Excited to share that our work on ‘How the gut gets patterned during regeneration’ is out now cell.com/cell/fulltext/S0092-8674(26)00696-3 Thanks a lot to @priscaliberali.bsky.social @silviabarbiero.bsky.social @davidbrueckner.bsky.social @ehannezo.bsky.social and all co-authors! 🧵

Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

cell.com

It is out 😍 check it out!! Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning. @cschwayer.bsky.social @silviabarbiero.bsky.social @davidbrueckner.bsky.social @ehannezo.bsky.social www.cell.com/cell/fulltex...

Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

cell.com

Beautiful piece on how field-specific journals with high ethical standards, such as Development, don’t try to « Game » the impact factor system - and practical steps to move away from this inherently flawed metric as a researcher (see Box 2)

James Briscoe@jamesbriscoe.bsky.social · 2mo ago

As Editor of @dev-journal.bsky.social I get asked "What are you doing about your impact factor?" In our new editorial we say: Ask not what Dev can do for the impact factor. Ask what you can do for Dev's IF The IF is about how we all cite, review & assess each other's work doi.org/10.1242/dev....

It’s official! @bertacava26.bsky.social has received a Marie Skłodowska-Curie European Postdoctoral Fellowship 🚀🚀🚀 She will study proteostasis during embryo dormancy @babrahaminst.bsky.social Very well deserved. proud of this achievement & excited for the discoveries ahead 🐭⌛️

explorers at the farthest reaches of our knowledge 🤩 neuronal ribosomes, and their mysterious rRNA expansion segments immense story from the dream team @andschwarz.bsky.social & @muellermara.bsky.social in the @erin-schuman.bsky.social lab at @mpibrain.bsky.social ribosome structure♥️neurons

Mara Mueller@muellermara.bsky.social · 6mo ago

Mammalian cells form hibernating disomes akin to those in bacterial cells - but connected via ribosomal RNA www.science.org/doi/10.1126/... co-first with: @andschwarz.bsky.social with: @lea-dietrich.bsky.social, @sgiando.bsky.social, @erin-schuman.bsky.social and many more 🧵 0/6 #MolBio 🧪

Just out @natrevimmunol.nature.com RNA-binding proteins and ribonucleoproteins as determinants of immunity www.nature.com/articles/s41... gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.

RNA-binding proteins and ribonucleoproteins as determinants of immunity - Nature Reviews Immunology

RNA-binding proteins (RBPs) considerably expand the information content of the genome and can determine the lifespan, localization and function of RNA, thereby controlling when, where and how much pro...

nature.com

Post-doc job alert! We have an exciting opportunity for a post doc to join our team at the Babraham Institute, exploring ageing metabolism and epigenetics. babrahaminstitute.livevacancies.co.uk#/job/details...

RNA-binding proteins function through network effects, coordinately binding and weakly regulating many transcripts – or don’t they? Read our new preprint on how LIN28 controls developmental timing through only two targets, one mRNA, one miRNA. doi.org/10.64898/202...

heads up neuro bsky 😎 must-read seminal discoveries: ultimate translation of genetic information in the farthest reaches of the neuron ➡️ @erin-schuman.bsky.social & in cortex development ➡️ @debbysilver.bsky.social thanks again 🤝 @natrevneuro.nature.com Darran Yates for editorial collaboration

Nature Reviews Neuroscience@natrevneuro.nature.com · 9mo ago

The on-site, on-demand, neuronal gene machine — a Journal Club article by Matthew L. Kraushar @matthewkraushar.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...

Lates from the Briscoe lab: Lineage tracing of neural progenitors in 🐤& 👤 - demonstrates sequential binary decisions & persistence of spatial identity despite temporal competence changes. Congrats to Giulia and co 🍾🥂

Giulia Boezio@giulia-boezio.bsky.social · 9mo ago

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions 🧵👇 www.biorxiv.org/content/10.1...

And the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n

Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers www.magd.cam.ac.uk/news/profess...

We've updated our first #preprint from the lab! A collaboration with @jamesbriscoe.bsky.social 🔥 now including in vivo 🐭&👤 embryo data www.biorxiv.org/content/10.1...

Beautiful work from Nan Xu and the @studerl.bsky.social lab in @natcellbio.nature.com combining directed differentiation of hPSCs and genome-wide CRISPR screens to identify the epigenetic factors Menin and SUZ12 as regulators of developmental pace across germ layers. www.nature.com/articles/s41...

Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timing - Nature Cell Biology

Xu et al. perform a whole-genome CRISPR-Cas9 knockout screen using directed differentiation systems. They find that MEN1 and SUZ12 modulate human developmental timing by epigenetically controlling biv...

nature.com

New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social

Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics

Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...

biorxiv.org

Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...

Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs

Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show rapid progression of transcriptional programs in specific tissues relative to morphological landmarks. This shift in...

cell.com

Excited for the @isscr.org‬ meeting in Hong Kong this week? #ISSCR2025 We've curated a 'Focus on stem cells' collection to complement the meeting, highlighting recent research and review-type articles discussing the wide range of studies using #stemcells. journals.biologists.com/dev/collecti...

Today we've announced the new Faraday Fellowship accelerated international route, which will grant up to £30 million in funding over the next two years to attract global talent and support the development of world-leading research groups in the UK: #RSGrants royalsociety.org/news/2025/05...

Royal Society announces £30m fund to attract global talent over next two years | Royal Society

International recruitment scheme comes amid announcement of Government principles for 10-year research funding

royalsociety.org

So proud of this work finally out in @natmicrobiol.nature.com! We examined antigenic variation in malaria parasites at single-cell level and found a surprising level of diversity. Make sure to check it out and don’t miss my talk on Thursday to hear about this story! #malaria #scRNA-Seq #EMBLMalaria

Kirk Deitsch@kirkdeitsch.bsky.social · last yr.

Very happy to congratulate @fra-florini.bsky.social and Joe Visone for the publication of their recent work on antigenic variation by malaria parasites: rdcu.be/emjbn and an earlier version here: www.biorxiv.org/content/10.1.... Francesca will present some of this work next week at BioMalPar 2025.

Hi @marklewandoski.bsky.social , You are already on the DevBio II starter pack. Please check to make sure you can see your @ handle. Devbio I was filled to its max of 150 members many months ago. So U stated a second pack which is almost full. go.bsky.app/2qUqVKE

@rrbehringer.bsky.social the first Dev Bio starter pack: go.bsky.app/M5AgJhn

The @embo.org #EvoDevoTempo ⏳ Paris 2025 just came to an end ⏳🧬 So grateful to be part of this inspiring community! Tons of ideas to take back with me - and already looking forward to the next edition! 🚀

As this @embo.org EvoDevoTempo Paris 2025 comes to close, my biggest takeaway message is that we absolutely must do this again! Cheers to the organizers and thanks for all the feedback on our work from the lovely Tempo community Until next ⏰ time ⏰

Matthew L. Kraushar@matthewkraushar.bsky.social · last yr.

having a lovely ⏱️time⏱️ at the #EMBO EvoDevoTempo meeting in paris very much a field defined by its multidisciplinarity and diversity of model systems, leading to discoveries that wouldn't be possible otherwise also, paris in the spring is definitely a thing

I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...

Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature

The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...

nature.com

Peer review completed within 7 days! Paying peer reviewers! Yes, it's possible. Fast & Fair peer review by @biologyopen.bsky.social More innovation from @biologists.bsky.social Details here: www.biorxiv.org/content/10.1...

Fast & Fair peer review: a pilot study demonstrating feasibility of rapid, high-quality peer review in a biology journal

Traditional peer review is slow, often delayed by the time-consuming process of identifying reviewers and lengthy review turnaround times. This study tests the feasibility of the Fast & Fair peer revi...

biorxiv.org

Biology Open@biologyopen.bsky.social · last yr.

We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL

Thrilled to start my collaboration in Lorenzo Calviello’s lab @translatomics.bsky.social at @humantechnopole.bsky.social! Excited to dive into Ribo-Seq, exchange ideas and uncover new insights on translational regulation. Looking forward to what’s ahead! Let’s get started! 🧬💻✨

Job opening in my research group!! Please share. I'm looking for a lab technician to join my small team investigating how chromatin structure regulates gene expression in C. elegans. www.fmi.ch/education-ca...

🚨New preprint alert!!! We show using #Celegans that mothers control the #ribosome levels of their offspring depending on their diet. Pioneered by fantastic Sigma Pradhan (not yet on 🟦). #worms biorxiv.org/content/10.1.... 🧵

Intergenerational control of ribosomes under dietary restriction

biorxiv.org

Last week, postdocs from @crg.eu & @babrahaminst.bsky.social came together to organise the International Postdoc Symposium, 2 incredible days full of science, dialogue & networking. These collaborations are so important! And Iris Uribesalgo, EU-LIFE Policy Officer, was there to talk about her role 😊