically limited to 4-5 channels. Our new preprint introduces a framework that utilizes DNA barcoding and signal tuning to enable robust spectral unmixing and ground-truth benchmarking to achieve 15-plex subcellular profiling without cycling www.biorxiv.org/content/10.6...
Kristina@jekristina.bsky.social · 5mo agoEver felt constrained by the "4-color limit" in fluorescence imaging? We use DNA-barcoded labeling to build high-plex panels, enabling imaging of 15 targets across the full fluorescence spectrum. doi.org/10.64898/202... Grateful to @sinemsaka.bsky.social and all authors for making this possible.
Congrats to Jobert, Anna-Leigh, and Kai on showing how #BDNF amplifies #transcription, coordinates #RNA dynamics, and spatially regulates the #phosphoproteome. Beautiful cover art too! @jamessleigh.bsky.social @frattalab.bsky.social @uclqsion.bsky.social
Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons
BDNF promotes axon-regenerative gene expression, RNA metabolism, and kinase signaling in motor neurons.
science.org
Little nudge that early Bird discounts still on for this so if you're planning on coming, would recommend applying asap!
Jonny Nixon-Abell@abelljonny.bsky.social · 7mo ago‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏
Congrats folks! Another fabulous approach! 🤩
André Nadler@nadlerlab.bsky.social · 5mo agoIt’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...
Mechanoresilience of #lysosomes conferred by TMEM63A. New study from Angelina S. Kim, Jing Ze Wu, Ruiqi Cai, and Spencer A. Freeman @sickkidsto.bsky.social: rupress.org/jcb/article/... #Membrane #lipid #Organelles #Immunology #Metabolism
These Bridge-like lipid transfer proteins are so amazing. Backward lipid flow from autophagosomes to ER through Atg2!
Journal of Cell Biology@jcb.org · 5mo agoReversible one-way #lipid transfer at ER–autophagosome #membrane contact sites via Atg2. New study from Li Hao, Kuninori Suzuki and colleagues @utokyoofficial.bsky.social: rupress.org/jcb/article/... #Microbiology #Organelles
💡💡💡 I can testify, CIMR is an awesome place to start your lab. We are currently advertising Fellowship sponsorship for new group leaders...feel free to check out the link below and get in touch if you have any questions! Please RT!! www.nature.com/naturecareer...
Fellowship Sponsorship for New Group Leaders - Cambridge, Cambridgeshire job with University of Cambridge - Cambridge Institute for Medical Research | 12856122
Sponsorship of postdoctoral researchers interested in applying for career development fellowships to establish research independence.
nature.com
